LEADER 03952nam 2200673Ia 450 001 9910830425403321 005 20230721030215.0 010 $a1-282-12387-4 010 $a9786612123870 010 $a0-470-98557-7 010 $a0-470-98556-9 035 $a(CKB)1000000000377303 035 $a(EBL)470483 035 $a(SSID)ssj0000360016 035 $a(PQKBManifestationID)11244187 035 $a(PQKBTitleCode)TC0000360016 035 $a(PQKBWorkID)10317795 035 $a(PQKB)10624946 035 $a(MiAaPQ)EBC470483 035 $a(OCoLC)184983387 035 $a(EXLCZ)991000000000377303 100 $a20070626d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aFatty acids and lipotoxicity in obesity and diabetes$b[electronic resource] /$feditors: Gregory Bock and Jamie Goode 210 $aLondon $cJohn Wiley$d2007 215 $a1 online resource (223 p.) 225 1 $aNovartis Foundation symposium ;$v286 300 $aDescription based upon print version of record. 311 $a0-470-05764-5 320 $aIncludes bibliographical references and index. 327 $aFATTY ACIDS AND LIPOTOXICITY IN OBESITY AND DIABETES; Contents; Chair's introduction; Transcriptional control of energy homeostasis through the PGC1 coactivators; DISCUSSION; Human obesity and insulin resistance: lessons from experiments of nature; DISCUSSION; Lipid-induced metabolic dysfunction in skeletal muscle; DISCUSSION; Stearoyl-CoA desaturase deficiency, hypercholesterolaemia, cholestasis and diabetes; DISCUSSION; The role of lipin 1 in adipogenesis and lipid metabolism; DISCUSSION; The role of the AMP-activated protein kinase in the regulation of energy homeostasis; DISCUSSION 327 $aEndoplasmic reticulum stress and inflammation in obesity and type 2 diabetesDISCUSSION; The impact of insulin resistance on macrophage death pathways in advanced atherosclerosis; DISCUSSION; Fatty acid transport in adipocytes and the development of insulin resistance; DISCUSSION; Vectorial acylation: linking fatty acid transport and activation to metabolic trafficking; DISCUSSION; Lipid storage and mobilization pathways in yeast; DISCUSSION; Cide proteins and the development of obesity; DISCUSSION; General discussion I; Visualizing brown adipose tissue with FDG-PET 327 $aAdiponectin and adiponectin receptors in obesity-linked insulin resistanceDISCUSSION; Anti-inflammatory and antidiabetic roles of PPARy; DISCUSSION; Final Discussion; Nutrition, ageing and lipotoxicity; Contributor Index; Subject Index 330 $aThe potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure to high concentrations of free fatty acids in the blood affects pancreatic ß cell function, insulin secretion and lipid synthesis in the liver, and storage in adipose tissue. Maintaining the normal levels of fatty acids requires coordinated regulation between the liver, adipose tissue and skeletal muscle. This book deals with the molecular aspects of fatty acid action in obesity and insulin resistance. The topics in 410 0$aNovartis Foundation symposium ;$v286. 606 $aLipids$xMetabolism$vCongresses 606 $aFatty acids$vCongresses 606 $aAdipose tissues$vCongresses 606 $aObesity$vCongresses 606 $aDiabetes$vCongresses 615 0$aLipids$xMetabolism 615 0$aFatty acids 615 0$aAdipose tissues 615 0$aObesity 615 0$aDiabetes 676 $a612.397 701 $aBock$b Gregory$0322650 701 $aGoode$b Jamie$0283336 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830425403321 996 $aFatty acids and lipotoxicity in obesity and diabetes$94013865 997 $aUNINA LEADER 03719nam 22006495 450 001 9910865259103321 005 20240531140443.0 010 $a9789819967278 010 $a9819967279 024 7 $a10.1007/978-981-99-6727-8 035 $a(CKB)32200991800041 035 $a(MiAaPQ)EBC31359962 035 $a(Au-PeEL)EBL31359962 035 $a(DE-He213)978-981-99-6727-8 035 $a(MiAaPQ)EBC31788367 035 $a(Au-PeEL)EBL31788367 035 $a(EXLCZ)9932200991800041 100 $a20240531d2024 u| 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHandbook of Biomass /$fedited by Sabu Thomas, Mahesh Hosur, Daniel Pasquini, Cintil Jose Chirayil 205 $a1st ed. 2024. 210 1$aSingapore :$cSpringer Nature Singapore :$cImprint: Springer,$d2024. 215 $a1 online resource (1554 pages) 311 08$a9789819967261 311 08$a9819967260 327 $aIntroduction to different types of biomasses -- Composition and properties of Biomass -- Biomass Modifications -- Cellulose and Modifications -- Lignin and Modifications -- Hemicellulose and Modifications -- Pectin and Modifications -- Starch and Modifications -- Nanocellulose and Modifications -- Conversion Strategies for Biomass -- Biomass Valorization -- Science and Technology of Biomass -- Environmental and Sustainability aspects related to Biomass. 330 $aThis handbook constitutes state-of-the-art research covering topics such as chemical constituents of biomass, their specific properties, characterization and different applications. The contents also discuss challenges and issues involved in its applications. This volume brings together a number of biomass-derived potential renewable elements and its circular economy approach in one place. The content includes industrial applications and fills the gap in laboratory research works to practical applications in related industries. The book gives an insight towards the circular economy approach by the biomass, different gross morphologies of biomasses and the valuable chemical constituents that can be derived from the biomass and moreover the potential applications of all those constituents. It enables researchers and scientists to get informed of the designs to improve existing utilization of biomass in an efficient manner and deliver better products at lower cost. The volume isuseful reference for professionals, researchers, industrial practitioners, graduate students and senior undergraduates in the fields of polymer science, bioscience and bioengineering. It also provides an in-depth reference for biomass processors and fabricators and for industry sectors utilizing biomass such as packaging, sensors, film manufacturers, medical device manufacturers and biomedical engineers. 606 $aBiomaterials 606 $aBiopolymers 606 $aMaterials$xAnalysis 606 $aPlant Materials 606 $aBiopolymers 606 $aBiomaterials 606 $aMaterials Characterization Technique 615 0$aBiomaterials. 615 0$aBiopolymers. 615 0$aMaterials$xAnalysis. 615 14$aPlant Materials. 615 24$aBiopolymers. 615 24$aBiomaterials. 615 24$aMaterials Characterization Technique. 676 $a620.19 700 $aThomas$b Sabu$0851308 701 $aHosur$b Mahesh$01742560 701 $aPasquini$b Daniel$01742561 701 $aJose Chirayil$b Cintil$01742562 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910865259103321 996 $aHandbook of Biomass$94169308 997 $aUNINA