LEADER 03774nam 2200481 450 001 9910831062703321 005 20211005191722.0 010 $a1-5231-2826-7 010 $a1-119-31379-1 010 $a1-119-31377-5 010 $a1-119-31378-3 035 $a(MiAaPQ)EBC5825592 035 $a(EXLCZ)994330000000010177 100 $a20190806d2019 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHPLC and UHPLC for practicing scientists /$fMichael W. Dong 205 $aSecond edition. 210 1$aHoboken, New Jersey :$cWiley,$d[2019] 210 4$dİ2019 215 $a1 online resource (411 pages) 300 $aOriginally published: Modern HPLC for practicing scientists. 2006. 311 08$aPrint version: Dong, M. W., author. HPLC and UHPLC for practicing scientists Second edition. Hoboken, NJ : Wiley, 2019 9781119313762 (DLC) 2019002892 320 $aIncludes bibliographical references and index. 330 $a"Many things have changed in HPLC in the last ten years since the publication of the first edition.  First and foremost is the advent of UHPLC (ultra-high-pressure liquid chromatography) and the continuing migration of HPLC to UHPLC, the modern standard platform.  Since UHPLC is an improved and higher-performance HPLC platform based on the same chromatographic theories. they share many commonalities such as columns and instrument modules. The 2nd edition, therefore, includes a substantial overview of all the fundamentals and practice of HPLC to include updates on UHPLC.  There are three new chapters: UHPLC (standalone chapter on concepts, benefits, practice, and limitations), LC/MS, and the analysis of recombinant biologics particularly monoclonal antibodies (mAbs) used as therapeutics.  While all chapters are revised in the new edition, five chapters are mostly rewritten including HPLC columns, instrumentation, pharmaceutical analysis, method development, and regulatory aspects. To make the 2nd edition more attractive as a self-guided tutorial and a textbook, a section of problems and answers have been added to each chapter for comprehension assessments"--$cProvided by publisher. 330 $a"Many things have changed in HPLC in the last ten years since the publication of the first edition. First and foremost is the advent of UHPLC (ultra-high-pressure liquid chromatography) and the conttinuing migration of HPLC to UHPLC, the modern standard platform. Since UHPLC is an improved and higher-performance HPLC platform based on the same chromatographic theories. they share many commonalities such as columns and instrument modules. The 2nd edition, therefore, includes a substantial overview of all the fundamentals and practice of HPLC to include updates on UHPLC. There are three new chapters: UHPLC (standalone chapter on concepts, benefits, practice, and limitations), LC/MS, and the analysis of recombinant biologics particularly monoclonal antibodies (mAbs) used as therapeutics. While all chapters are revised in the new edition, five chapters are mostly rewritten including HPLC columns, instrumentation, pharmaceutical analysis, method development, and regulatory aspects"--$cProvided by publisher. 606 $aHigh performance liquid chromatography 606 $aDrugs$xAnalysis 615 0$aHigh performance liquid chromatography. 615 0$aDrugs$xAnalysis. 676 $a615.1901 686 $aSCI013010$2bisacsh 700 $aDong$b M. W.$0314333 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910831062703321 996 $aHPLC and UHPLC for practicing scientists$93928261 997 $aUNINA