LEADER 03395nam 2200565 a 450 001 9910830264703321 005 20230213211647.0 010 $a1-280-76855-X 010 $a9786613679321 010 $a0-470-71901-X 010 $a0-470-71648-7 035 $a(CKB)1000000000687271 035 $a(EBL)703747 035 $a(SSID)ssj0000715146 035 $a(PQKBManifestationID)11472746 035 $a(PQKBTitleCode)TC0000715146 035 $a(PQKBWorkID)10700296 035 $a(PQKB)10932788 035 $a(MiAaPQ)EBC703747 035 $a(OCoLC)264621124 035 $a(EXLCZ)991000000000687271 100 $a19860103d1957 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aCiba Foundation Symposium on the Chemistry and Biology of Purines$b[electronic resource] /$feditors for the Ciba Foundation, G.E.W. Wolstenholme and Cecilia M. O'Connor 210 $aBoston $cLittle, Brown and Co.$d[1957] 215 $a1 online resource (350 p.) 225 1 $aCiba Foundation symposia 300 $aDescription based upon print version of record. 311 $a0-470-72244-4 320 $aIncludes bibliographical references and indexes. 327 $aCHEMISTRY AND BIOLOGY OF PURINES; CONTENTS; Opening remarks; Synthesis and properties of purines of potential biological interest; Discussion; Some synthetic studies on purines and related heterocycles; Discussion; Some new -N-methylpurines; The structure of the hydroxypurines investigated by O-and N-methylation; Discussion; The spectra and structure of the monohydroxypurines and other potentially tautomeric purines; Short Communication; The p-electron properties of purine calculated by the L.C.A.O. method; Discussion; The degradation of uric acid by water under pressure 327 $aThe 8-position in purines. The chemical and biological transformation of purines into pteridines Discussion; Cvclonucleosides; Discussion; Stereochemistry of nucleoside synthesis; Discussion; Synthetic chemical investigations related to the metabolism of purines; Discussion; The effects of potential antipurines on a purine-requiring strain of Escherichla coli; Discussion; The chemistry of new purines in the B12 series of vitamins; Biological and microbiological activity of purine analogues of vitamin B12; Discussion; Puromycin; Discussion 327 $aChemical and biological behaviours of 9-b-D-ribofuranosylpurine Discussion; On the activation of the one-carbon unit for the biosynthesis of purine nucleotides; The enzymatic synthesis of inosinic acid de novo; Discussion; Enzymic control of purines by xanthine oxidase; Discussion; The biological effects of 8-azapurines; Discussion; Biochemical effects of 6-mercaptopurine; Discussion; The use of 6-mercaptopurine in the treatment of leukemia; Discussion; General Discussion; Chairman's closing remarks 410 0$aCiba Foundation symposium. 606 $aPurines$vCongresses 615 0$aPurines 676 $a612.015 701 $aWolstenholme$b G. E. W$g(Gordon Ethelbert Ward)$063039 701 $aO'Connor$b Cecilia M$g(Cecilia Mary),$f1927-$0207754 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830264703321 996 $aCiba Foundation Symposium on the Chemistry and Biology of Purines$93004934 997 $aUNINA