LEADER 02469oam 2200613I 450 001 9910451554603321 005 20200520144314.0 010 $a1-134-88344-7 010 $a0-203-41988-X 010 $a1-280-33651-X 024 7 $a10.4324/9780203419885 035 $a(CKB)1000000000251449 035 $a(EBL)180143 035 $a(OCoLC)275230521 035 $a(SSID)ssj0000081330 035 $a(PQKBManifestationID)11331669 035 $a(PQKBTitleCode)TC0000081330 035 $a(PQKBWorkID)10113013 035 $a(PQKB)10510801 035 $a(MiAaPQ)EBC180143 035 $a(Au-PeEL)EBL180143 035 $a(CaPaEBR)ebr10057708 035 $a(CaONFJC)MIL33651 035 $a(OCoLC)51520354 035 $a(EXLCZ)991000000000251449 100 $a20180331d1995 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aLesbian studies $esetting an agenda /$fTamsin Wilton 210 1$aLondon ;$aNew York :$cRoutledge,$d1995. 215 $a1 online resource (247 p.) 300 $aDescription based upon print version of record. 311 $a0-415-08656-6 311 $a0-415-08655-8 320 $aIncludes bibliographical references (p. [205]-228) and index. 327 $aBook Cover; Title; Contents; Preface; Acknowledgements; Introduction: lesbian what?; Deviant pedagogies: the nature of lesbian studies; The nature of the beast: what is a lesbian?; Invisible and erased: uses and abuses of history; What is this thing called? Models of sexual identity; Orthodoxy within disobedience: lesbians and feminists; Stories and storytellers: lesbian literary studies; Lesbians studying culture: studying lesbian culture; The social lesbian; Subject to control: lesbians and the state; Bibliography; Index 330 $aAn academic approach to both gender and the erotic, which clarifies the damaging influence of heterosexism and examines Lesbian treatment in sociology, psychology, social policy, cultural studies, film theory and history. 606 $aGay and lesbian studies 606 $aFeminist theory 608 $aElectronic books. 615 0$aGay and lesbian studies. 615 0$aFeminist theory. 676 $a305.48/9664 700 $aWilton$b Tamsin.$0893459 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910451554603321 996 $aLesbian studies$91995868 997 $aUNINA LEADER 04082nam 2200601Ia 450 001 9910830686103321 005 20170814191054.0 010 $a1-282-68958-4 010 $a9786612689581 010 $a0-470-68626-X 010 $a0-470-68670-7 035 $a(CKB)2550000000012498 035 $a(EBL)516964 035 $a(OCoLC)612432913 035 $a(SSID)ssj0000426524 035 $a(PQKBManifestationID)11257655 035 $a(PQKBTitleCode)TC0000426524 035 $a(PQKBWorkID)10389264 035 $a(PQKB)10229591 035 $a(MiAaPQ)EBC516964 035 $a(PPN)149878869 035 $a(EXLCZ)992550000000012498 100 $a20091113d2010 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aQuantitative modeling in toxicology$b[electronic resource] /$feditors, Kannan Krishnan, Melvin E. Andersen 210 $aChichester, West Sussex ;$aHoboken $cJohn Wiley & Sons$d2010 215 $a1 online resource (505 p.) 300 $aDescription based upon print version of record. 311 $a0-470-99809-1 320 $aIncludes bibliographical references and index. 327 $aQuantitative Modeling in Toxicology; Contents; Preface; About the Editors; About the Book; List of Contributors; SECTION 1 INTRODUCTION; 1 Quantitative Modeling in Toxicology: An Introduction; SECTION 2 PHYSIOLOGICALLY-BASED TOXICOKINETIC AND PHARMACOKINETIC (PBPK) MODELING; 2 PBPK Modeling: A Primer; 3 Pharmacokinetic Modeling of Manganese - An Essential Element; 4 Physiologically Based Modeling of Pharmacokinetic Interactions in Chemical Mixtures; 5 Physiological Parameters and Databases for PBPK Modeling; SECTION 3 MODELING TOXICANT-TARGET INTERACTIONS; 6 Modeling Cholinesterase Inhibition 327 $a7 Modeling of Protein Induction and Dose-Dependent Hepatic Sequestration8 Bistable Signaling Motifs and Cell Fate Decisions; 9 Ultrasensitive Response Motifs in Biochemical Networks; 10 Gene and Protein Expression - Modeling Nested Motifs in Cellular and Tissue Response Networks; 11 Modeling Liver and Kidney Cytotoxicity; SECTION 4 MODELING TISSUE AND ORGANISM RESPONSES; 12 Computational Model for Iodide Economy and the HPT Axis in the Adult Rat; 13 Two-Stage Clonal Growth Modeling of Cancer; 14 Statistical and Physiological Modeling of the Toxicity of Chemicals in Mixtures 327 $a15 (Q)SAR Models of Adverse Responses: Acute Systemic ToxicitySECTION 5 MODEL APPLICATION AND EVALUATION; 16 Modeling Exposures to Chemicals From Multiple Sources and Routes; 17 Probabilistic Reverse Dosimetry Modeling for Interpreting Biomonitoring Data; 18 Quantitative Modeling in Noncancer Risk Assessment; 19 Application of Physiologically Based Pharmacokinetic Modeling in Health Risk Assessment; 20 Uncertainty, Variability, and Sensitivity Analyses in Simulation Models; 21 Evaluation of Quantitative Models in Toxicology: Progress and Challenges; Index 330 $aGovernments around the world are passing laws requiring industry to assess the toxicity of the chemicals and products they produce, but to do so while reducing, refining, or even replacing testing on animals. 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