LEADER 08863nam 2200601Ia 450 001 9910830635303321 005 20221108100651.0 010 $a1-119-99029-7 010 $a1-283-40517-2 010 $a9786613405173 010 $a1-119-98993-0 010 $a0-470-98020-6 035 $a(CKB)3400000000000319 035 $a(StDuBDS)AH21634127 035 $a(SSID)ssj0000477488 035 $a(PQKBManifestationID)11347040 035 $a(PQKBTitleCode)TC0000477488 035 $a(PQKBWorkID)10502833 035 $a(PQKB)11669148 035 $a(MiAaPQ)EBC675200 035 $a(PPN)190214449 035 $a(EXLCZ)993400000000000319 100 $a20101129d2011 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMacrocycles$b[electronic resource] $econstruction, chemistry and nanotechnology applications /$fFrank Davis, Séamus Higson 210 $aChichester, West Sussex, U.K. $cWiley$d2011 215 $a1 online resource (640 p.) 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a0-470-71463-8 311 $a0-470-71462-X 320 $aIncludes bibliographical references and index 327 $aPreface. 1. Introduction. 1.1. Simple ring compounds. 1.2. Three dimensional aliphatic carbon structures. 1.3. Annulenes. 1.4. Multi-ring aromatic structures. 1.5. Porpyrins and phthalocanines. 1.6. Conclusions. References. 2. Cyclophanes. 2.1. Introduction to cyclophanes. 2.2. Cyclophanes with one aromatic system and aliphatic chain. 2.3. Cyclophanes with more than 1 aromatic ring. 2.4. Napthalenophanes and other aromatic systems. 2.5. Cyclophanes containing heteroaromatic systems. 2.6. Ferrocenophanes. References. 3. Crown ethers, cryptands and other compounds. 3.1. Introduction. 3.2. Crown ethers. 3.3. Simple complexes with crown ethers. 3.4. Azacrowns, cyclens and cyclams. 3.5. Crowns containing other heteroatoms. 3.6. Lariat and bibracchial crown ethers. 3.7. Cryptands. 3.8. Spherands. 3.9. Combined and multiple systems. 3.10. Applications of crown ethers and related compounds. 3.11. Conclusions. References. 4. Calixarenes. 4.1. Introduction to calixarenes. 4.2. History of the calixarenes. 4.3. Structures of calixarenes. 4.4. Chemical modification of calixarenes. 4.5. Complexes with calixarenes. 4.6. Bis- and multicalixarenes. 4.7. Oxacalixarenes, azacalixarenes and thiacalixarenes. 4.8. Resorcinarenes - synthesis and structure. 4.9. Cavitands and carcerands. 4.10. Uses of calixarenes and conclusions. References. 5. Heterocalixarenes and calixnaphthalenes. 5.1. Introduction to heterocalixarenes and calixnaphthalenes. 5.2. Calixnaphthalenes. 5.3. Tropolone based macrocycles. 5.4. Calixfurans. 5.5. Calixpyrroles. 5.6. Calixindoles, calixpyridines and calixthiophenes. 5.7. Conclusions. References. 6. Cyclodextrins. 6.1. Introduction to cyclodextrins. 6.2. Complex formation by cyclodextrins. 6.3. Cyclodextrins of other sizes. 6.4. Modification reactions of cyclodextrins. 6.5. Selectivity of cyclodextrins. 6.6. Multiple cyclodextrin systems. 6.7. Polymeric cyclodextrins. 6.8. Cyclodextrins combined with other macrocyclic systems. 6.9. Therapeutic uses of cyclodextrins. 6.10. Other uses of cyclodextrins. 6.11. Conclusions. References. 7. Cyclotriveratylenes and cryptophanes. 7.1. Introduction to cyclotriveratrylenes and cryptophanes. 7.2. Synthesis of cyclotriveratrylenes. 7.3. Modification of cyclotriveratrylenes. 7.4. Synthesis of optically active cyclotriveratrylenes. 7.5. Modification of the bridging groups. 7.6. Modification of the aromatic rings with organometallic groups. 7.7. Selective binding applications of cyclotriveratrylenes. 7.8. Analogues of CTV. 7.9. Cryptophanes - synthesis and structure. 7.10. Cryptophanes - chemical modification. 7.11. Complexes with cryptophanes. 7.12. Cryptophane/Xenon complexes. 7.13. Other uses of cryptophanes. 7.14. Hemicryptophanes. 7.15. Conclusions. References. 8. Cucurbiturils. 8.1. Introduction to cucurbiturils. 8.2. Complexation behaviour of simple cucurbiturils. 8.3. Modification of cucurbiturils. 8.4. Uses of cucurbiturils. 8.5. Hemicucurbiturils. 8.6. Conclusions. References. 9. Rotaxanes and catenanes. 9.1. Introduction to rotaxanes and catenanes. 9.2. Rotaxanes. 9.3. Rotaxanes as molecular machines. 9.4. Thin films of rotaxanes. 9.5. Polyrotaxanes. 9.6. Catenanes. 9.7. Switchable catenanes. 9.8. Catenanes on surfaces. 9.9. Polycatenanes and catenated polymers. 9.10. Natural catenanes. 9.11. Conclusions. References. 10. Other supermolecular systems, molecular motors, machines and nanotechnological applications. 10.1. Introduction. 10.2. Other molecular systems. 10.3. Molecular devices, motors and machines. 