LEADER 03293nam 2200589Ia 450 001 9910830522003321 005 20230828214612.0 010 $a1-280-74301-8 010 $a9786610743018 010 $a0-470-79096-2 010 $a0-470-75529-6 010 $a1-4051-7143-X 035 $a(CKB)1000000000351280 035 $a(EBL)284227 035 $a(OCoLC)437176118 035 $a(SSID)ssj0000102782 035 $a(PQKBManifestationID)11117111 035 $a(PQKBTitleCode)TC0000102782 035 $a(PQKBWorkID)10061550 035 $a(PQKB)10669265 035 $a(MiAaPQ)EBC284227 035 $a(EXLCZ)991000000000351280 100 $a20060222d2006 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aAnaesthesia science$b[electronic resource] /$fedited by Nigel R. Webster and Helen F. Galley 210 $aMalden, Mass. $cBlackwell$d2006 215 $a1 online resource (478 p.) 300 $aDescription based upon print version of record. 311 $a0-7279-1773-0 320 $aIncludes bibliographical references and index. 327 $aAnaesthesia Science; Contents; List of Contributors; Preface; Part 1: Pharmacology; 1 Pharmacokinetic principles; 2 Pharmacodynamics; 3 Pharmacogenomics; 4 Receptors and second messenger systems; 5 Anaphylaxis; 6 Reflections on chirality; 7 Ion channels; 8 Immunosuppression; 9 Mechanisms of anaesthesia: a role for voltage-gated K channels?; 10 Use and abuse of antibiotics; Part 2: Physiology; 11 Inflammation and immunity; 12 Shock: pathogenesis and pathophysiology; 13 Cellular physiology; 14 Acid-base balance: albumin and strong ions; 15 Fluids and electrolytes; 16 The microcirculation 327 $a17 Respiratory physiology at the molecular level18 Non-respiratory functions of the lung; 19 The brain as a site of inflammation after acute injury; 20 Heart failure; 21 The hormonal and metabolic response to anaesthesia, surgery and trauma; 22 Temperature regulation; 23 Theories of pain; 24 Neuromuscular transmission and function; Part 3: Clinical measurement; 25 Magnetic resonance imaging; 26 Nanotechnology; 27 Assessment of the cardiovascular system; 28 Assessment of respiratory function; 29 Monitoring the depth of anaesthesia; 30 Research study design; Index 330 $aAnaesthesia Science presents the scientific foundations upon which the clinical practice of anaesthesia and care of the critically ill are based. Written on the basis that basic science underlies the practice of anaesthesiaContributors include some of the world's most eminent anaesthesiologistsProvides coverage on less well appreciated aspects of the subject, such as the microcirculation, multi-organ failure, and the theory of painThoroughly integrates the clinical practice of anaesthesia with basic sciences, providing all the infor 606 $aAnesthesia 606 $aSurgery 615 0$aAnesthesia. 615 0$aSurgery. 676 $a617.9 676 $a617.96 701 $aWebster$b Nigel R$01343098 701 $aGalley$b Helen F$01343099 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830522003321 996 $aAnaesthesia science$93067122 997 $aUNINA