LEADER 05258nam 2200625 a 450 001 9910830552803321 005 20190416220348.0 010 $a3-527-63513-0 010 $a1-283-30249-7 010 $a9786613302496 010 $a3-527-63514-9 010 $a3-527-63512-2 035 $a(CKB)3460000000003436 035 $a(EBL)700904 035 $a(SSID)ssj0000506255 035 $a(PQKBManifestationID)11337699 035 $a(PQKBTitleCode)TC0000506255 035 $a(PQKBWorkID)10512695 035 $a(PQKB)11377697 035 $a(MiAaPQ)EBC700904 035 $a(OCoLC)729726277 035 $a(EXLCZ)993460000000003436 100 $a20111119d2011 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aIndustrial scale natural products extraction$b[electronic resource] /$fedited by Hans-Jo?rg Bart and Stephan Pilz 210 $aWeinheim, Germany $cWiley-VCH$d2011 215 $a1 online resource (316 p.) 300 $aDescription based upon print version of record. 311 $a3-527-32504-2 320 $aIncludes bibliographical references and index. 327 $aIndustrial Scale Natural Products Extraction; Contents; Preface; List of Contributors; 1 Extraction of Natural Products from Plants - An Introduction; 1.1 Introduction; 1.2 Cultivation; 1.3 Extraction; 1.3.1 Solvents; 1.4 Extraction Techniques; 1.5 Purification; 1.5.1 Chromatography; 1.5.1.1 Adsorption Chromatography; 1.5.1.2 Partition Chromatography; 1.5.1.3 Ion Exchange Chromatography; 1.5.1.4 Gel Chromatography; 1.5.1.5 (Bio-) Affinity Chromatography; 1.5.2 Continuous Techniques; 1.5.2.1 True Moving Bed (TMB) Chromatography; 1.5.2.2 Simulated Moving Bed (SMB) Chromatography 327 $a1.5.2.3 Annular Chromatography1.5.2.4 Carrousel Adsorbers; References; 2 Solubility of Complex Natural and Pharmaceutical Substances; 2.1 Introduction; 2.2 Solubility Calculations; 2.2.1 Solubility of a Pure Solute in Solvents and Solvent Mixtures; 2.2.2 pH-Dependence of Solubility; 2.2.3 Solubility of Racemic Compounds; 2.3 Thermodynamic Modeling; 2.3.1 PC-SAFT Equation of State; 2.3.1.1 Hard-Chain Contribution Ahc; 2.3.1.2 Dispersion Contribution Adisp; 2.3.1.3 Association Contribution Assoc; 2.3.2 Estimation of PC-SAFT Parameters; 2.4 Examples 327 $a2.4.1 Solubility of Estriol, Estrone, and Sitosterol in Different Solvents2.4.2 Solubility of Beta-carotene in Supercritical Carbon Dioxide; 2.4.3 Solubility of Paracetamol in Pure Solvents and Solvent Mixtures; 2.4.4 Solubility of dl-Methionine as Function of pH; 2.4.5 Solubility of Mandelic Acid Enantiomers and Racemic Mandelic Acid in Water; 2.5 Summary; Symbols; Latin Symbols; Greek Symbols and Special Characters; Superscripts; Subscripts; Appendix; Hard-chain Reference Contribution; Dispersion Contribution; Association Contribution; References; 3 Alternative Solvents in Plant Extraction 327 $a3.1 Introduction3.2 Ionic Liquids in the Extraction of Natural Compounds from Plant and Fungi; 3.2.1 Characteristics of Ionic Liquids; 3.2.1.1 Physicochemical Properties; 3.2.1.2 Environmental and Safety Aspects; 3.2.2 Application of Ionic Liquids in Plant Extraction; 3.2.2.1 Application of ILs in Extraction; 3.2.2.2 Removal of Target Substance from Extract and Separation of Solvent from Spent Biomass; 3.2.2.3 Example 1: Extraction of Artemisinin; 3.2.2.4 Example 2: Extraction of Lignin; 3.3 Surfactants