LEADER 04154nam 22006974a 450 001 9910830228203321 005 20230617024559.0 010 $a1-280-27178-7 010 $a9786610271788 010 $a0-470-66888-1 010 $a0-470-86423-0 010 $a0-470-86797-3 035 $a(CKB)111087027094328 035 $a(EBL)158135 035 $a(SSID)ssj0000259662 035 $a(PQKBManifestationID)11204519 035 $a(PQKBTitleCode)TC0000259662 035 $a(PQKBWorkID)10186800 035 $a(PQKB)10978380 035 $a(MiAaPQ)EBC158135 035 $a(OCoLC)264389625 035 $a(EXLCZ)99111087027094328 100 $a20030107d2003 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aTissue engineering of cartilage and bone$b[electronic resource] /$f[editors, Gregory Bock, Jamie Goode] 210 $aChichester, West Sussex ;$aHoboken, NJ $cJ. Wiley$d2003 215 $a1 online resource (263 p.) 225 1 $aNovartis Foundation symposium ;$v249 300 $aDescription based upon print version of record. 311 $a0-470-84481-7 320 $aIncludes bibliographical references and index. 327 $aTISSUE ENGINEERING OF CARTILAGE AND BONE; Contents; Participants; Chair's introduction; Tissue engineering of cartilage: do we need it, can we do it, is it good and can we prove it?; Discussion; Embryonic development and the principles of tissue engineering; Discussion; The fundamentals of tissue engineering: scaffolds and bioreactors; Discussion; Tissue-engineered versus native cartilage: linkage between cellular mechano-transduction and biomechanical properties; Discussion; From the preclinical model to the patient; Discussion; Mesenchymal stem cell therapy in joint disease; Discussion 327 $aDifferentiated chondrocytes for cartilage tissue engineeringDiscussion; Mesenchymal stem cells and bioceramics: strategies to regenerate the skeleton; Discussion; Bone marrow stromal cells and their use in regenerating bone; Discussion; Studying the effect of different macrostructures on in vitro cell behaviour and in vivo bone formation using a tissue engineering approach; General discussion I; Cartilage repair with chondrocytes: clinical and cellular aspects; Discussion; Qualitative and quantitative in vivo assessment of articular cartilage using magnetic resonance imaging; Discussion 327 $aHyaluronan-based scaffolds (Hyalograft® C) in the treatment of knee cartilage defects: preliminary clinical findingsQuantitative analysis of repair tissue biopsies following chondrocyte implantation; Discussion; General discussion II Tissue engineering using recombinant human BMP2; Final discussion and summing-up; Index of contributors; Subject index 330 $aTissue engineering takes advantages of the combined use of cultured living cells and three-dimensional scaffolds to reconstruct adult tissues that are absent or malfunctioning. This book brings together scientists and clinicians working on a variety of approaches for regenerating of damaged or lost cartilage and bone to assess the progress of this dynamic field.In its early days, tissue engineering was driven by material scientists who designed novel bio-resorbable scaffolds on which to seed cells and grow tissues. This ground-breaking work generated high expectations, but there have b 410 0$aNovartis Foundation symposium ;$v249. 606 $aBone regeneration 606 $aJoints$xDiseases 606 $aCartilage$xDiseases 606 $aAnimal cell biotechnology 606 $aTissue culture 615 0$aBone regeneration. 615 0$aJoints$xDiseases. 615 0$aCartilage$xDiseases. 615 0$aAnimal cell biotechnology. 615 0$aTissue culture. 676 $a611.018 676 $a617.4/72 701 $aBock$b Gregory$0322650 701 $aGoode$b Jamie$0283336 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830228203321 996 $aTissue engineering of cartilage and bone$94021245 997 $aUNINA