LEADER 04755nam 2200649 450 001 9910830245703321 005 20190715152939.0 010 $a1-282-02171-0 010 $a9786612021718 010 $a3-527-62521-6 010 $a3-527-62522-4 035 $a(CKB)1000000000577977 035 $a(EBL)482075 035 $a(SSID)ssj0000298178 035 $a(PQKBManifestationID)11223412 035 $a(PQKBTitleCode)TC0000298178 035 $a(PQKBWorkID)10361737 035 $a(PQKB)10431107 035 $a(MiAaPQ)EBC482075 035 $a(PPN)15233999X 035 $a(OCoLC)299043628 035 $a(EXLCZ)991000000000577977 100 $a20160815h20092009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aHandbook of GC/MS $efundamentals and applications /$fHans-Joachim Hu?bschmann 205 $a2nd ed. 210 1$aWeinheim, [Germany] :$cWiley-VCH Verlag GmbH & Co. KGaA,$d2009. 210 4$d©2009 215 $a1 online resource (739 p.) 300 $aDescription based upon print version of record. 311 $a3-527-31427-X 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aHandbook of GC/MS; Foreword; Preface to the Second Edition; Preface to the First Edition; Contents; 1 Introduction; 2 Fundamentals; 2.1 Sample Preparation; 2.1.1 Solid Phase Extraction; 2.1.1.1 Solid Phase Microextraction; 2.1.2 Supercritical Fluid Extraction; 2.1.3 Pressurized Fluid Extraction; 2.1.4 Online Liquid Chromatography Clean-up; 2.1.5 Headspace Techniques; 2.1.5.1 Static Headspace Technique; 2.1.5.2 Dynamic Headspace Technique (Purge and Trap); 2.1.5.3 Headspace versus Purge and Trap; 2.1.6 Adsorptive Enrichment and Thermodesorption; 2.1.6.1 Sample Collection; 2.1.6.2 Calibration 327 $a2.2.3.4 Cold Injection Systems2.2.3.5 Injection Volumes; 2.2.3.6 On-column Injection; 2.2.3.7 Cryofocusing; 2.2.4 Capillary Columns; 2.2.4.1 Sample Capacity; 2.2.4.2 Internal Diameter; 2.2.4.3 Film Thickness; 2.2.4.4 Column Length; 2.2.4.5 Adjusting the Carrier Gas Flow; 2.2.4.6 Properties of Stationary Phases; 2.2.5 Chromatography Parameters; 2.2.5.1 The Chromatogram and its Meaning; 2.2.5.2 Capacity Factor k ?; 2.2.5.3 Chromatographic Resolution; 2.2.5.4 Factors Affecting the Resolution; 2.2.5.5 Maximum Sample Capacity; 2.2.5.6 Peak Symmetry; 2.2.5.7 Optimisation of Flow 327 $a2.2.6 Classical Detectors for GC/MS Systems2.2.6.1 FID; 2.2.6.2 NPD; 2.2.6.3 ECD; 2.2.6.4 PID; 2.2.6.5 ELCD; 2.2.6.6 FPD; 2.2.6.7 PDD; 2.2.6.8 Connection of Classical Detectors Parallel to the Mass Spectrometer; 2.3 Mass Spectrometry; 2.3.1 Resolving Power and Resolution in Mass Spectrometry; 2.3.1.1 High Resolution; 2.3.1.2 Unit Mass Resolution; 2.3.1.3 High and Low Resolution in the Case of Dioxin Analysis; 2.3.2 Time-of-Flight Analyser; 2.3.3 Isotope Ratio Monitoring GC/MS; 2.3.4 Ionisation Procedures; 2.3.4.1 Electron Impact Ionisation; 2.3.4.2 Chemical Ionisation 327 $a2.3.5 Measuring Techniques in GC/MS2.3.5.1 Detection of the Complete Spectrum (Full Scan); 2.3.5.2 Recording Individual Masses (SIM/MID); 2.3.5.3 High Resolution Accurate Mass MID Data Acquisition; 2.3.6 MS/MS -Tandem Mass Spectrometry; 2.3.7 Mass Calibration; 2.4 Special Aspects of GC/MS Coupling; 2.4.1 Vacuum Systems; 2.4.2 GC/MS Interface Solutions; 2.4.2.1 Open Split Coupling; 2.4.2.2 Direct Coupling; 2.4.2.3 Separator Techniques; References for Chapter 2; 3 Evaluation of GC/MS Analyses; 3.1 Display of Chromatograms; 3.1.1 Total Ion Current Chromatograms; 3.1.2 Mass Chromatograms 327 $a3.2 Substance Identification 330 $aThis is the first comprehensive reference work for GC/MS now in its second edition.It offers broad coverage, from sample preparation to the evaluation of MS-Data, including library searches. Fundamentals, techniques, and applications are described.A large part of the book is devoted to numerous examples for GC/MS-applications in environmental, food, pharmaceutical and clinical analysis. These proven examples come from the daily practice of various laboratories.The book also features a glossary of terms and a substance index that helps the reader to find information for his particul 606 $aGas chromatography 606 $aMass spectrometry 615 0$aGas chromatography. 615 0$aMass spectrometry. 676 $a543.85 676 $a543/.85 700 $aHu?bschmann$b Hans-Joachim$0724432 712 02$aWiley Online Library (Servicio en línea) 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830245703321 996 $aHandbook of GC$91419266 997 $aUNINA