10.4. Conclusions. References. 330 $aProviding an essential introduction on this important class of molecules which underpin nanotechnology, this book describes how they can be used as nanotechnology building blocks, and their applications. 330 $bMacrocyclic molecules contain rings made up of seven or more atoms. They are interesting because they provide building blocks for synthesizing precise two or three dimensional structures - an important goal in nanotechnology. For example, they can be used to develop nanosized reaction vessels, cages, switches and shuttles, and have potential as components in molecular computers. They also have applications as catalysts and sensors. Macrocycles: Construction, Chemistry and Nanotechnology Applications is an essential introduction this important class of molecules and describes how to synthesise them, their chemistry, how they can be used as nanotechnology building blocks, and their applications. A wide range of structures synthesised over the past few decades are covered, from the simpler cyclophanes and multi-ring aromatic structures to vases, bowls, cages and more complex multi-ring systems and 3D architectures such as "pumpkins", interlocking chains and knots. Topics covered include: principles of macrocycle synthesis simple ring compounds multi-ring aromatic structures porphyrins and phthalocanines cyclophanes crown ethers, cryptands and spherands calixarenes, resorcinarenes, cavitands, carcerands, and heterocalixarenes cyclodextrins cucurbiturils cyclotriveratylenes rotaxanes catenanes complex 3D architectures, including trefoils and knots Macrocycles: Construction, Chemistry and Nanotechnology Applications distills the essence of this important topic for undergraduate and postgraduate students, and for researchers in other fields interested in getting a general insight into this increasingly important class of molecules. Macrocyclic molecules contain rings made up of seven or more atoms. They provide building blocks for synthesizing precise two or three dimensional structures - an important goal in nanotechnology. For example, they can be used to develop nanosized reaction vessel, cages, switches and shuttles, and have potential as components in molecular computers as switches, nano-valves and logic gates. They also have applications as catalysts and sensors. Macrocycles: Construction, Chemistry and Nanotechnology Applications is an essential introduction to this important class of molecules and describes how to synthesize them, their chemistry, how they can be used as nanotechnology building blocks, and their applications. A wide range of structures synthesized over the past few decades are covered, from the simpler cyclophanes and multi-ring aromatic structures to vases, bowls, cages and more complex multi-ring systems and 3D architectures such as "pumpkins", interlocking chains and knots. Some of the molecular classes covered include simple ring compounds, three dimensional aliphatic carbon structures, annulenes, multi-ring aromatic structures, porphyrins and phthalocyanines, cyclophanes, crown ethers, cryptands, spherands, calixarenes, resorcinarenes, cavitands, carcerands, heterocalixarenes, calixnaphthalenes, cyclodextins, cyclotriveratylenes, cryptophanes, cucurbituris, rotaxanes and catenanes. Macrocycles: Construction, Chemistry and nanotechnology Applications distills the essence of this important topic for undergraduate and postgraduates students, and for researchers in other fields who are interested in getting a general insight into this increasingly important class of molecules. 606 $aMacrocyclic compounds 606 $aMacromolecules 615 0$aMacrocyclic compounds. 615 0$aMacromolecules. 676 $a547.59 686 $aTEC021000$2bisacsh 700 $aDavis$b Frank$f1966-$01612563 701 $aHigson$b Se?amus$01612564 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830635303321 996 $aMacrocycles$93941435 997 $aUNINA LEADER 05463nam 2200637Ia 450 001 9910969052903321 005 20240313235751.0 010 $a1-61705-167-5 035 $a(CKB)2670000000387535 035 $a(EBL)1218688 035 $a(OCoLC)851972264 035 $a(SSID)ssj0000915798 035 $a(PQKBManifestationID)12377231 035 $a(PQKBTitleCode)TC0000915798 035 $a(PQKBWorkID)10868704 035 $a(PQKB)11172593 035 $a(Au-PeEL)EBL1218688 035 $a(CaPaEBR)ebr10720897 035 $a(CaONFJC)MIL539956 035 $a(MiAaPQ)EBC1218688 035 $a(EXLCZ)992670000000387535 100 $a20130130d2013 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aGynecologic oncology handbook $ean evidence-based clinical guide /$fMichelle F. Benoit, Marian Yvette Williams-Brown, Creighton L. Edwards 205 $a1st ed. 210 $aNew York, NY $cDemos Medical Publising, LLC$dc2013 215 $a1 online resource $cillustrations 300 $aDescription based upon print version of record. 