LEADER 05317nam 2200661 a 450 001 9910830505603321 005 20230802004513.0 010 $a1-118-34643-2 010 $a1-118-70284-0 010 $a1-283-45406-8 010 $a9786613454065 010 $a1-118-34642-4 035 $a(CKB)2550000000083736 035 $a(EBL)849018 035 $a(OCoLC)775302055 035 $a(SSID)ssj0000599672 035 $a(PQKBManifestationID)11410680 035 $a(PQKBTitleCode)TC0000599672 035 $a(PQKBWorkID)10596431 035 $a(PQKB)11737810 035 $a(OCoLC)785777951 035 $a(MiAaPQ)EBC849018 035 $a(EXLCZ)992550000000083736 100 $a20111019d2012 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aOral precancer$b[electronic resource] $ediagnosis and management of potentially malignant disorders /$fedited by Peter Thomson 210 $aChichester [England] $cWiley-Blackwell$d2012 215 $a1 online resource (237 p.) 300 $aDescription based upon print version of record. 311 $a1-4443-3574-X 320 $aIncludes bibliographical references and index. 327 $aORAL PRECANCER: DIAGNOSIS AND MANAGEMENT OF POTENTIALLY MALIGNANT DISORDERS; Contents; List of Contributors; Preface; Acknowledgements; 1 Introduction; General Introduction; Epidemiology; Prevalence of Oral Leukoplakia; Prevalence of Oral Erythroplakia; Prevention; Treatment Strategies; Terminology; Summary; References; 2 Form and Function of the Oral Mucosa; Introduction; Applied Anatomy of the Oral Cavity; Function of the Oral Mucosa; Microanatomy of the Oral Mucosa; Regional Variation of the Oral Mucosa; Oral Epithelial Cell Kinetics; Oral Epithelial Cell Proliferative Activity 327 $aAnatomical Site Predilection for Oral CarcinogenesisSummary; References; 3 Oral Carcinogenesis; Introduction; Oral Cancer and Precancer; The 'Progression Model' for Oral Cancer; Aetiology and Risk Factors; Patient and Risk Factor Profiling; Summary; References; 4 Clinical Presentation of Oral Precancer; Introduction; Clinical Terminology; Precancerous (Premalignant) Lesions; Precancerous (Premalignant) Conditions; Syphilis; Multiple Lesion Disease; Summary; References; 5 Diagnostic Methods; Introduction; Screening; Clinical Examination Techniques; Diagnostic Aids in Precancer Diagnosis 327 $aBrush Biopsy and Exfoliative CytologyClinical Diagnosis in Practice; Summary; References; 6 Pathological Aspects of Oral Precancer; Introduction; Biopsy Techniques; Role of the Pathologist; Histopathological Features of Oral Potentially Malignant Disorders; Grading of Dysplasia; Limitations in Conventional Pathological Techniques; Summary; References; 7 Management of Oral Precancer; Introduction; Risk Factor Modification; Observation Versus Intervention; Medical Treatment; Surgical Treatment; Combined Treatment Modalities; Patient Follow Up and Surveillance; Summary; References 327 $a8 Clinical OutcomeIntroduction; Clinical Outcome Studies; Patient Cohort Studies; Definitions of Clinical Outcome; Newcastle Patient Cohort Studies; Patient Follow Up; Prediction of Clinical Outcome; Summary; References; 9 Malignant Transformation and Oral Cancer Development; Introduction; Risk of Progression to Oral Carcinoma; Malignant Transformation Versus Oral Cancer Development; Interventional Laser Surgery and Oral Cancer Prevention; Newcastle 10-Year Follow-Up Study; High- and Low-Risk Patients; Clinical Signs of Oral Squamous Cell Carcinoma 327 $aDiagnosis and Management of 'Unexpected Malignancy'Prognosis for the 'Transformed' Patient; Summary; References; 10 The Future; Introduction; Prevention of Oral Precancer; Early Diagnosis of Potentially Malignant Disease; Interventional Management Strategies in the Future; Individualised Patient Treatments: Biomarkers and Targeted Chemoprevention; Future Research Directions; Summary; References; 11 Case Histories; Introduction; Case 1: Diagnosis of Unexpected Malignancy; Case 2: Multiple Lesion Disease Responding to Conservative Management 327 $aCase 3: Multiple Lesion Disease Requiring Repeated Laser Treatments 330 $a"Oral Precancer is a preeminent new book that compiles recent research on precancer conditions of the oral cavity and their specific application to the dental field. In addition to providing a scientific and evidence-based survey of the disparate sources of oral precancer research, this book presents practical information for dental practitioners. Written by a prominent researcher in the field, Oral Precancer furnishes its readers with a balanced approach to this highly topical subject"--Provided by publisher. 606 $aMouth$xPrecancerous conditions$xDiagnosis 606 $aMouth$xCancer$xDiagnosis 606 $aMouth$xCancer 615 0$aMouth$xPrecancerous conditions$xDiagnosis. 615 0$aMouth$xCancer$xDiagnosis. 615 0$aMouth$xCancer. 676 $a616.99/431 676 $a616.99431 701 $aThomson$b Peter$g(Peter James)$0167015 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830505603321 996 $aOral precancer$94119443 997 $aUNINA