LEADER 05430nam 2200673 a 450 001 9910830256103321 005 20170815112707.0 010 $a1-281-32026-9 010 $a9786611320263 010 $a0-470-98881-9 010 $a0-470-99424-X 035 $a(CKB)1000000000406020 035 $a(EBL)351323 035 $a(OCoLC)476171686 035 $a(SSID)ssj0000216103 035 $a(PQKBManifestationID)11184955 035 $a(PQKBTitleCode)TC0000216103 035 $a(PQKBWorkID)10194029 035 $a(PQKB)11593043 035 $a(MiAaPQ)EBC351323 035 $a(PPN)242545505 035 $a(EXLCZ)991000000000406020 100 $a20060707d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aOrganic reactions in water$b[electronic resource] $eprinciples, strategies and applications /$fedited by U. Marcus Lindstro?m 210 $aOxford ;$aAmes, Iowa $cBlackwell Pub.$d2007 215 $a1 online resource (424 p.) 300 $aDescription based upon print version of record. 311 $a1-4051-3890-4 320 $aIncludes bibliographical references and indexes. 327 $aOrganic Reactions in Water : Principles, Strategies and Applications; Contents; Contributors; Preface; Foreword; 1 A Fifty-Year Perspective on Chemistry in Water; 1.1 Enzyme mimics and models; 1.1.1 Thiamine; 1.1.2 Cyclodextrins; 1.1.3 Cyclodextrins with bound metal ions; 1.1.4 Cyclodextrin dimers; 1.1.5 Ribonuclease mimics; 1.1.6 Transaminase mimics; 1.1.7 Cytochrome P-450 mimics; 1.2 Reactions in water promoted by hydrophobic binding of small molecules; 1.2.1 Diels-Alder reactions; 1.2.2 The benzoin condensation; 1.2.3 Atom transfer reactions 327 $a1.3 Quantitative antihydrophobic effects in water and the geometries of transition states1.4 The importance of water as a reaction solvent; References; 2 Structure and Properties of Water; 2.1 Water, the molecule and the liquid; 2.1.1 The single water molecule; 2.1.2 Liquid water; 2.2 Properties of water; 2.2.1 Solvent properties and parameters; 2.2.2 Thermodynamics of hydration; 2.2.3 Hydrophobic interactions; 2.3 Kinetic solvent effects in aqueous solution; References; 3 Acid Catalysis in Water; 3.1 Homogeneous catalysis; 3.1.1 Bronsted acid catalysis; 3.1.2 Lewis acid catalysis 327 $a3.1.3 Asymmetric catalysis3.2 Heterogeneous catalysis; 3.2.1 Polymer-supported Bronsted catalysis; 3.2.2 Polymer-supported metal catalysis; 3.3 Micellar catalysis; 3.3.1 LASC (Lewis acid-surfactant-combined catalysts); 3.3.2 BASC (Bronsted acid-surfactant-combined catalyst); 3.4 Conclusion; References; 4 Metal-Mediated C-C Bond Formations in Aqueous Media; 4.1 Introduction; 4.2 Reactivity of organometallic compounds with water; 4.2.1 C-M bonding; 4.2.2 C-M hydrolysis; 4.2.3 C M-reactions; 4.2.4 C-C bond formations via C-M reactions in water; 4.3 Allylation of carbonyls and imines 327 $a4.3.1 Alyllation of carbonyl compounds4.3.2 Allylation of imines and related compounds; 4.4 Propargylation/allenylation of carbonyls, imines, and related compounds; 4.5 Metal-mediated benzylation of carbonyls and imines; 4.6 Arylation and vinylation of carbonyls and imines; 4.6.1 Arylation and vinylation of aldehydes; 4.6.2 Arylation and vinylation of imines and related compounds; 4.7 Alkynylation of carbonyls, imines, and related compounds; 4.7.1 Alkynylation of aldehydes; 4.7.2 Alkynylation of imines and related compounds; 4.7.3 Asymmetric alkynylation 327 $a4.8 Metal-mediated aldol and Reformatsky-type reactions4.9 Metal-mediated alkylation of carbonyls and imines; 4.9.1 Alkylation of aldehydes; 4.9.2 Alkylation of imines; 4.10 Metal-mediated conjugate addition reactions; 4.10.1 Addition of alkyl groups; 4.10.2 Addition of vinyl and aryl groups; 4.10.3 Addition of alkynes; 4.11 Metal-mediated coupling reactions; 4.11.1 Pinacol coupling; 4.11.2 Other reductive couplings; 4.11.3 Cross-dehydrogenative coupling; 4.12 Conclusion; References; 5 Pericyclic Reactions in Aqueous Media; 5.1 Diels-Alder cycloaddition reactions 327 $a5.1.1 Carbo Diels-Alder reactions 330 $aVolatile organic solvents are the normal media used in both research scale and industrial scale synthesis of organic chemicals. Their environmental impact is significant, however, and so the development of alternative reaction media has become of great interest.Developments in the use of water as a solvent for organic synthesis have reached the point where it could now be considered a viable solvent for many organic reactions. Organic Reactions in Water demonstrates the underlying principles of using water as a reaction solvent and, by reference to a range of reaction types and systems 606 $aWater chemistry 606 $aSolvents$xEnvironmental aspects 606 $aOrganic compounds$xSynthesis$xEnvironmental aspects 615 0$aWater chemistry. 615 0$aSolvents$xEnvironmental aspects. 615 0$aOrganic compounds$xSynthesis$xEnvironmental aspects. 676 $a547.2 676 $a547/.2 686 $a35.52$2bcl 686 $a35.51$2bcl 701 $aLindstro?m$b U. Marcus$g(Ulf Marcus),$f1971-$0881315 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830256103321 996 $aOrganic reactions in water$91968244 997 $aUNINA