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100   $a19890425d1988      uy             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aMetastasis$b[electronic resource]
210   $aChichester, UK ;$aNew York $cWiley$d1988
215   $a1 online resource (268 p.)
225 1 $aCiba Foundation symposium ;$v141
300   $a"Symposium on Metastasis, held at the Ciba Foundation, London, 19-21 April 1988. Editors: Gregory Bock (organizer) and Julie Whelan" --P.
300   $a"A Wiley-Interscience publication."
311   $a0-471-91513-0 
320   $aIncludes bibliographies and indexes.
327   $aMETASTASIS; Contents; Participants; Introduction; Tissue organizational stability and intercelIular invasion; Functional role of specific secreted and cell surface molecules in tumour cell invasion and metastasis; Adhesion mechanisms in embryogenesis and in cancer invasion and metastasis; The cell interaction sites of fibronectin in tumour metastasis; Oncogene induction of metastases; Adhesive properties of metastasizing tumour cells; Clonal changes in tumours during growth and progression evaluated by Southern gel analysis of random integrations of foreign DNA
327   $aMolecuIar genetics of metastasisThe reversal of the metastatic phenotype by gene transfer; Inhibitors of collagenase IV and cell adhesion reduce the invasive activity of malignant tumour cells; Macrophage therapy of cancer metastasis; Clinical aspects of metastases; Index of contributors; Subject index
330   $aAn international group of researchers addresses basic mechanism involved in the metastatic spread of tumors and considers new methods of prevention and treatment. Compares behavior of normal and abnormal cells, with emphasis on cell surface mechanisms--especially invasive processes--and inhibitors that might prevent metastasis. Also discusses determination of the metastatic genotype, the role of the immune system, and reduction of metastasis via liposome-activated macrophages.
410  0$aCiba Foundation symposium ;$v141.
606   $aMetastasis$vCongresses
606   $aInternal medicine
615  0$aMetastasis
615  0$aInternal medicine.
676   $a591.2
676   $a616.99
676   $a616.992071
701   $aBock$b Gregory$0322650
701   $aWhelan$b Julie$0322651
712 12$aSymposium on Metastasis$f(1988 :$eCiba Foundation)
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906   $aBOOK
912   $a9910831065503321
996   $aMetastasis$93928282
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