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010   $a9786611381455
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100   $a20071026d2008      uy             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aBioorganic and medicinal chemistry of fluorine$b[electronic resource] /$fJean-Pierre Be?gue?, Danie?le Bonnet-Delpon ; translated from French by Julien Legros
210   $aHoboken, N.J. $cJohn Wiley & Sons$dc2008
215   $a1 online resource (385 p.)
300   $aTranslated from the French.
311   $a0-470-27830-7 
320   $aIncludes bibliographic references and index.
327   $aGeneral remarks on structural, physical, and chemical properties of fluorinated compounds -- Overview on the preparation of fluorinated compounds -- Effects of fluorine substitution on biological properties -- Fluorinated analogues of natural products -- Fluorinated derivatives of ?-amino acids and proteins -- Saccharidic fluorinated derivatives -- Inhibition of enzymes by fluorinated compounds -- Fluorinated drugs.
330   $a Provides a thorough overview of the role of fluorine in pharmaceutical science and development Includes chapters on fluorinated analogues of natural products, fluorinated amino acids and peptides, and derivatives of sugars Classifies marketed and in-development fluorinated pharmaceuticals according to their therapeutic classes
606   $aFluorine compounds$xTherapeutic use
606   $aFluorine$xPhysiological effect
606   $aOrganofluorine compounds
606   $aBioorganic chemistry
615  0$aFluorine compounds$xTherapeutic use.
615  0$aFluorine$xPhysiological effect.
615  0$aOrganofluorine compounds.
615  0$aBioorganic chemistry.
676   $a547.02
676   $a547/.02
700   $aBe?gue?$b Jean-Pierre$01627905
701   $aBonnet-Delpon$b Danie?le$01627906
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910830834403321
996   $aBioorganic and medicinal chemistry of fluorine$93964727
997   $aUNINA