LEADER 02383nam 22005894a 450 001 9910830619303321 005 20230617035326.0 010 $a1-280-51991-6 010 $a9786610519910 010 $a3-527-60369-7 010 $a3-527-60462-6 035 $a(CKB)1000000000377109 035 $a(EBL)481801 035 $a(OCoLC)190838421 035 $a(SSID)ssj0000151560 035 $a(PQKBManifestationID)11146912 035 $a(PQKBTitleCode)TC0000151560 035 $a(PQKBWorkID)10321189 035 $a(PQKB)10975965 035 $a(MiAaPQ)EBC481801 035 $a(EXLCZ)991000000000377109 100 $a20060807d2004 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aEvolutionary methods in biotechnology$b[electronic resource] $eclever tricks for directed evolution /$fedited by Susanne Brakmann and Andreas Schwienhorst 210 $aWeinheim $cWiley-VCH$dc2004 215 $a1 online resource (230 p.) 300 $aDescription based upon print version of record. 311 $a3-527-30799-0 320 $aIncludes bibliographical references and index. 327 $aIncludes CD-ROM in pocket attached to inside back cover. 330 $aMiniturization and high throughput assay technology have brought the power of molecular evolution to the bioscience laboratory. Applied wisely, the evolutionary approach can quickly yield the desired result even where other methods have failed.From library generation by random or directed mutagenesis to screening and selection techniques -- the crucial steps for successful evolutionary biotechnology are described in detail in this practical guide that also includes valuable troubleshooting hints on frequently encountered problems.Modern methods for the surface display of peptides and p 606 $aBiotechnology 606 $aMolecular evolution 606 $aGenetic engineering 615 0$aBiotechnology. 615 0$aMolecular evolution. 615 0$aGenetic engineering. 676 $a572.838 676 $a660.6 701 $aBrakmann$b Susanne$01713810 701 $aSchwienhorst$b Andreas$01713811 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830619303321 996 $aEvolutionary methods in biotechnology$94107083 997 $aUNINA