LEADER 02743oam  2200601zu 450 
001 9910830341803321
005 20210721055542.0
010   $a9786610556120
010   $a0-470-86873-2
035   $a(CKB)111087027093264
035   $a(SSID)ssj0000161654
035   $a(PQKBManifestationID)11164483
035   $a(PQKBTitleCode)TC0000161654
035   $a(PQKBWorkID)10199616
035   $a(PQKB)10848549
035   $a(MiAaPQ)EBC5247714
035   $a(Au-PeEL)EBL5247714
035   $a(CaONFJC)MIL55612
035   $a(OCoLC)748537746
035   $a(EXLCZ)99111087027093264
100   $a20160829d2002      uy              
101 0 $aeng
135   $aurcnu||||||||
181   $ctxt
182   $cc
183   $acr
200 04$aThe genetics and biology of sex determination
210 31$a[Place of publication not identified]$cJohn Wiley$d2002
215   $a1 online resource (275 pages)
300   $aBibliographic Level Mode of Issuance: Monograph
311   $a0-470-84346-2 
330   $aNature employs a wide variety of sex determining mechanisms and it is only comparatively recently that the tools have become available for these to be explored at the cellular and molecular levels. A major landmark was the discovery in 1990 of the SRY gene and the subsequent demonstration of its key role in triggering male sex determination in transgenic mice. This book reviews and discusses our current understanding of the molecular genetic pathways of sex determination, with special emphasis on vertebrates. It features comparisons with other modes of sex determination, consideration of the biology of sexual development and discussion of the evolution of sex-determining mechanisms. By bringing together an international and interdisciplinary group of experts who study many different aspects of the problem, the book highlights much new and exciting work in this area and serves to identify and stimulate promising new research directions.
606   $aGenetic sex determination$vCongresses
606   $aSex Determination Processes
606   $aPhysiology$2HILCC
606   $aHuman Anatomy & Physiology$2HILCC
606   $aHealth & Biological Sciences$2HILCC
608   $aCongress.
615  0$aGenetic sex determination
615 12$aSex Determination Processes.
615  7$aPhysiology
615  7$aHuman Anatomy & Physiology
615  7$aHealth & Biological Sciences
676   $a571.882
702   $aGoode$b Jamie
702   $aNovartis Foundation
702   $aChadwick$b Derek
712 02$aNovartis Foundation
801  0$bPQKB
906   $aBOOK
912   $a9910830341803321
996   $aThe genetics and biology of sex determination$94084487
997   $aUNINA