LEADER 02946nam 2200565Ia 450 001 9910830786003321 005 20170816121252.0 010 $a1-282-27906-8 010 $a9786612279065 010 $a0-470-49501-4 010 $a0-470-49500-6 035 $a(CKB)1000000000789931 035 $a(EBL)456205 035 $a(OCoLC)609844905 035 $a(SSID)ssj0000354691 035 $a(PQKBManifestationID)11259192 035 $a(PQKBTitleCode)TC0000354691 035 $a(PQKBWorkID)10314046 035 $a(PQKB)10021992 035 $a(MiAaPQ)EBC456205 035 $a(PPN)14480154X 035 $a(EXLCZ)991000000000789931 100 $a20090223d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aProtein targeting with small molecules$b[electronic resource] $echemical biology techniques and applications /$fedited by Hiroyuki Osada 210 $aHoboken, N.J. $cJohn Wiley & Sons$dc2009 215 $a1 online resource (310 p.) 300 $aDescription based upon print version of record. 311 $a0-470-12053-3 320 $aIncludes bibliographical references and index. 327 $aPROTEIN TARGETING WITH SMALL MOLECULES; CONTENTS; Contributors; Preface; 1 Chemical Biology Based on Small Molecule-Protein Interaction; 2 Target Profiling of Small Molecules; 3 Novel Applications of Affinity Beads; 4 Recent Developments and Advances in Chemical Arrays; 5 Use of the Phage Display Technique to Identify the Target Protein; 6 Development of Fluorescent Probes for Small Molecules; 7 Development of Small-Molecule Ligands and Inhibitors; 8 Interaction of a Biological Response Modifier with Proteins; 9 Chemical Biology of Cell Motility Inhibitors 327 $a10 Chemical Biology of Cell Surface Oligosaccharides11 Chemical Genomics Based on Yeast Genetics; 12 Data on Small Molecules and Their Target Proteins; Index 330 $aDiscover the link between the latest chemical biology approaches and novel drug therapies! Protein Targeting with Small Molecules: Chemical Biology Techniques and Applications takes readers beyond the use of chemical biology in basic research, providing a highly relevant look at techniques that can address the challenges of biology and drug design and development. This indispensable bench companion features up-to-date coverage of advances in chemistry and assesses their impact on developing new therapeutics, making it ideal for chemical biologists and medicinal chemists who a 606 $aProtein binding 606 $aMolecular probes 615 0$aProtein binding. 615 0$aMolecular probes. 676 $a572.633 701 $aOsada$b H$g(Hiroyuki),$f1954-$01691460 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830786003321 996 $aProtein targeting with small molecules$94067820 997 $aUNINA LEADER 01454nam0 22003011i 450 001 UON00400432 005 20231205104653.803 010 $a88-87115-44-3 100 $a20111116d2005 |0itac50 ba 101 $aita 102 $aIT 105 $a|||| ||||| 200 1 $aCampagne medievali$estrutture materiali, economia e società nell'insediamento rurale dell'Italia settentrionale (8.-10. secolo)$eAtti del Convegno$eNonantola (Mo), San Giovanni in Persiceto (Bo), 14-15 marzo 2003$fa cura di Sauro Gelichi 210 $aMantova$cSAP Società Archeologica$d2005 215 $a290 p.$cill.$d30 cm 410 1$1001UON00087232$12001 $aDocumenti di archeologia$fcollana diretta da Gian Pietro Brogiolo e Sauro Gelichi$v37 606 $aINSEDIAMENTI UMANI$xItalia settentrionale$xCampagna$xSec. 8.-10.$3UONC080944$2FI 606 $aItalia settentrionale$xEconomia rurale$xSec. 8.-10.$3UONC080945$2FI 620 $dMantova$3UONL002154 676 $a338.10937$cAGRICOLTURA - Italia antica$v21 702 1$aGELICHI$bSauro$3UONV031302 712 $aSocietà Archeologica Padana$3UONV278758$4650 801 $aIT$bSOL$c20250808$gRICA 899 $aSIBA - SISTEMA BIBLIOTECARIO DI ATENEO$2UONSI 912 $aUON00400432 950 $aSIBA - SISTEMA BIBLIOTECARIO DI ATENEO$dSI Q 6 017 037 $eSI MC 34335 5 996 $aCampagne medievali$9467279 997 $aUNIOR