LEADER 03599nam 2200601 a 450 001 9910830165703321 005 20201005164219.0 010 $a1-280-27456-5 010 $a9786610274567 010 $a0-470-01150-5 010 $a0-470-01149-1 035 $a(CKB)1000000000356166 035 $a(EBL)232666 035 $a(SSID)ssj0000201588 035 $a(PQKBManifestationID)11216662 035 $a(PQKBTitleCode)TC0000201588 035 $a(PQKBWorkID)10245409 035 $a(PQKB)10329381 035 $a(MiAaPQ)EBC232666 035 $a(OCoLC)85820806 035 $a(EXLCZ)991000000000356166 100 $a20040602d2005 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aMetabolomics by in vivo NMR$b[electronic resource] /$feditors, R.G. Shulman and D.L. Rothman 210 $aChichester, West Sussex ;$aHoboken, NJ $cJohn Wiley & Sons$dc2005 215 $a1 online resource (209 p.) 300 $aDescription based upon print version of record. 311 1 $a0-470-84719-0 320 $aIncludes bibliographical references and index. 327 $aIn vivo NMR spectroscopy-techniques; direct detection; MRS; kinetics & labels; fluxes; concentrations / R. deGraaf -- MCA for the NMR spectroscopists / D. Fell and D.L. Rothman -- MRS studies of the role of muscle glycogen synthesis pathway in the pathophysiology of type 2 diabetes / D.L. Rothman, J.R.A. Schafer, & R.G. Shulman -- Phosphorylation of allosteric enzymes can serve homeostasis rather than control flux: the example of glycogen synthase / James R.A. Schafer ... [et al.] -- Regulation of glycogen metabolism in muscle during exercise / T. Price, D.L. Rothman and R.G. Shulman -- 13C NMR studies of myocardial glycogen metabolism / M. Laughlin, D.L. Rothman and R.G. Shulman -- Bioenergetics implication of metabolic fluctuation during muscle contraction / Thomas Jue -- Lactate, glycogen and fatigue / R.G. Shulman and D.L. Rothman -- Futile cycling in yeast: how to control gluttony in the midst of plenty / Jan den Hollander and Robert G. Shulman -- Trehalose energetics in yeast spores / Robert G. Shulman and Jan den Hollander -- Metabolic networks in the liver by 2H and 13C NMR / A. Dean Sherry and Craig R. Malloy -- Summarized reflections on metabolism / R.G. Shulman and James R.A. Schafer. 330 $aMetabolism By In Vivo NMR reviews and extends the experimental and theoretical reports concerning in vivo NMR, a pioneering approach that offers versatile new ways of studying metabolic pathways. Perfectly timed to coincide with recent findings that demonstrate the novelty and strength of this approach, the book covers recent applications in biochemistry, medicine, and psychology; in vivo NMR techniques; MCA; glucose metabolism focusing on glycogen; the value of muscle glycogen measurements in exercise; and much more.This book is unique in linking in vivo 13C NMR meas 606 $aMetabolism 606 $aMetabolism$xResearch$xMethodology 606 $aNuclear magnetic resonance spectroscopy 615 0$aMetabolism. 615 0$aMetabolism$xResearch$xMethodology. 615 0$aNuclear magnetic resonance spectroscopy. 676 $a572.4 676 $a572.41072 676 $a572/.41/072 701 $aShulman$b R. G$g(Robert Gerson)$01611280 701 $aRothman$b D. L$g(Douglas L.)$01611281 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830165703321 996 $aMetabolomics by in vivo NMR$93939460 997 $aUNINA