LEADER 02974nam 2200565Ia 450 001 9910830234203321 005 20230617004721.0 010 $a9786610213375 010 $a1-280-21337-X 010 $a1-4443-0550-6 010 $a1-4051-4803-9 035 $a(CKB)1000000000342112 035 $a(EBL)238447 035 $a(OCoLC)144673944 035 $a(SSID)ssj0000240834 035 $a(PQKBManifestationID)11174168 035 $a(PQKBTitleCode)TC0000240834 035 $a(PQKBWorkID)10266441 035 $a(PQKB)11652064 035 $a(MiAaPQ)EBC238447 035 $a(EXLCZ)991000000000342112 100 $a20031107d2004 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aSample preparation for hyphenated analytical techniques$b[electronic resource] /$fedited by J.M. Rosenfeld 210 $aOxford $cBlackwell$d2004 215 $a1 online resource (237 p.) 300 $aDescription based upon print version of record. 311 $a0-8493-2374-6 311 $a1-4051-1106-2 320 $aIncludes bibliographical references and index. 327 $aContributors; Contents; 1 Introduction: current techniques and issues in sample preparation; 2 Molecular pathology: applications of genomic analyses to diagnosis of genetic diseases; 3 Measurement of oxidative DNA damage by gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry; 4 Utility of chemical derivatization schemes for peptide mass fingerprinting; 5 Oligosaccharides; 6 Hyphenated techniques in drug discovery: purity assessment, purification, quantitative analysis and metabolite identification; 7 Environmental organic analytes 327 $a8 From cells to instrumental analysis9 Studies on animal to instrument hyphenation: development of separation-based sensors for near real-time monitoring of drugs and neurotransmitters; Index 330 $aLinking "standard" but often mutually incompatible analytical techniques - so called hyphenation - generally leads to enhanced analytical performance, so hyphenated techniques are widely used in areas where samples are presented in complex matrices, eg environmental, pharmaceutical and biochemical analysis. With these hyphenated techniques, sample preparation is often the most time-consuming step in analysis, particularly where compounds are present in low concentration, and it has a huge influence on the quality of the analytical results. Sample preparation is still not given the importance i 606 $aSample introduction (Chemistry) 606 $aChemistry 615 0$aSample introduction (Chemistry) 615 0$aChemistry. 676 $a543.19 701 $aRosenfeld$b J. M$0969035 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830234203321 996 $aSample preparation for hyphenated analytical techniques$92201513 997 $aUNINA