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200 10$aDesign of studies for medical research$b[electronic resource] /$fDavid Machlin, Michael J. Campbell
210   $aHoboken, NJ $cWiley$dc2005
215   $a1 online resource (286 p.)
300   $aDescription based upon print version of record.
311   $a0-470-84495-7 
320   $aIncludes bibliographical references (p. [246]-254) and index.
327   $aDesign of Studies for Medical Research; Contents; Preface; Chapter 1 What is Evidence?; Chapter 2 Measurement, Forms and Questionnaires; Chapter 3 Principles of Study Size Calculation; Chapter 4 Randomisation; Chapter 5 Cross-sectional and Longitudinal Studies; Chapter 6 Surveys, Cohort and Case-Control Studies; Chapter 7 Clinical Trials - General Issues; Chapter 8 Early Clinical Trials; Chapter 9 Phase III Trials; Chapter 10 Diagnosis; Chapter 11 Prognostic Factor Studies; References; Tables; Index
330   $aThe same careful rigour imposed on the design of phase III randomised controlled trials is not always applied to medical research in other areas such as trials conducted at earlier stages of drug development.  With the emphasis that is now placed on evidence-based medicine, such care and rigour will inevitably impact on these areas with increasing attention turned to the quality of design.  This title describes what principles can be used to structure research effectively allowing for the required degree of accuracy. Written by two best selling authors, this book includes many examples f
606   $aMedicine$xResearch$xMethodology
615  0$aMedicine$xResearch$xMethodology.
676   $a610.72
676   $a610/.72
700   $aMachin$b David$f1939-$0520765
701   $aCampbell$b Michael J$0125733
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