LEADER 01023nam--2200337---450 001 990000456940203316 005 20210810155238.0 010 $a88-459-0698-1 035 $a0045694 035 $aUSA010045694 035 $a(ALEPH)000045694USA01 100 $a20010521d1989----km y1itay5003----ba 101 0 $aita 102 $aIT 200 1 $aSulla saggezza mondana, sull'amore e sulla rinuncia$fBharthari$ga cura di Alessandro Passi 210 $aMilano$cAdelphi$d1989 215 $a261 p.$d22 cm 225 2 $aBiblioteca Adelphi$v0211 410 1$12001$aBiblioteca Adelphi$v0211 676 $a891.21 700 1$aBHARTHARI$0545188 702 1$aPASSI,$bAlessandro 801 0$aIT$bsalbc$gISBD 912 $a990000456940203316 951 $aVIII.2.A. 47(Varie Coll. 87/211)$b130632 LM$cVarie Coll. 951 $aXV.18.B. 70 (FDC 800 BHA)$b6141 FIL$cXV.18.B.$d549563 959 $aBK 969 $aUMA 969 $aFDECI 996 $aSulla saggezza mondana, sull'amore e sulla rinuncia$9889529 997 $aUNISA LEADER 05646nam 2200493 450 001 9910830782603321 005 20231003223458.0 010 $a3-527-83977-1 010 $a3-527-83975-5 035 $a(MiAaPQ)EBC7187271 035 $a(Au-PeEL)EBL7187271 035 $a(CKB)26068917400041 035 $a(EXLCZ)9926068917400041 100 $a20230428d2023 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aBiomedical micro- and nanorobots in disease treatment $edesign, preparation, and applications /$fChun Mao and Mimi Wan 210 1$aWeinheim, Germany :$cWILEY-VCH GmbH,$d[2023] 210 4$dİ2023 215 $a1 online resource (253 pages) 311 08$aPrint version: Mao, Chun Biomedical Micro- and Nanorobots in Disease Treatment Newark : John Wiley & Sons, Incorporated,c2023 9783527351022 320 $aIncludes bibliographical references and index. 327 $aCover -- Title Page -- Copyright -- Contents -- Preface -- Chapter 1 Introduction -- 1.1 Origin of Biomedical Micro? and Nanorobots -- 1.2 A Long Journey -- 1.3 Moment of Glory -- 1.4 Three Laws -- 1.5 Main Contents of this Book -- References -- Chapter 2 Definition and Classification -- 2.1 Definition -- 2.2 Classification -- References -- Chapter 3 Design and Preparation -- 3.1 Substrate Selection -- 3.1.1 Metal Materials -- 3.1.2 Inorganic Materials -- 3.1.3 Organic Materials -- 3.1.4 Natural Materials -- 3.1.5 Hybrid Materials -- 3.2 Driving System -- 3.2.1 Driving System Based on Biological Components -- 3.2.2 Driving System Based on External Fields -- 3.2.3 Driving System Based on Chemical Reactions -- References -- Chapter 4 Characterization -- 4.1 Characterization of Motion -- 4.1.1 In Aqueous Environment -- 4.1.2 In Complex Environments In Vitro -- 4.2 In Vivo Tracking Technologies -- 4.2.1 Fluorescence Imaging Technology -- 4.2.2 MRI Technology -- 4.2.3 Radionuclide Imaging Technology -- 4.2.4 Ultrasonic Imaging Technology -- 4.2.5 Other Imaging Methods -- References -- Chapter 5 Biosafety -- 5.1 Biosafety of Micro? and Nanorobot Substrate -- 5.1.1 Material Composition -- 5.1.2 Micro? and Nanoscale Influence -- 5.1.3 Interaction with Physiological Environment In Vivo -- 5.1.4 Ultimate Destiny -- 5.1.5 Genotoxicity -- 5.1.6 Research Method of Biosafety -- 5.2 Biosafety of Driving System of Micro? and Nanorobots -- 5.2.1 Biological Micro? and Nanorobots -- 5.2.2 Physical Field?Driven Micro? and Nanorobots -- 5.2.3 Chemical Reaction?Driven Micro? and Nanorobots -- 5.3 Biosafety of Autonomous Motion Behavior of Micro? and Nanorobots -- 5.4 Biosafety Evaluation Methods for Micro? and Nanorobots -- References -- Chapter 6 Autonomous Motion Behavior -- 6.1 Autonomous Motion Mechanism. 