LEADER 05711nam 2200721Ia 450 001 9910831160903321 005 20230721005132.0 010 $a1-282-11320-8 010 $a9786612113208 010 $a0-470-43492-9 010 $a1-61583-174-6 010 $a0-470-43491-0 035 $a(CKB)1000000000719448 035 $a(EBL)427578 035 $a(OCoLC)437111240 035 $a(SSID)ssj0000207868 035 $a(PQKBManifestationID)11954585 035 $a(PQKBTitleCode)TC0000207868 035 $a(PQKBWorkID)10237098 035 $a(PQKB)10349844 035 $a(MiAaPQ)EBC427578 035 $a(EXLCZ)991000000000719448 100 $a20080726d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aNanochromatography and nanocapillary electrophoresis$b[electronic resource] $epharmaceutical and environmental analyses /$fImran Ali, Hassan Y. Aboul-Enein, Vinod K. Gupta 210 $aHoboken, N.J. $cJohn Wiley & Sons$dc2009 215 $a1 online resource (288 p.) 300 $aDescription based upon print version of record. 311 $a0-470-17851-5 320 $aIncludes bibliographical references and index. 327 $aNANOCHROMATOGRAPHY AND NANOCAPILLARY ELECTROPHORESIS; CONTENTS; PREFACE; ACKNOWLEDGMENTS; 1 Introduction; 1.1. Nanoanalyses; 1.2. Definition of Nanochromatography and Nanocapillary Electrophoresis; 1.3. Nanochromatography and Nanocapillary Electrophoresis; 1.4. Fabrication of Microdevices; 1.5. Developments in Nanoanalyses; 1.6. Data Integration; 1.7. Protocol of Nanoanalyses; 1.8. Scope of the Book; 1.9. Conclusion; References; 2 Fabrication of Microchips; 2.1. Introduction; 2.2. Substrates; 2.3. Techniques of Fabrication; 2.3.1. Glass Chips; 2.3.2. Quartz Chips; 2.3.3. Silica Chips 327 $a2.3.4. Polymer Chips2.3.5. Plastic Chips; 2.3.6. Chips and the Polymerase Chain Reaction; 2.4. Surface Modification; 2.4.1. Modification by Polymers; 2.4.2. Modification by Silica Gel; 2.4.3. Modification by Monolithics; 2.4.4. Modification by Sulfonation; 2.5. Designs of Chips; 2.6. Bindings in Chips; 2.7. Conclusion; References; 3 Instrumentation of Nanochromatography and Nanocapillary Electrophoresis; 3.1. Introduction; 3.2. Nanoliquid Chromatography (NLC); 3.2.1. Mobile Phase Reservoirs; 3.2.2. Mobile Phases and Flow Calibration; 3.2.3. Mobile Phase Tubings; 3.2.4. Solvent Delivery Pump 327 $a3.2.5. Sample Injector3.2.6. Separation Chips; 3.2.7. Detectors; 3.2.8. Recorder; 3.2.9. Sample Preparation Units; 3.3. Nanocapillary Electrophoresis; 3.3.1. Separation Chip; 3.3.2. Background Electrolyte and Its Reservoirs; 3.3.3. Sample Injection Port; 3.3.4. Detectors; 3.3.5. Recorder; 3.3.6. Sample Preparation Units; 3.4. Conclusion; References; 4 Detection in Nanochromatography and Nanocapillary Electrophoresis; 4.1. Introduction; 4.2. Mass Spectrometer Detectors; 4.3. Fluorescence Detectors; 4.4. Electrochemical Detectors; 4.5. Element Specific Detectors; 4.6. Miscellaneous Detectors 327 $a4.7. ConclusionReferences; 5 Sample Preparation in Nanochromatography and Nanocapillary Electrophoresis; 5.1. Introduction; 5.2. Sample Preparation; 5.3. Sampling; 5.3.1. Biological Samples; 5.3.1.1. Blood; 5.3.1.2. Urine; 5.3.1.3. Tissues; 5.3.1.4. Plants; 5.3.1.5. Food Stuffs; 5.3.2. Environmental Samples; 5.3.2.1. Air; 5.3.2.2. Water; 5.3.2.3. Sediment and Soils; 5.4. Preservation; 5.5. Filtration; 5.6. Digestion/Homogenization; 5.7. Extractions; 5.8. Clean Up; 5.9. Preconcentration; 5.10. Off-Line Nanosample Preparation Methods; 5.10.1. Nano Solid Phase Extractions 327 $a5.10.2. Nano Membrane Extractions5.10.3. Nano Miscellaneous Extractions; 5.11. Online Nanosample Preparation Methods; 5.12. Conclusion; References; 6 Nano-High Performance Liquid Chromatography; 6.1. Introduction; 6.2. Nano-HPLC; 6.3. Applications; 6.3.1. Nano-HPLC of Biological Matrices; 6.3.1.1. Proteomics; 6.3.1.2. Drugs Development and Design; 6.3.1.3. Environmental Analysis; 6.4. Optimization of Separations in Nano-HPLC; 6.5. Troubleshooting in Nano-HPLC; 6.6. Conclusion; References; 7 Nanocapillary Electrochromatography and Nanomicellar Electrokinetic Chromatography; 7.1. Introduction 327 $a7.2. Nanocapillary Electrochromatography 330 $aDetection of drugs at low concentration is required in a variety of biological and medical situations, in order to avoid harmful side effects posed by some drug residues. The book details the instrumentation, detection, and application of nano chromatography (that is, any chromatographic and capillary electrophoretic method dealing with the detection of a sample at nano gram per liter or lower) and capillary electrophoresis in the analyses of biological and environmental samples. Methods discussed include: Nano Gas Chromatography, Nano Capillary Electrophoresis, Nano Chiral Chromatography, Mic 606 $aChromatographic analysis 606 $aCapillary electrophoresis 606 $aDrugs$xAnalysis 606 $aPollutants$xAnalysis 606 $aNanoparticles$xAnalysis 615 0$aChromatographic analysis. 615 0$aCapillary electrophoresis. 615 0$aDrugs$xAnalysis. 615 0$aPollutants$xAnalysis. 615 0$aNanoparticles$xAnalysis. 676 $a543.8 676 $a543/.8 700 $aAli$b Imran$01345554 701 $aAboul-Enein$b Hassan Y$098954 701 $aGupta$b Vinod K.$f1953-$01638984 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910831160903321 996 $aNanochromatography and nanocapillary electrophoresis$93981702 997 $aUNINA