LEADER 03116nam 2200625Ia 450 001 9910451324003321 005 20200520144314.0 010 $a1-281-89708-6 010 $a9786611897086 010 $a981-270-136-2 035 $a(CKB)1000000000334358 035 $a(EBL)296094 035 $a(OCoLC)476063316 035 $a(SSID)ssj0000127561 035 $a(PQKBManifestationID)11141478 035 $a(PQKBTitleCode)TC0000127561 035 $a(PQKBWorkID)10054415 035 $a(PQKB)11680412 035 $a(MiAaPQ)EBC296094 035 $a(WSP)00000752 035 $a(Au-PeEL)EBL296094 035 $a(CaPaEBR)ebr10173947 035 $a(CaONFJC)MIL189708 035 $a(OCoLC)228170004 035 $a(EXLCZ)991000000000334358 100 $a20040903d2005 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aComputational biology of cancer$b[electronic resource] $electure notes and mathematical modeling /$fDominik Wodarz and Natalia Komarova 210 $aHackensack, NJ $cWorld Scientific$d2005 215 $a1 online resource (266 p.) 300 $aDescription based upon print version of record. 311 $a981-256-027-0 320 $aIncludes bibliographical references and index. 327 $aPreface; Contents; Chapter 1 Cancer and somatic evolution; Chapter 2 Mathematical modeling of tumorigenesis; Chapter 3 Cancer initiation: one-hit and two-hit stochastic models; Chapter 4 Microsatellite and chromosomal instability in sporadic and familial cancers; Chapter 5 Cellular origins of cancer; Chapter 6 Costs and benefits of chromosomal instability; Chapter 7 DNA damage and genetic instability; Chapter 8 Tissue aging and the development of cancer; Chapter 9 Basic models of tumor inhibition and promotion; Chapter 10 Mechanisms of tumor neovascularization 327 $aChapter 11 Cancer and immune responsesChapter 12 Therapeutic approaches: viruses as anti-tumor weapons; Appendix A Exact formula for total probability of double mutations; Bibliography; Index 330 $aThe book shows how mathematical and computational models can be used to study cancer biology. It introduces the concept of mathematical modeling and then applies it to a variety of topics in cancer biology. These include aspects of cancer initiation and progression, such as the somatic evolution of cells, genetic instability, and angiogenesis. The book also discusses the use of mathematical models for the analysis of therapeutic approaches such as chemotherapy, immunotherapy, and the use of oncolytic viruses. 606 $aCancer$xMathematical models 606 $aCancer$xResearch 608 $aElectronic books. 615 0$aCancer$xMathematical models. 615 0$aCancer$xResearch. 676 $a616.99/4/00724 700 $aWodarz$b Dominik$0721741 701 $aKomarova$b Natalia L$0721742 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910451324003321 996 $aComputational biology of cancer$92183696 997 $aUNINA LEADER 02942nam 2200613Ia 450 001 9910831076403321 005 20230421044601.0 010 $a1-282-68190-7 010 $a9786612681905 010 $a0-470-14144-1 010 $a0-470-14197-2 035 $a(CKB)1000000000376712 035 $a(EBL)455896 035 $a(OCoLC)609844619 035 $a(SSID)ssj0000356311 035 $a(PQKBManifestationID)11224445 035 $a(PQKBTitleCode)TC0000356311 035 $a(PQKBWorkID)10349110 035 $a(PQKB)10041809 035 $a(MiAaPQ)EBC455896 035 $a(EXLCZ)991000000000376712 100 $a19930915d1993 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aModern nonlinear optics$hPart 2$b[electronic resource] /$fedited by Myron Evans, Stanis?aw Kielich 210 $aNew York $cWiley$dc1993 215 $a1 online resource (850 p.) 225 1 $aAdvances in chemical physics ;$vv. 85/2 300 $aDescription based upon print version of record. 311 $a0-471-57546-1 320 $aIncludes bibliographical references and indexes. 327 $aMODERN NONLINEAR OPTICS Part 2; CONTENTS; HOLOGRAPHY AND DOUBLE PHASE CONJUGATION; LASER AND PULSED-LASER NMR SPECTROSCOPY; SOME PROPERTIES OF LONGITUDINAL FIELDS AND PHOTONS; FREQUENCY-DEPENDENT CONTINUUM ELECTROMAGNETIC PROPERTIES OF A GAS OF SCATTERING CENTERS; ASPECTS OF THE OPTICAL KERR EFFECT AND COTTON-MOUTON EFFECT OF SOLUTIONS; AB INITIO COMPUTATIONS OF POLARIZABILITIES AND HYPERPOLARIZABILITIES OF ATOMS AND MOLECULES; SELECTION RULES FOR COHERENT AND INCOHERENT NONLINEAR OPTICAL PROCESSES; MOLECULAR THEORY OF HARMONIC GENERATION; THE INTERACTION OF SQUEEZED LIGHT WITH ATOMS 327 $aTHE EFFECTIVE EIGENVALUE METHOD AND ITS APPLICATION TO STOCHASTIC PROBLEMS IN CONJUNCTION WITH THE NONLINEAR LANGEVIN EQUATIONAUTHOR INDEX; SUBJECT INDEX 330 $aThe Advances in Chemical Physics series provides the chemical physics and physical chemistry fields with a forum for critical, authoritative evaluations of advances in every area of the discipline. 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