327 $a6.1.1 Motion Mechanism of Biological Micro? and Nanorobots -- 6.1.1.1 Bacteria -- 6.1.1.2 Sperm -- 6.1.1.3 Immune Cells -- 6.1.2 Motion Mechanism of Physical Field?Driven Micro? and Nanorobots -- 6.1.2.1 Magnetic Field?Driving Mode -- 6.1.2.2 Photic Driving Mode -- 6.1.2.3 Ultrasonic Field?Driving Mode -- 6.1.3 Motion Mechanism of Chemical Reaction?Driven Micro? and Nanorobots -- 6.1.3.1 Self?Electrophoresis Mode -- 6.1.3.2 Self?Diffusiophoresis Mode -- 6.1.3.3 Bubble Mode -- 6.2 Trend Behavior Mechanism -- 6.2.1 Magnetotactic System -- 6.2.2 Phototactic System -- 6.2.3 Chemotaxis System -- 6.3 Motion Control -- 6.3.1 Speed Control Mode -- 6.3.2 Direction Control Mode -- 6.3.3 Control of Start and Stop -- References -- Chapter 7 Functions -- 7.1 Moving in Complex Physiological Environment -- 7.2 Loading Power Source, Drug, or Imaging Agent -- 7.3 Targeting Specific Cells or Physiological Tissues -- 7.4 Promoting Cell Uptake and Improving Tissue Permeability -- 7.5 Imaging Capability -- 7.6 Information Interaction and Intelligent Decision -- 7.7 Diagnosis and Treatment of Disease -- References -- Chapter 8 For Cardiovascular Disease Treatment -- 8.1 Thrombus -- 8.2 Atherosclerosis -- 8.3 Cerebral Apoplexy -- References -- Chapter 9 For Cancer Treatment -- 9.1 Cancer Diagnosis -- 9.2 Targeting and Delivery -- 9.3 Treatment of Different Cancer Species -- 9.4 Treatment Mechanism -- 9.4.1 Chemotherapy -- 9.4.2 Metabolic Therapy -- 9.4.3 Gas Therapy -- 9.4.4 Optical Therapy -- 9.4.5 Biotherapy -- 9.4.6 Immunotherapy -- 9.4.7 Multimodal Combined Therapy -- 9.5 Theranostics -- References -- Chapter 10 For Other Diseases' Treatment -- 10.1 Ophthalmic Diseases -- 10.2 Orthopedic Diseases -- 10.3 Gastrointestinal Diseases -- 10.4 Neurological Diseases -- 10.5 Bacterial Infection -- 10.6 Blood Heavy Metal Poisoning -- References. 327 $aChapter 11 Future Development Trend -- 11.1 Biosafety of Micro? and Nanorobots -- 11.2 New Materials and Technologies of Micro? and Nanorobots -- 11.3 Intelligent Micro? and Nanorobots -- 11.4 New Treatment Mode -- 11.5 New Detection Technology for Micro? and Nanorobots -- 11.6 Outlook and Future Challenges -- References -- Postscript -- Glossary -- Index -- EULA. 606 $aBiomedical engineering 606 $aDiseases$xTreatment 606 $aMicrorobots 615 0$aBiomedical engineering. 615 0$aDiseases$xTreatment. 615 0$aMicrorobots. 676 $a610.28 700 $aMao$b Chun$c(Writer on microrobots),$01691443 702 $aWan$b Mimi 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830782603321 996 $aBiomedical micro- and nanorobots in disease treatment$94067792 997 $aUNINA