LEADER 03113nam 22006134a 450 001 9910830339303321 005 20230721005143.0 010 $a1-282-03106-6 010 $a9786612031069 010 $a0-470-39961-9 010 $a0-470-39959-7 035 $a(CKB)1000000000719574 035 $a(EBL)427772 035 $a(OCoLC)321073601 035 $a(SSID)ssj0000252200 035 $a(PQKBManifestationID)11204900 035 $a(PQKBTitleCode)TC0000252200 035 $a(PQKBWorkID)10176759 035 $a(PQKB)10041516 035 $a(MiAaPQ)EBC427772 035 $a(EXLCZ)991000000000719574 100 $a20080815d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aStrategies for organic drug synthesis and design$b[electronic resource] /$fDaniel Lednicer 205 $a2nd ed. 210 $aHoboken, N.J. $cJohn Wiley & Sons$dc2009 215 $a1 online resource (702 p.) 300 $aDescription based upon print version of record. 311 $a0-470-19039-6 320 $aIncludes bibliographical references and indexes. 327 $aProstaglandins, peptidomimetic compounds, and retinoids -- Drugs based on a substituted benzene ring -- Indenes, naphthalenes, and other polycyclic aromatic compounds -- Steroids; pt. 1 : estranes, gonanes, and androstanes -- Steroids; pt. 2 : compounds related to progesterone, cortisone, and cholesterol -- Nonsteroidal sex hormones and their antagonists -- Opioid anagesics -- Drugs based on five-membered heterocycles -- Drugs based on six-membered heterocycles -- Five-membered heterocycles fused to a benzene ring -- Six-membered heterocycles fused to a benzene ring -- Seven-membered heterocycles fused to benzene -- Heterocyles fused to two aromatic rings -- Beta lactam antibiotics -- Heterocycles fused to other heterocyclic rings. 330 $aThis book examines and evaluates the strategies utilized to design and synthesize pharmaceutically active agents. Significant updates over the last 10 years since the publication of the 1st edition include synthesis of enantiomerically pure isomers, novel chemical methodologies, and new pharmaceutical agents targeted at novel biological endpoints. Written by an experienced successful author, this book meets the needs of a growing community of researchers in pharmaceutical R &D, as well as medical professionals, by providing a useful guide for designing and synthesizing pharmaceutical agents. A 606 $aPharmaceutical chemistry 606 $aDrugs$xSynthesis 606 $aDrugs$xDesign 606 $aOrganic compounds$xSynthesis 615 0$aPharmaceutical chemistry. 615 0$aDrugs$xSynthesis. 615 0$aDrugs$xDesign. 615 0$aOrganic compounds$xSynthesis. 676 $a615.19 676 $a615/.19 700 $aLednicer$b Daniel$f1929-$091622 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830339303321 996 $aStrategies for organic drug synthesis and design$9397248 997 $aUNINA