LEADER 05357nam 2200661Ia 450 001 9910830202103321 005 20211109143541.0 010 $a1-68367-128-7 010 $a1-283-03441-7 010 $a9786613034410 010 $a1-61344-262-9 010 $a1-55581-682-7 035 $a(CKB)2670000000077760 035 $a(EBL)676285 035 $a(SSID)ssj0000485763 035 $a(PQKBManifestationID)11316193 035 $a(PQKBTitleCode)TC0000485763 035 $a(PQKBWorkID)10604827 035 $a(PQKB)10833720 035 $a(MiAaPQ)EBC676285 035 $a(PPN)194622843 035 $a(EXLCZ)992670000000077760 100 $a20100111d2010 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aManual of industrial microbiology and biotechnology$b[electronic resource] /$feditors in chief, Richard H. Baltz, Julian E. Davies, Arnold L. Demain ; editors, Alan T. Bull ... [et al.] 205 $a3rd ed. 210 $aWashington, DC $cASM Press$d2010 215 $a1 online resource (786 p.) 300 $aDescription based upon print version of record. 311 $a1-55581-512-X 320 $aIncludes bibliographical references and indexes. 327 $aCONTENTS; Editors /; Contributors /; Preface /; SECTION 1 ____________________________; ISOLATION AND SCREENING FOR SECONDARY METABOLITES AND ENZYMES /; Isolation; 1. New Approaches to Microbial Isolation /; 2. Selectie Isolation of Actinobacteria /; Identity/Dereplication; 3. Taxonomic Characterization of Prokaryotic Microorganisms /; Screening; 4. Enzymes from Extreme Environments /; 5. Cell-Based Screening Methods for Anti-Infective Compounds /; 6. Metabolomics for the Discovery of Novel Compounds /; 7 Strategies for Accessing Microbial Secondary Metabolites / 327 $aSection II ________________________FERMENTATION AND CELL CULTURE /; 8. Miniaturization of Fermentations /; 9. Solid-Phase Fermentation: Aerobic and Anaerobic /; 10. Bacterial Cultivation for Production of Proteins and Other Biological Products /; 11. Heterologous Protein Expression in Yeasts and Filamentous Fungi; 12. Mammalian Cell Culture for Biopharmaceutical Production /; 13. Manufacture of Mammalian Cell Biopharmaceuticals /; 14. Plant Cell Culture /; 15. Insect Cell Culture /; Section III; GENETICS, STRAIN IMPROVEMENT, AND RECOMBINANT PROTEINS / 327 $a16. Genetic Engineering of Corynebacteria /17. Genetic Manipulation of Clostridium /; 18. Genetic Manipulation of Myxobacteria /; 19. Strain Improvement of Escherichia coli To Enhance Recombinant Protein Production /; 20. Genetic Engineering Tools for Saccharomyces cerevisiae /; 21 Protein Expression in Nonconventional Yeasts /; 22. Genetics, Genetic Manipulation, and Approaches to Strain Improvement of Filamentous Fungi /; 23. Genetic Manipulation of Mammalian Cells for Protein Expression /; Section IV ___________________________________; GENETIC ENGINEERING OF SECONDARY METABOLITE SYNTHESIS 327 $a24. Glycosylation of Secondary Metabolites To Produce Novel Compounds /25. Metabolic Engineering of Escherichia coli for the Production of a Precursor to Artemisinin, an Antimalarial Drug /; 26. Heterologous Production of Polyketides in Streptomyces coelicolor and Escerichia coli /; 27. Genetic Engineering of Acidic Lipopeptide Antibiotics /; 28. Genetic Engineering To Regulate Production of Secondary Metabolites in Streptomyces clavuligerus /; 29. Genetic Engineering of Myxobacterial Natural Product Biosynthetic Genes /; Section V _______________________________________ 327 $aTRIAL ENZYMES, BIOCATALYSIS, AND ENZYME EVOLUTION /30. Tools for Enzyme Discovery /; 31. Enzyme Engineering: Combining Computational Approaches with Directed Evolution /; 32. Enzyme Engineering by Directed Evolution; 33. Industrial Applications of Enzymes as Catalysts /; 34. Biomass-Conerting Enzymes and Their Bioenergy Applications /; 35. The Use of Enzymes for Nonaqueous Organic Transformations /; 36. Enzyme Promiscuity and Evolution of New Protein Functions; 37. Enzyme Production in Escherichia coli; 38. Bioprocess Development /; Section VI _______________________________________ 327 $aMICROBIAL FUELS (BIOFUELS) AND FINE CHEMICALS / 330 $aThe third edition reviews the newest techniques, approaches, and options in the use of microorganisms and other cell culture systems for the manufacture of pharmaceuticals, industrial enzymes and proteins, foods and beverages, fuels and fine chemicals, and other products. Readers will find a rich array of methods and discussions of productive microbial processes, with means for improving the organism, the process, and the product. 606 $aBiotechnology$vHandbooks, manuals, etc 606 $aIndustrial microbiology$vHandbooks, manuals, etc 615 0$aBiotechnology 615 0$aIndustrial microbiology 676 $a660.6/2 701 $aBaltz$b Richard H$0112024 701 $aDavies$b Julian E$067143 701 $aDemain$b A. L$g(Arnold L.),$f1927-$067144 712 02$aAmerican Society for Microbiology. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830202103321 996 $aManual of industrial microbiology and biotechnology$94082556 997 $aUNINA