LEADER 05574nam 2200697 450 001 9910830571203321 005 20221231053559.0 010 $a3-527-68172-8 010 $a3-527-68780-7 010 $a3-527-68174-4 035 $a(CKB)3710000000121872 035 $a(EBL)1701417 035 $a(SSID)ssj0001322276 035 $a(PQKBManifestationID)11862279 035 $a(PQKBTitleCode)TC0001322276 035 $a(PQKBWorkID)11424953 035 $a(PQKB)10428054 035 $a(MiAaPQ)EBC1701417 035 $a(MiAaPQ)EBC4044587 035 $a(MiAaPQ)EBC7041985 035 $a(Au-PeEL)EBL7041985 035 $a(PPN)220885028 035 $a(EXLCZ)993710000000121872 100 $a20221231d2014 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aSide reactions in organic synthesis II $earomatic substitutions /$fFlorencio Zaragoza Do?rwald 205 $aSecond edition. 210 1$aWeinheim, Germany :$cWiley-VCH Verlag GmbH & Co. KGaA,$d[2014] 210 4$dİ2014 215 $a1 online resource (311 p.) 300 $aDescription based upon print version of record. 311 $a3-527-33721-0 320 $aIncludes bibliographical references and index. 327 $aSide Reactions in Organic Synthesis II; Contents; Preface; Glossary and Abbreviations; Journal Abbreviation List; Chapter 1 Electrophilic Alkylation of Arenes; 1.1 General Aspects; 1.1.1 Catalysis by Transition-Metal Complexes; 1.1.2 Typical Side Reactions; 1.2 Problematic Arenes; 1.2.1 Electron-Deficient Arenes; 1.2.2 Phenols; 1.2.3 Anilines; 1.2.4 Azoles; 1.3 Problematic Electrophiles; 1.3.1 Methylations; 1.3.2 Olefins; 1.3.3 Allylic Electrophiles; 1.3.4 Epoxides; 1.3.5 ?-Haloketones and Related Electrophiles; 1.3.6 Nitroalkanes; 1.3.7 Ketones; 1.3.8 Alcohols; References 327 $aChapter 2 Electrophilic Olefination of Arenes2.1 General Aspects; 2.2 Olefinations with Leaving-Group-Substituted Olefins; 2.3 Olefinations with Unsubstituted Olefins; 2.4 Olefinations with Alkynes; References; Chapter 3 Electrophilic Arylation of Arenes; 3.1 General Aspects; 3.2 Arylations with Aryl Halides; 3.2.1 Via Cationic Intermediates; 3.2.2 Via Radicals; 3.2.3 Via Transition-Metal Chelates; 3.2.4 By Transition-Metal Catalysis; 3.3 Arylations with Diazonium Salts; 3.4 Arylations with Other Functionalized Arenes; 3.5 Arylations with Unsubstituted Arenes; References 327 $aChapter 4 Electrophilic Acylation of Arenes4.1 General Aspects; 4.2 Problematic Arenes; 4.2.1 Dealkylation/Isomerization of Arenes; 4.2.2 Styrenes; 4.2.3 Anilines, Phenols, and Thiophenols; 4.2.4 Electron-Deficient Arenes; 4.2.5 Azoles; 4.3 Problematic Electrophiles; 4.3.1 Problematic Acyl Halides; 4.3.2 Carboxylic Esters and Lactones; 4.3.3 Carbonic Acid Derivatives; 4.3.4 Formic Acid Derivatives; 4.3.5 Mixed Carboxylic Anhydrides and Other Polyelectrophiles; References; Chapter 5 Electrophilic Halogenation of Arenes; 5.1 General Aspects; 5.2 Typical Side Reactions; 5.3 Regioselectivity 327 $a5.4 Catalysis5.5 Fluorinations; 5.6 Electron-Deficient Arenes; 5.6.1 Pyridines; 5.6.2 Benzoic Acid Derivatives; 5.7 Electron-Rich Arenes; 5.7.1 Phenols and Arylethers; 5.7.2 Anilines; 5.7.3 Azoles; 5.8 Sensitive Functional Groups; 5.8.1 Alkenes; 5.8.2 Amines; 5.8.3 Ethers; 5.8.4 Thiols and Thioethers; 5.8.5 Aldehydes, Ketones, and Other C-H Acidic Compounds; 5.8.6 Amides; References; Chapter 6 Electrophilic Formation of Aromatic C-N Bonds; 6.1 Nitration of Arenes; 6.1.1 Mechanisms; 6.1.2 Regioselectivity; 6.1.3 Catalysis; 6.1.4 Electron-Deficient Arenes; 6.1.5 Electron-Rich Arenes 327 $a6.1.5.1 Anilines6.1.5.2 Indoles; 6.1.5.3 Phenols; 6.2 Electrophilic Aromatic Aminations; 6.2.1 Typical Side Reactions; 6.3 Electrophilic Aromatic Amidations; 6.3.1 Typical Side Reactions; References; Chapter 7 Electrophilic Formation of Aromatic C-S Bonds; 7.1 Sulfonylation; 7.1.1 General Aspects; 7.1.2 Typical Side Reactions; 7.2 Sulfinylation; 7.2.1 General Aspects; 7.2.2 Typical Side Reactions; 7.3 Sulfenylation; 7.3.1 General Aspects; 7.3.2 Typical Side Reactions; References; Chapter 8 Aromatic Nucleophilic Substitutions; 8.1 General Aspects; 8.1.1 Mechanisms; 8.1.2 Regioselectivity 327 $a8.1.3 Acid-/Base-Catalysis 330 $aFollowing in the footsteps of the successful ""Side Reactions in Organic Synthesis"" by the same, highly experienced author, this new textbook focuses on aromatic substitution reactions, both electrophilic and nucleophilic.The coverage is reader-friendly with each chapter dealing with a certain reaction class in terms of its scope and limitations in detail, and unique in its approach since unexpected and unwanted side reactions are hard to find in the literature.A valuable addition to the classical textbooks on organic chemistry, this is a must-have for graduate students as well as for 517 3 $aSide reactions in organic synthesis 2 517 3 $aSide reactions in organic synthesis two 606 $aAromatic compounds$xSynthesis 606 $aOrganic compounds$xSynthesis 606 $aAromatic compounds 615 0$aAromatic compounds$xSynthesis. 615 0$aOrganic compounds$xSynthesis. 615 0$aAromatic compounds. 676 $a547.6 700 $aDo?rwald$b Florencio Zaragoza$0875082 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830571203321 996 $aSide reactions in organic synthesis II$94085328 997 $aUNINA