LEADER 01851nam 2200457 450 001 9910830186503321 005 20230606134442.0 010 $a1-119-56765-3 010 $a1-119-56764-5 010 $a1-119-56762-9 035 $a(MiAaPQ)EBC6886049 035 $a(Au-PeEL)EBL6886049 035 $a(CKB)21167526300041 035 $a(PPN)262311089 035 $a(EXLCZ)9921167526300041 100 $a20220928d2022 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aSpiro compounds $esynthesis and applications /$fedited by Ramon Rios Torres 210 1$aHoboken, New Jersey :$cJohn Wiley & Sons,$d[2022] 210 4$d©2022 215 $a1 online resource (461 pages) 311 08$aPrint version: Rios Torres, Ramon Spiro Compounds Newark : John Wiley & Sons, Incorporated,c2022 9781119567639 330 $a"Spirocycles are important structural elements due their unique properties. The major characteristics of spiro scaffolds are thire structural complexity and rigidity, favorable features in medicinal chemistry optimization programs against selected targets. The inherent challenges and the utility in drug discovery of these compounds have attracted the attention of several research groups that made huge steps in the development of new methodologies for their synthesis"--$cProvided by publisher. 606 $aOrganic compounds 606 $aSíntesi orgànica$2thub 608 $aLlibres electrònics$2thub 615 0$aOrganic compounds. 615 7$aSíntesi orgànica 676 $a543.62 702 $aRi?os Torres$b Ramo?n 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830186503321 996 $aSpiro compounds$93935021 997 $aUNINA