LEADER 03458nam 22005894a 450 001 9910830500003321 005 20230721031252.0 010 $a1-281-06924-8 010 $a9786611069247 010 $a0-470-69197-2 010 $a0-470-76594-1 035 $a(CKB)1000000000413182 035 $a(EBL)320053 035 $a(OCoLC)476116407 035 $a(SSID)ssj0000117855 035 $a(PQKBManifestationID)11145431 035 $a(PQKBTitleCode)TC0000117855 035 $a(PQKBWorkID)10051304 035 $a(PQKB)11132353 035 $a(MiAaPQ)EBC320053 035 $a(EXLCZ)991000000000413182 100 $a20070207d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aCardiovascular genetics and genomics for the cardiologist$b[electronic resource] /$fedited by Victor J. Dzau, Choong-Chin Liew 210 $aMalden, Mass. $cBlackwell Futura$d2007 215 $a1 online resource (330 p.) 300 $aDescription based upon print version of record. 311 $a1-4051-3394-5 320 $aIncludes bibliographical references and index. 327 $aThe gene in the twenty-first century / Choong-Chin Liew, Victor J. Dzau -- Monogenic hypercholesterolemia / Ruth McPherson -- Hypertrophic cardiomyopathy / Ali J. Marian -- Dilated cardiomyopathy and other cardiomyopathies / Mitra Esfandiarei, Robert Yanagawa, Bruce M. McManus -- The long QT syndrome / Sabina Kupershmidt, Kamilla Kelemen, Tadashi Nakajima -- Atherosclerosis / Pa?ivi Pajukanta, Kiat Tsong Tan, Choong-Chin Liew -- Heart failure / Markus Meyer, Peter VanBuren -- The implications of genes on the pathogenesis, diagnosis and therapeutics of hypertension / Kiat Tsong Tan, Choong-Chin Liew -- Gene therapy for cardiovascular disease: inserting new genes, regulating the expression of native genes, and correcting genetic defects / Ion S. Jovin, Frank J. Giordano -- Stem cell therapy for cardiovascular disease / Emerson C. Perin, Guilherme V. Silva -- Pharmacogenetics and personalized medicine / Julie A. Johnson, Issam Zineh -- The potential of blood-based gene profiling for disease assessment / Steve Mohr, Choon-Chin Liew. 330 $aUntil recently, a modest knowledge of genetics was more than adequate for the daily practice of clinical cardiology, but advances in genetics and genomics are changing cardiovascular medicine in fundamental ways. The identification of the genetic basis of several forms of dyslipidemia, hypertension, diabetes, cardiomyopathies, and vascular diseases signalled the new importance of genetics in clinical medicine. In this timely volume, Drs. Dzau and Liew - both pioneers in the area - help cardiologists understand: how cardiovascular genetics may remodel the way cardiovascular medicine 606 $aCardiovascular system$xDiseases$xGenetic aspects 606 $aCardiovascular system$xMolecular aspects 606 $aGenomics 615 0$aCardiovascular system$xDiseases$xGenetic aspects. 615 0$aCardiovascular system$xMolecular aspects. 615 0$aGenomics. 676 $a616.1/042 676 $a616.1042 701 $aDzau$b Victor J$0873810 701 $aLiew$b Choong-Chin$0873811 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830500003321 996 $aCardiovascular genetics and genomics for the cardiologist$91950675 997 $aUNINA