and Aqueous Two-Phase Systems in Plant Extraction 327 $a3.3.1 Characteristics of Surfactant-Water Mixtures3.3.2 Behavior of Nonionic Surfactants in Aqueous Solution; 3.3.3 Micellar Extraction and Cloud Point Extraction; 3.3.4 Reversed Micellar Extraction; 3.3.5 Equilibrium Partition of Target Substances in Aqueous Surfactant Solutions; 3.3.6 Examples for the Use of Surfactants in Plant Extraction; 3.3.6.1 Plant Extraction Using Micellar and Cloud Point Extraction; 3.3.6.2 Plant Extraction Using Reverse Micelles; 3.4 Summary; References; 4 High Pressure Processing; 4.1 Introduction; 4.2 Supercritical Fluids; 4.2.1 General; 4.2.2 Physical Properties 327 $a4.2.3 Solvent Power and Solubility 330 $aCovering the latest technologies in process engineering, this handbook and ready reference features high pressure processing, alternative solvents and processes, extraction technologies and biotransformations -- describing greener, more efficient and sustainable techniques. The result is an expert account of engineering details from lab-scale experiments to large-scale industrial design. The major focus is on the engineering aspects of extraction with organic and supercritical solvents, ionic liquids or surfactant solutions, and is supplemented by aspects of both up- and downstream process 606 $aExtraction (Chemistry) 606 $aNatural products 615 0$aExtraction (Chemistry) 615 0$aNatural products. 676 $a622.2 701 $aBart$b Hans-Jo?rg$f1954-$01646611 701 $aPilz$b Stephan$01646612 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830552803321 996 $aIndustrial scale natural products extraction$93993714 997 $aUNINA LEADER 01943oas 2200589 a 450 001 9910895595103321 005 20251106213014.0 035 $a(DE-599)ZDB2618919-7 035 $a(OCoLC)652656284 035 $a(CONSER) 2010240806 035 $a(CKB)1000000000489768 035 $a(EXLCZ)991000000000489768 100 $a20100705a20039999 uy 101 0 $apor 135 $aurn|||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aPesquisa e desenvolvimento, engenharia de produc?a?o $eP & D 210 $a[Itajuba?, MG, Brazil] $cPrograma de Po?s Graduac?a?o em Engenharia de Produc?a?o, Universidade Federal de Itajuba?$d2003- 311 08$a1679-5830 517 1 $aRevista Pesquisa e desenvolvimento, engenharia de produc?a?o 517 1 $aP & D 517 1 $aPesquisa e desenvolvimento 517 1 $aEngenharia de produc?a?o 606 $aProduction engineering$xResearch$vPeriodicals 606 $aProduction engineering$xResearch$zBrazil$vPeriodicals 606 $aProduction engineering$xResearch$2fast$3(OCoLC)fst01078296 607 $aBrazil$2fast$1https://id.oclc.org/worldcat/entity/E39QbtfRB9KGtqfkFTFbfB77QY 608 $aPeriodicals.$2fast 615 0$aProduction engineering$xResearch 615 0$aProduction engineering$xResearch 615 7$aProduction engineering$xResearch. 712 02$aUniversidade Federal de Itajuba?.$bPrograma de Po?s Graduac?a?o em Engenharia de Produc?a?o. 801 0$bSHS 801 1$bSHS 801 2$bOCLCQ 801 2$bIXA 801 2$bHEBIS 801 2$bCUS 801 2$bOCLCQ 801 2$bOCLCF 801 2$bOCLCQ 801 2$bOCLCA 801 2$bOCLCQ 801 2$bCUS 801 2$bOCLCL 801 2$bOCLCQ 906 $aJOURNAL 912 $a9910895595103321 996 $aPesquisa e desenvolvimento, engenharia de produção$94268465 997 $aUNINA