LEADER 03243nam 2200529 450 001 9910136584103321 035 $a(CKB)3710000000903214 035 $a(EBC)4717915 035 $a(OCoLC)962195173 035 $a(CaBNvSL)swl00406910 035 $a(MiAaPQ)EBC4717915 035 $a(EXLCZ)993710000000903214 100 $a20161105d2017 fy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 10$aNerve disease ALS and gradual loss of muscle function $eamytrophic lateral sclerosis /$fMary E. Miller 205 $aFirst edition. 210 1$aNew York, [New York] (222 East 46th Street, New York, NY 10017) :$cMomentum Press,$d2017. 215 $a1 online resource (xiii, 39 pages) $cillustrations 225 1 $aHuman diseases and conditions collection 320 $aIncludes bibliographical references (pages 27-29) and index. 327 $a1. Symptoms and diagnosis -- 2. Causes and contributing factors -- 3. Treatment and therapy -- 4. Future prospects -- Conclusion -- Bibliography -- Glossary -- About the author -- Index. 330 3 $aAmyotrophic lateral sclerosis, ALS, is a common form of motor neuron disease that involves a loss of function in upper and lower motor neurons. ALS causes a progressive loss of muscle function that frequently initiates in the limbs, called limb-onset ALS, or initiates in facial muscles, called bulbar-onset ALS. This book describes the current understanding of ALS symptoms, diagnosis, causes, and treatments. Initial symptoms vary in type of muscle dysfunction, intensity of symptoms, and speed of disease progression. Diagnosis requires loss of function in both upper and lower motor neurons for limb- and bulbar-onset ALS, distinguishing ALS from other neuromuscular diseases. Although no cause or initial trigger has been determined for ALS, eventually both limb and bulbar muscles will show dysfunction as the disease progresses. In later stages of the disease, muscle dysfunction typically leads to respiratory failure and death. Management of neurotransmitter levels in patients can prolong life by months, but no cure exits for the disease. Other treatments exist that can help patients manage muscle weakness or spasms as the disease progresses. The book concludes by considering future detection, treatment, and diagnostic approaches with the goal of preventing disease initiation or progression. 410 0$aHuman diseases and conditions collection. 606 $aAmyotrophic lateral sclerosis 606 $aAmyotrophic Lateral Sclerosis 608 $aLibros electronicos. 610 $aamyotrophic lateral sclerosis (ALS) 610 $aLou Gehrig's disease 610 $amotor neuron disease 610 $aneuromuscular junction 610 $alimb-onset ALS 610 $abulbar-onset ALS 610 $amuscle weakness 615 0$aAmyotrophic lateral sclerosis. 615 2$aAmyotrophic Lateral Sclerosis. 676 $a616.83 700 $aMiller$b Mary E.$0940760 801 0$bFINmELB 801 1$bFINmELB 906 $aBOOK 912 $a9910136584103321 996 $aNerve disease ALS and gradual loss of muscle function$92121485 997 $aUNINA LEADER 05193nam 2200637Ia 450 001 9910830172003321 005 20230721005752.0 010 $a1-282-68545-7 010 $a9786612685453 010 $a0-470-61186-3 010 $a0-470-61040-9 035 $a(CKB)2550000000005896 035 $a(EBL)477685 035 $a(OCoLC)609853571 035 $a(SSID)ssj0000354221 035 $a(PQKBManifestationID)11256484 035 $a(PQKBTitleCode)TC0000354221 035 $a(PQKBWorkID)10302775 035 $a(PQKB)11464694 035 $a(MiAaPQ)EBC477685 035 $a(EXLCZ)992550000000005896 100 $a20090424d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aFrom speech physiology to linguistic phonetics$b[electronic resource] /$fAlain Marchal 210 $aHoboken, NJ $cJohn Wiley & Sons, Inc. $cISTE Ltd$d2009 215 $a1 online resource (229 p.) 225 1 $aISTE ;$vv.145 300 $aDescription based upon print version of record. 311 $a1-84821-113-9 320 $aIncludes bibliographical references and index. 