LEADER 01017nam2-2200361---450- 001 990003199860203316 005 20090224154129.0 010 $a3-215-01620-6 035 $a000319986 035 $aUSA01000319986 035 $a(ALEPH)000319986USA01 035 $a000319986 100 $a20090224d1976----km-y0itay50------ba 101 $ager 102 $aAT 105 $a||||||||001yy 200 1 $a<> : Lyrik$e2. Teilband$fherausgegeben von Eugen Thurnher 210 $aWien$cÖsterreichischer Bundesverlag fur Unterricht$dcopyr. 1976 215 $a81, 684 p.$cill.$d24 cm 410 0$12001 454 1$12001 461 1$1001000319982$12001 702 1$aTHURNHER,$bEugen 801 0$aIT$bsalbc$gISBD 912 $a990003199860203316 951 $aII.3.D.47/3.2$b1904 DSLL 959 $aBK 969 $aDSLL 979 $aDSLL$b90$c20090224$lUSA01$h1528 979 $aDSLL$b90$c20090224$lUSA01$h1541 979 $aDSLL$b90$c20090224$lUSA01$h1541 996 $aLyrik$91015248 997 $aUNISA LEADER 00994nam a2200265 i 4500 001 991002586989707536 005 20020508202754.0 008 960716s1957 uk ||| | eng 020 $a0521261902 035 $ab11031876-39ule_inst 035 $aPARLA165493$9ExL 040 $aDip.to Scienze dell'Antichitą$bita 100 1 $aNicol, Donald MacGillivray$0161945 245 14$aThe despotate of Epiros /$cby Donald M. Nicol 260 $aOxford :$bBasil Blackwell,$cc1957 300 $aXIII, 251 p. ;$c24 cm 500 $aBibliografia: p. 259-280. Indici 650 4$aEpiro (Grecia e Albania)$xStoria - Despotato, 1204-1318 650 4$aImpero bizantino$xStoria - 1081-1453 907 $a.b11031876$b02-04-14$c28-06-02 912 $a991002586989707536 945 $aLE007 956 NIC 01.01$g1$i2015000085023$lle007$o-$pE0.00$q-$rl$s- $t0$u1$v0$w1$x0$y.i11153179$z28-06-02 996 $aDespotate of Epiros$9862359 997 $aUNISALENTO 998 $ale007$b01-01-96$cm$da $e-$feng$guk $h4$i1 LEADER 05119nam 2200649 450 001 9910830864603321 005 20230421044511.0 010 $a1-281-84268-0 010 $a9786611842680 010 $a3-527-61503-2 010 $a3-527-61502-4 035 $a(CKB)1000000000376033 035 $a(EBL)482162 035 $a(OCoLC)289312334 035 $a(SSID)ssj0000229621 035 $a(PQKBManifestationID)12085625 035 $a(PQKBTitleCode)TC0000229621 035 $a(PQKBWorkID)10171954 035 $a(PQKB)10100975 035 $a(MiAaPQ)EBC482162 035 $a(EXLCZ)991000000000376033 100 $a20160819h19961996 uy 0 101 0 $ager 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aProtein phosphorylation /$fedited by F. Marks 210 1$aWeinheim, [Germany] :$cVCH,$d1996. 210 4$d©1996 215 $a1 online resource (409 p.) 300 $aDescription based upon print version of record. 311 $a3-527-29241-1 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aProtein Phosphorylation; Preface; Contents; List of contributors; List of Abbreviations; 1 The brain of the cell; 1.1 Signals and symbols; 1.2 Proteins as communicative molecules; 1.3 The discovery of protein phosphorylation; 1.4 Protein phosphorylation in prokaryotes; 1.5 Protein phosphorylation in eukaryotes; 1.5.1 Eukaryotic protein kinases: common features and diversities; 1.5.2 Control of protein kinase activity; 1.5.3 The problem of substrate specificity; 1.5.4 Regulatory signals for protein kinases and examples of signaling cross-talk 327 $a1.5.5 Protein tyrosine phosphorylation and the integrity of multicellular organisms1.6 Signal extinction by protein dephosphorylation; 1.7 Cancer: a cellular 'psychosis'; 1.8 Advancing beyond the metaphor: proteins as non-trivial machines; References; 2 cAMP-dependent protein kinase: structure, function and control; 2.1 Introduction; 2.2 Biochemistry of cAPK; 2.2.1 Principles of purification of cAPK; 2.2.2 The catalytic subunit (C-subunit); 2.2.3 Control of cAPK; 2.3 Cellular aspects of cAPK function and control; 2.3.1 In vivo control of cAPK; 2.3.2 Cellular location of cAPK subunits 327 $a2.4 Structural aspects of cAPK function2.4.1 Dynamics of substrate-induced fit in solution; 2.4.2 Crystal structure of cAPK C-subunit; 2.4.3 Aspects of future research on cAPK; 2.5 A quick look at the cGMP-dependent protein kinase: a close relative of cAPK; 2.6 Structural consequences of protein phosphorylation in general; 2.6.1 Immediate physical consequences; 2.6.2 Conformational change - indirect evidence; 2.6.3 Conformational change - direct evidence; 2.6.4 Structural effects in peptides; References; 3 Protein kinase C; 3.1 Introduction; 3.2 The protein kinase C isoenzyme family 327 $a3.2.1 The PKC subfamilies3.2.2 PKC isoenzyme structures: common features and differences3; 3.2.3 Regulation of PKC activity4; 3.3 Cellular functions of protein kinase C; 3.3.1 Activators and inhibitors as tools in PKC research; 3.3.2 Phorbol ester effects; 3.3.3 Are effects of phorbol esters and DAG reliable indicators of PKC action?; 3.3.4 Effects of altered PKC expression on cellular functions; 3.3.5 PKC substrates11; 3.3.6 How PKC may acquire substrate specificity; 3.4 Protein kinase C in disease; 3.4.1 Involvement of PKC expression in benign and malignant hyperproliferative diseases 327 $a3.4.2 Oncogenic and anti-oncogenic effects of protein kinase C expression3.4.3 Protein kinase C and skin tumor promotion; References; 4 Casein kinases; 4.1 The different classes of casein kinases; 4.2 Protein kinase CK2; 4.2.1 History; 4.2.2 Biochemical features; 4.2.3 Molecular structures. interaction of subunits and regulation mechanisms; 4.2.4 CK2 genes and their chromosomal locations; 4.2.5 Transcribed CK2 messages and transcription control; 4.2.6 Cell physiological roles of CK2; 4.2.7 CK2 in mitogenic signal transmission; 4.2.8 CK2 and the cell cycle; 4.3 Protein kinase CK1 327 $a4.3.1 Biochemical features and molecular structures of CK1 330 $aProtein phosphorylation is a key mechanism in cellular signaling. This volume presents a state-of-the-art survey of one of the most rapidly developing fields of biochemical research. Written by leading experts, it presents the latest results for some of the most important cellular pathways. Color plates illustrate structural or functional relationships, numerous references provide links to the original literature. 606 $aPhosphoproteins$xSynthesis 606 $aPhosphoproteins$xMetabolism 606 $aProtein kinases 615 0$aPhosphoproteins$xSynthesis. 615 0$aPhosphoproteins$xMetabolism. 615 0$aProtein kinases. 676 $a572.65 676 $a574.19245 702 $aMarks$b Friedrich$f1936- 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830864603321 996 $aProtein phosphorylation$983639 997 $aUNINA