311 08$a1-62070-005-0 320 $aIncludes bibliographical references and index. 327 $aCover; Title; Copyright; Contents; Preface; Chapter 1: Gynecologic Oncology Referral Parameters; I. Endometrial Cancer; II. Pelvic Mass; III. Cervical Cancer; IV. Vaginal Cancer; V. Vulvar Cancer; VI. Gestational Trophoblastic Disease; Chapter 2: Disease Sites; A: Preinvasive Disease; I. Cervical Intraepithelial Neoplasia (CIN); II. Vulvar Intraepithelial Neoplasia; III. Vaginal Intraepithelial Neoplasia (VAIN); IV. Dysplasia and HIV; References; B: Cervical Cancer; I. Characteristics; II. Pretreatment Workup; III. Histology; IV. Staging; V. Overall survival by stage; VI. Treatment 327 $aVII. Surgical TreatmentVIII. Radiotherapy; IX. Adjuvant Posthysterectomy Treatment; X. Advanced Disease; XI. Recurrent Disease; XII. Survival; XIII. Prognostic Factors for Survival; XIV. Follow-Up; XV. Notable Trials in Cervical Cancer; References; C: Ovarian Cancer; I. General Characteristics; II. General Workup; III. General Treatment; IV. Histology; V. General Staging; Epithelial Ovarian Cancer; I. Characteristics; II. Workup; III. Histology; IV. Staging; V. Treatment; VI. Chemotherapy for Epithelial Ovarian Cancer; VII. Treatment by Stage; VIII. Second-look laparotomy; IX. Recurrence 327 $aX. Secondary cytoreductionXI. Cerebellar degeneration; XII. Survival; XIII. Survival Care; XIV. Epithelial Ovarian Cancer Trials; Ovarian Tumors of Low Malignant Potential (LMP); I. Characteristics; II. Histology; III. Workup; IV. Staging; V. Treatment; VI. Recurrence; VII. Survival; VIII. Survival Care; Fallopian Tube Cancer; I. Characteristics; II. Workup; III. Histology; IV. Staging; V. Treatment; VI. Survival; VII. Survival care; Primary Peritoneal Cancer; Germ Cell Tumors (GCT); I. Characteristics; II. Workup; III. Staging; IV. Treatment; V. Recurrence; VI. Follow-Up 327 $aVII. Histological Subtypes and Directed TherapiesVIII. Germ Cell Tumor Trials; IX. Chemotherapy Protocols for Ovarian GCT; Sex Cord Stromal Tumors; I. Characteristics; II. Workup; III. Staging; IV. Treatment; V. Histology; VI. 5 Y Survival; VII. Sex Cord Stromal Tumor Trials; References; D: Uterine Cancer; I. Characteristics; II. Prognostic factors; III. Pretreatment Workup; IV. Histology; V. Staging; VI. Grade is specified as a 3-tiered system; VII. Treatment; VIII. Recurrence; IX. Postoperative hormonal replacement therapy; X. Synchronous ovarian neoplasm; XI. Survival; XII. Follow-Up 327 $aXIII. TamoxifenNotable Studies in Uterine Cancer; I. High-Risk Early-Stage Disease Adjuvant Therapy Studies; Uterine Sarcomas; I. Characteristics; V. Prognostic factors; VI. Follow-Up; References; E: Vulvar Cancer; I. Characteristics; II. Workup; III. Histology; IV. Staging; V. Treatment; VI. Recurrence; VII. Survival; VIII. Follow-up; Notable Studies; References; F: Vaginal Cancer; I. Characteristics; II. Pretreatment Workup; III. Histology; IV. Staging; V. Treatment; VI. Recurrent Disease; VII. Survival; VIII. Follow-up; G: Gestational Trophoblastic Disease; I. Characteristics 327 $aII. Histology 330 $aGynecologic Oncology Rotation Quick Reference provides a comprehensive yet concise, practical guide for fellows, residents, and specialist trainees in the diagnosis and management of gynecologic cancers. The book addresses the fundamentals of gynecologic oncology, including staging, surgical technique, comorbidity diagnosis and management, adjuvant therapies including chemotherapy and radiation, and survival and palliative care. The focus is on specific management decision-making and the book provides the basic information needed to guide the clinician on the ward or in the clinic including cl 606 $aGenerative organs, Female$xCancer 606 $aEvidence-based medicine 615 0$aGenerative organs, Female$xCancer. 615 0$aEvidence-based medicine. 676 $a616.99/465 700 $aBenoit$b Michelle F$01035137 701 $aWilliams-Brown$b Marian Yvette$01833236 701 $aEdwards$b Creighton L$01833237 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910969052903321 996 $aGynecologic oncology handbook$94408196 997 $aUNINA