LEADER 05174nam 2200649Ia 450 001 9910830429103321 005 20230721030834.0 010 $a1-281-37388-5 010 $a9786611373887 010 $a0-470-18116-8 010 $a0-470-18115-X 035 $a(CKB)1000000000403764 035 $a(EBL)343650 035 $a(SSID)ssj0000208012 035 $a(PQKBManifestationID)11175349 035 $a(PQKBTitleCode)TC0000208012 035 $a(PQKBWorkID)10240097 035 $a(PQKB)11379290 035 $a(MiAaPQ)EBC343650 035 $a(OCoLC)664606186 035 $a(EXLCZ)991000000000403764 100 $a20070813d2008 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 14$aThe naphthyridines$b[electronic resource] /$fD.J. Brown 210 $aHoboken, N.J. $cWiley$dc2008 215 $a1 online resource (448 p.) 225 1 $aThe chemistry of heterocyclic compounds ;$v63 300 $a"An Interscience publication." 311 $a0-471-75159-6 320 $aIncludes bibliographical references (p. 295-336) and index. 327 $aTHE NAPHTHYRIDINES; Contents; CHAPTER 1 PRIMARY SYNTHESES OF 1,5-NAPHTHYRIDINES; 1.1 From a Single Aliphatic Substrate; 1.2 From a Single Pyridine Substrate; 1.2.1 By Formation of the N1,C2-Bond; 1.2.2 By Formation of the C3,C4-Bond; 1.2.3 By Formation of the C4,C4a-Bond; 1.3 From a Pyridine Substrate with One Synthon; 1.3.1 Where the Synthon Supplies One Atom; 1.3.2 Where the Synthon Supplies Two Atoms; 1.3.3 Where the Synthon Supplies Three Atoms; 1.4 From a Pyridine Substrate and Two Synthons; 1.5 From Other Heterocyclic Substrates 327 $aCHAPTER 2 1,5-NAPHTHYRIDINE, ALKYL-1,5- NAPHTHYRIDINES, AND ARYL-1,5- NAPHTHYRIDINES2.1 1,5-Naphthyridine; 2.1.1 Preparation of 1,5-Naphthyridine; 2.1.2 Properties of 1,5-Naphthyridine; 2.1.3 Reactions of 1,5-Naphthyridine; 2.2 Alkyl- and Aryl-1,5-Naphthyridines; 2.2.1 Preparation of Alkyl- and Aryl-1,5-Naphthyridines; 2.2.2 Reactions of Alkyl- and Aryl-1,5-Naphthyridines; CHAPTER 3 HALOGENO-1,5-NAPHTHYRIDINES; 3.1 Preparation of Halogeno-1,5-Naphthyridines; 3.1.1 By Direct Halogenation; 3.1.2 By Halogenolysis of 1,5-Naphthyridinones or the Like 327 $a3.1.3 By the Meissenheimer Reaction on 1,5-Naphthyridine N-Oxides3.1.4 By Miscellaneous Procedures; 3.2 Reactions of Halogeno-1,5-Naphthyridines; 3.2.1 Alcoholysis or Phenolysis of Halogeno-1, 5-Naphthyridines; 3.2.2 Aminolysis of Halogeno-1,5-Naphthyridines; 3.2.3 Other Reactions of Halogeno-1,5-Naphthyridines; CHAPTER 4 OXY-1,5-NAPHTHYRIDINES; 4.1 Tautomeric 1,5-Naphthyridinones and Extranuclear Hydroxy-1,5-Naphthyridines; 4.1.1 Preparation of Tautomeric 1,5-Naphthyridinones and the Like; 4.1.2 Reactions of Tautomeric 1,5-Naphthyridinones and the Like 327 $a4.2 Alkoxy- and Aryloxy-1,5-Naphthyridines4.3 Nontautomeric 1,5-Naphthyridinones; 4.4 1,5-Naphthyridine N-Oxides; CHAPTER 5 THIO-1,5-NAPHTHYRIDINES; CHAPTER 6 NITRO-, AMINO-, AND RELATED 1,5-NAPHTHYRIDINES; 6.1 Nitro-1,5-Naphthyridines; 6.1.1 Preparation of Nitro-1,5-Naphthyridines; 6.1.2 Reactions of Nitro-1,5-Naphthyridines; 6.2 Amino- and (Substituted-Amino)-1,5-Naphthyridines; 6.2.1 Preparation of Amino-1,5-Naphthyridines; 6.2.2 Reactions of Amino-1,5-Naphthyridines; CHAPTER 7 1,5-NAPHTHYRIDINECARBOXYLIC ACIDS AND RELATED DERIVATIVES; 7.1 1,5-Naphthyridinecarboxylic Acids 327 $a7.2 1,5-Naphthyridinecarboxylic Esters7.3 1,5-Naphthyridinecarboxamides, Carbonitriles, Carbaldehydes, and Ketones; CHAPTER 8 PRIMARY SYNTHESES OF 1,6-NAPHTHYRIDINES; 8.1 By Condensation of Two or More Aliphatic Substrates/Synthons; 8.2 From a Single Pyridine Substrate; 8.3 From a Pyridine Substrate with One Synthon; 8.3.1 Where the Synthon Supplies One Ring Atom; 8.3.2 Where the Synthon Supplies Two Ring Atoms; 8.3.3 Where the Synthon Supplies Three or More Ring Atoms; 8.4 From a Pyridine Substrate with Two or More Synthons; 8.5 From Other Heterocyclic Systems 327 $aCHAPTER 9 1,6-NAPHTHYRIDINE, ALKYL-1,6- NAPHTHYRIDINES, AND ARYL-1,6- NAPHTHYRIDINES 330 $aA volume in the Chemistry of Heterocyclic Compounds series, this book provides a summary of the chemistry of each of the six naphthyridine systems along with tables of known simple derivatives with original references.Each of the six naphthyridine systems are described in valuable detail and coverage includes: Primary synthetic methods from non-naphthyridine substrates; Chemistry and properties of the parent heterocycle and its simple alkyl derivatives; Formation and reactions of halogeno derivatives; formation and reactions of hydroxy, oxo, alkoxy, and related derivatives. 410 0$aChemistry of heterocyclic compounds. 606 $aPyridine$xDerivatives 606 $aChemistry 615 0$aPyridine$xDerivatives. 615 0$aChemistry. 676 $a547.59 676 $a547/.59/05 676 $a547/.593 700 $aBrown$b D. J$0383088 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830429103321 996 $aThe naphthyridines$93995393 997 $aUNINA