327 $aFrom Speech Physiology to Linguistic Phonetics; Table of Contents; Preface; Chapter 1. Respiration and Pulmonary Initiation; 1.1. The rib cage; 1.2. Lungs; 1.3. Normal respiration; 1.3.1. Inhalation; 1.3.2. Exhalation; 1.4. Respiration muscles; 1.4.1. Inhalation muscles; 1.4.2. Exhalation muscles; 1.5. Pulmonary capacity and pulmonary volume; 1.6. Respiration in phonation; 1.6.1. The respiratory cycle; 1.6.2. Control of exhalation; 1.6.3. Subglottal pressure; 1.6.4. Subglottal pressure and stress; Chapter 2. Phonation and the Larynx; 2.1. The larynx 327 $a2.1.1. External configuration of the larynx2.1.2. Internal configuration; 2.2. The laryngeal cartilages; 2.2.1. The cricoid cartilage; 2.2.2. The thyroid cartilage; 2.2.3. The arytenoid cartilages; 2.2.4. The epiglottic cartilage; 2.3. Joints and ligaments; 2.3.1. Intrinsic joints and ligaments; 2.3.2. The membranes and the extrinsic ligaments; 2.4. The larynx muscles; 2.4.1. The intrinsic muscles; 2.4.2. The extrinsic muscles; 2.5. Innervation of the larynx; 2.6. The mucous membrane of the larynx; 2.7. Phonation; 2.7.1. Opening and closing of the glottis; 2.7.2. Vocal fold vibration 327 $a2.7.3. Voice registers2.7.4. Head voice?; 2.7.5. Efficiency of the vocal generator; 2.7.6. The evaluation of phonation: voice quality; 2.8. The linguistic functions of laryngeal activity; 2.8.1. Glottal states and phonation types; 2.8.2. Tone and intonation; 2.8.3. Glottal articulation; 2.9. Phonetic features; Chapter 3. Articulation: Pharynx and Mouth; 3.1. The oral cavity; 3.1.1. The tongue; 3.1.2. Tongue control; 3.2. The pharynx; 3.2.1. The rhino-pharynx; 3.2.2. The hypopharynx and the oropharynx; 3.2.3. The role of the pharynx in speech 327 $aChapter 4. Articulation: The Labio-Mandibular System4.1. The lips: anatomical and functional description; 4.1.1. Lip closure; 4.1.2. Lip protrusion; 4.1.3. Lip rounding; 4.1.4. Raising the upper lip; 4.1.5. Lowering the lower lip; 4.1.6. Lip spreading; 4.1.7. Lowering the corners of the mouth; 4.1.8. Raising the corners of the mouth; 4.2. The jaw; 4.2.1. Muscles of the lower jaw; 4.2.2. The suprahyoid muscles; 4.3. Linguistic functions of lip movement; 4.3.1. Vowels; 4.3.2. Consonants; 4.4. Motor coordination between the lips and the lower jaw; Chapter 5. Elements of Articulatory Typology 327 $a5.1. Aerodynamic mechanisms5.1.1. Pulmonary initiation; 5.1.2. The larynx; 5.1.3. The supralaryngeal articulators; 5.2. Phonatory modes; 5.2.1. Voicing or modal voice; 5.2.2. Voicelessness; 5.2.3. Breathy mode; 5.2.4. The murmur; 5.2.5. Laryngealization or "creaky" mode; 5.2.6. Whisper mode; 5.2.7. Glottal closure; 5.3. Articulation; 5.3.1. The dimensions of the articulatory description of speech sounds; Chapter 6. The Articulatory Description of Vowels and Consonants; 6.1. Vowels; 6.1.1. Mode; 6.1.2. Articulatory region/zone; 6.1.3. Vocalic aperture; 6.1.4. The vowel space: cardinal vowels 327 $a6.1.5. The temporal dimension 330 $aCommunicating by speech is seemingly one of the most natural activities for humans. However, despite its apparent obviousness and ease, speech production is a very complex activity with multiple levels of organization involved with transforming cognitive intent into a meaningful sequence of sounds. This book establishes a connection between the physiology of speech and linguistics, and provides a detailed account of speech production processes, indicating how various languages of the world make use of human anthropophonic capacities. The book also offers new insights into the possible ways in 410 0$aISTE 606 $aSpeech 606 $aPhonetics 615 0$aSpeech. 615 0$aPhonetics. 676 $a414.8 676 $a612.7/8 700 $aMarchal$b Alain$0287549 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830172003321 996 $aFrom speech physiology to linguistic phonetics$94044425 997 $aUNINA