LEADER 03689oam 2200673zu 450 001 9910830411003321 005 20230617031157.0 010 $a1-280-55674-9 010 $a9786610556748 010 $a0-471-65642-9 010 $a0-471-65643-7 035 $a(CKB)1000000000018970 035 $a(SSID)ssj0000291095 035 $a(PQKBManifestationID)11232781 035 $a(PQKBTitleCode)TC0000291095 035 $a(PQKBWorkID)10249040 035 $a(PQKB)10788770 035 $a(MiAaPQ)EBC4957770 035 $a(Au-PeEL)EBL4957770 035 $a(CaONFJC)MIL55674 035 $a(OCoLC)85820209 035 $a(EXLCZ)991000000000018970 100 $a20160829d2004 uy 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aCell cycle and growth control : biomolecular regulation and cancer 205 $a2nd ed. 210 31$a[Place of publication not identified]$cWiley Liss$d2004 215 $a1 online resource (802 pages) 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a0-471-25071-6 330 $aThe groups of specialized cells that make up the various human tissues depend on an intricate communication network to regulate gene expression that in turn mediates growth, cell--type specific function, division, and programmed cell death. This network consists of extracellular signals interacting with the receptors of individual cells and determining the fate of each. Since this regulatory system plays a critical role in complex tissue, aberrations or malfunctions often accompany the onset and progression of cancer. Cell Cycle and Growth Control: Biomolecular Regulation and Cancer, Second Edition provides a solid basis for understanding cell cycle and growth control as it relates to biological regulation, with a special emphasis on examining these processes in the context of cancer.; Newly updated with the latest significant advances, this Second Edition features: Cutting--edge applications in clinical diagnostics and therapeutics Focus on mechanisms mediating the control of proliferation Numerous clear illustrations Extensive bibliography Well--recognized, expert chapter authors Video clips on accompanying Web site showing cell cycle control Cell Cycle and Growth Control, Second Edition offers both an introduction to important concepts and detailed discussion of regulatory mechanisms at the cellular, biochemical, genetic, and molecular levels. The only book to comprehensively cover both the foundations and cutting--edge advances in understanding cell cycle and growth control, this text also contains an expert perspective on innovative strategies for cancer treatment, making it a vital companion for researcher and clinician alike. 606 $aCell Cycle$xphysiology 606 $aMutagenesis$xphysiology 606 $aCell Death$xphysiology 606 $aCell Transformation, Neoplastic 606 $aGenomic Instability 606 $aCytology$2HILCC 606 $aBiology$2HILCC 606 $aHealth & Biological Sciences$2HILCC 615 12$aCell Cycle$xphysiology. 615 22$aMutagenesis$xphysiology. 615 22$aCell Death$xphysiology. 615 22$aCell Transformation, Neoplastic. 615 22$aGenomic Instability. 615 7$aCytology 615 7$aBiology 615 7$aHealth & Biological Sciences 676 $a571.84 702 $aPardee$b Arthur B$g(Arthur Beck),$f1921- 702 $aStein$b Gary S 801 0$bPQKB 906 $aBOOK 912 $a9910830411003321 996 $aCell cycle and growth control : biomolecular regulation and cancer$93916323 997 $aUNINA