LEADER 03361nam 2200637 a 450 001 9910784993303321 005 20200520144314.0 010 $a1-281-27620-0 010 $a9786611276201 010 $a3-540-78248-6 024 7 $a10.1007/978-3-540-78248-3 035 $a(CKB)1000000000406917 035 $a(EBL)373069 035 $a(OCoLC)261325810 035 $a(SSID)ssj0000266519 035 $a(PQKBManifestationID)11191593 035 $a(PQKBTitleCode)TC0000266519 035 $a(PQKBWorkID)10302100 035 $a(PQKB)10049316 035 $a(DE-He213)978-3-540-78248-3 035 $a(MiAaPQ)EBC373069 035 $a(Au-PeEL)EBL373069 035 $a(CaPaEBR)ebr10223458 035 $a(CaONFJC)MIL127620 035 $a(PPN)123745896 035 $a(EXLCZ)991000000000406917 100 $a20081029d2008 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aValuation in life sciences$b[electronic resource] $ea practical guide /$fBoris Bogdan, Ralph Villiger 205 $a2nd ed. 210 $aHeidelberg $cSpringer$d2008 215 $a1 online resource (344 p.) 300 $aDescription based upon print version of record. 311 $a3-540-78247-8 320 $aIncludes bibliographical references and index. 327 $aFundamentals in Life Sciences -- Basics of Valuation -- Valuation in Life Sciences -- Exercises -- Case Studies. 330 $aValuation is a hot topic among life sciences professionals. There is no clear understanding on how to use the different valuation approaches and how to determine input parameters. Some do not value at all, arguing that it is not possible to get realistic and objective numbers out of it. Some claim it to be an art. In the following chapters we will provide the user with a concise val- tion manual, providing transparency and practical insight for all dealing with valuation in life sciences: project and portfolio managers, licensing executives, business developers, technology transfer managers, entrep- neurs, investors, and analysts. The purpose of the book is to explain how to apply discounted cash flow and real options valuation to life sciences p- jects, i.e. to license contracts, patents, and firms. We explain the fun- mentals and the pitfalls with case studies so that the reader is capable of performing the valuations on his own and repeat the theory in the exercises and case studies. The book is structured in five parts: In the first part, the introduction, we discuss the role of the players in the life sciences industry and their p- ticular interests. We describe why valuation is important to them, where they need it, and the current problems to it. The second part deals with the input parameters required for valuation in life sciences, i.e. success rates, costs, peak sales, and timelines. 606 $aValuation 606 $aBiotechnology industries$xFinance 615 0$aValuation. 615 0$aBiotechnology industries$xFinance. 676 $a332.63221 676 $a338.436151 700 $aBogdan$b Boris$01542286 701 $aVilliger$b Ralph$01542287 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910784993303321 996 $aValuation in life sciences$93794879 997 $aUNINA LEADER 03993nam 22005894a 450 001 9910830808903321 005 20230721005001.0 010 $a1-282-00929-X 010 $a9786612009297 010 $a1-4443-0057-1 010 $a1-4443-0058-X 035 $a(CKB)1000000000716027 035 $a(EBL)416533 035 $a(OCoLC)476248747 035 $a(SSID)ssj0000151239 035 $a(PQKBManifestationID)11158124 035 $a(PQKBTitleCode)TC0000151239 035 $a(PQKBWorkID)10281428 035 $a(PQKB)10867173 035 $a(MiAaPQ)EBC416533 035 $a(EXLCZ)991000000000716027 100 $a20080404d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 04$aThe evidence base of clinical diagnosis$b[electronic resource] $etheory and methods of diagnostic research /$fedited by J. Andre? Knottnerus, Frank Buntinx 205 $a2nd ed. 210 $aOxford ;$aHoboken, NJ $cWiley-Blackwell Pub./BMJ Books$d2009 215 $a1 online resource (318 p.) 300 $aIncludes index. 311 $a1-4051-5787-9 320 $aIncludes bibliographical references. 327 $aGeneral introduction : evaluation of diagnostic procedures / J. Andre? Knottnerus, Frank Buntinx, and Chris van Weel -- The architecture of diagnostic research / R. Brian Haynes and John You -- Assessment of the accuracy of diagnostic tests : the cross-sectional study / J. Andre? Knottnerus and Jean W. Muris -- Diagnostic testing and prognosis : the randomised controlled trial in test evaluation research / Jeroen G. Lijmer and Patrick M.M. Bossuyt -- The diagnostic before : after study to assess clinical impact / J. Andre? Knottnerus, Geert-Jan Dinant, Onno P. Van Schayck -- Designing studies to ensure that estimates of test accuracy will travel / Les M. Irwig ... [et al.] -- Analysis of data on the accuracy of diagnostic tests -- J. Dik ... [et al.] -- Multivariable analysis in diagnostic accuracy studies : what are the possibilities? / F. Buntinx ... [et al.] -- 327 $aStandards of reporting on diagnostic accuracy studies / P. Bossuyt and Nynke Smidt -- Guidelines for conducting systematic reviews of studies evaluating the accuracy of diagnostic tests / Frank Buntinx, Bert Aertgeerts, and Petra Macaskill -- Producing and using clinical prediction rules / Tom Fahey and Johan Van der Lei -- Clinical problem solving and diagnostic decision making : a selective review of the cognitive research literature / Alan Schwartz and Arthur S. Elstein -- Improving test ordering and its diagnostic cost effectiveness in clinical practice : bridging the gap between clinical research and routine health care / Ron A.G. Winkens ... [et al.] -- Epilogue : overview of evaluation strategy and challenges / J. Andre? Knottnerus, Ann van den Bruel, and Frank Buntinx. 330 $aThis unique book presents a framework for the strategy and methodology of diagnostic research, in relation to its relevance for practice. Now in its second edition The Evidence Base of Clinical Diagnosis has been fully revised and extended with new chapters covering the STARD guidelines (STAndards for the Reporting of Diagnostic accuracy studies) and the multivariable analysis of diagnostic data. With contributions from leading international experts in evidence-based medicine, this book is an indispensable guide on how to conduct and interpret studies in clinical diagnosis 606 $aDiagnosis$xResearch$xMethodology 606 $aEvidence-based medicine 615 0$aDiagnosis$xResearch$xMethodology. 615 0$aEvidence-based medicine. 676 $a616.07/5 676 $a616.075 701 $aKnottnerus$b J. Andre?$01611933 701 $aBuntinx$b Frank$01611934 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830808903321 996 $aThe evidence base of clinical diagnosis$93940425 997 $aUNINA