LEADER 04197nam 22005534a 450 001 9910830885503321 005 20170817203209.0 010 $a1-280-85429-4 010 $a9786610854295 010 $a3-527-60785-4 010 $a3-527-60722-6 035 $a(CKB)1000000000377307 035 $a(EBL)482234 035 $a(OCoLC)70113367 035 $a(SSID)ssj0000107847 035 $a(PQKBManifestationID)11142949 035 $a(PQKBTitleCode)TC0000107847 035 $a(PQKBWorkID)10016212 035 $a(PQKB)11345406 035 $a(MiAaPQ)EBC482234 035 $a(PPN)137621299 035 $a(EXLCZ)991000000000377307 100 $a20060807d2006 fy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aAutoantibodies and autoimmunity$b[electronic resource] $emolecular mechanisms in health and disease /$fedited by K. Michael Pollard 210 $aWeinheim $cWiley-VCH$dc2006 215 $a1 online resource (636 p.) 300 $aDescription based upon print version of record. 311 $a3-527-31141-6 320 $aIncludes bibliographical references and index. 327 $aPrefactory chapter : the importance of the autoantibody-defined epitope / Eng M. Tan -- Self/non-self recognition / Alan G. Baxter -- Central and peripheral tolerance / Robert L. Rubin -- T-B cell interactions in autoimmunity / Barbara Schraml and Stanford L. Peng -- Cell death and autoimmunity / Carlos A. Casiano and Fabio J. Pacheco -- Self-antigen modification and autoimmunity / Stuart M. Levine, Livia Casciola-Rosen, and Antony Rosen -- Detection of antibodies / Rufus W. Burlingame and Carol Peebles -- Synthetic peptides for the analysis of B-cell epitopes in autoantigens / Jean-Paul Briand and Sylviane Muller --Autoantibodies and systematic autoimmune diseases / Karsten Conrad and Michael Bachmann -- Autoantibodies in systematic lupus erythematosus / Falk Hiepe -- Autoantibodies in rheumatoid arthritis / Tsuneyo Mimori -- Autoantibodies and organ-specific autoimmunity / H. Bantel, J. Kneser, and M.P. Manns -- Autoantibodies in autoimmune thyroid disease / Osvaldo Martinez and Bellur S. Prabhakar -- Autoantibodies in diabetes / Sarah M. Weenink and Michael R. Christie -- Autoantibody recognition of cellular and subcellular organelles / Ivan Ras?ka and S?a?rka Ru?z?ic?kova? -- Antibody recognition of macromolecular structures / Erica A. Champion and Susan J. Baserga -- Autoantibodies and the cloning and characterization of cellular constituents / Edward K.L. Chan -- Tolerance and immunity to the Ro/La RNP complex / Catherine L. Keech, Tom P. Gordon, and James McCluskey -- Autoantibody recognition of functional sites / Carlo Selmi ... [et al.] -- Novel mechanisims of autoantibody induction and pathogenesis in experimental autoimmunity / Yulius Y. Setiady and Kenneth S.K. Tung -- Environmental factors that contribute to autoimmunity / Per Hultman -- Genetics of autoantibody production in mouse models of lupus / Dwight H. Kono and Argyrios N. Theofilopoulos -- Genetic manipulation / Matthew C. Pickering and Mariana Botto -- Perspectives / K. Michael Pollard. 330 $aThis is the first book to address all aspects of the biology of autoantibodies in a single volume, including a discussion of immunology, experimental models, clinical aspects, and the use of autoantibodies as probes in molecular and cellular biology. The editor, currently professor at the W.M. Keck Autoimmune Disease Center of The Scripps Research Institute, has assembled an all-star team of authors to report on the latest research, technologies, and applications. Following an introductory chapter, the book goes on to cover such topics as cellular mechanisms of autoantibody production, cli 606 $aAutoantibodies 606 $aAutoimmunity 615 0$aAutoantibodies. 615 0$aAutoimmunity. 676 $a616.079 701 $aPollard$b K. Michael$g(Kenneth Michael)$01670048 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830885503321 996 $aAutoantibodies and autoimmunity$94031632 997 $aUNINA