LEADER 02347nam 2200625 450 001 9910460531403321 005 20200520144314.0 010 $a1-940325-31-5 010 $a1-940325-04-8 035 $a(CKB)3710000000448678 035 $a(EBL)4357416 035 $a(SSID)ssj0001534307 035 $a(PQKBManifestationID)12590107 035 $a(PQKBTitleCode)TC0001534307 035 $a(PQKBWorkID)11494904 035 $a(PQKB)10030335 035 $a(MiAaPQ)EBC4357416 035 $a(Au-PeEL)EBL4357416 035 $a(CaPaEBR)ebr11151618 035 $a(OCoLC)937404249 035 $a(EXLCZ)993710000000448678 100 $a20160612h20142014 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aCare coordination and transition management $ecore curriculum /$feditors, Sheila A. Haas, Beth Ann Swan, Traci S. Haynes 205 $aFirst edition. 210 1$aPitman, New Jersey :$cAmerican Academy of Ambulatory Care Nursing,$d2014. 210 4$dİ2014 215 $a1 online resource (232 p.) 300 $aDescription based upon print version of record. 311 $a1-940325-02-1 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aPages:1 to 25; Pages:26 to 50; Pages:51 to 75; Pages:76 to 100; Pages:101 to 125; Pages:126 to 150; Pages:151 to 175; Pages:176 to 200; Pages:201 to 225; Pages:226 to 232 330 $aEvidence-based registered nurse (RN) competencies to provide education for and demonstrate the effectiveness of the role of the RN in care coordination and transition management (CCTM). 606 $aNursing care plans$vOutlines, syllabi, etc 606 $aHospitals$xCase management services$vOutlines, syllabi, etc 606 $aHospitals$xCase management services 608 $aElectronic books. 615 0$aNursing care plans 615 0$aHospitals$xCase management services 615 0$aHospitals$xCase management services. 676 $a362.173068 702 $aHaas$b Sheila A. 702 $aSwan$b Beth Ann 702 $aHaynes$b Traci S. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910460531403321 996 $aCare coordination and transition management$92024495 997 $aUNINA LEADER 05219nam 22006014a 450 001 9910830158703321 005 20230617021318.0 010 $a1-280-52042-6 010 $a9786610520428 010 $a3-527-60533-9 010 $a3-527-60149-X 035 $a(CKB)1000000000019325 035 $a(EBL)481584 035 $a(SSID)ssj0000102874 035 $a(PQKBManifestationID)11622515 035 $a(PQKBTitleCode)TC0000102874 035 $a(PQKBWorkID)10060381 035 $a(PQKB)10009578 035 $a(MiAaPQ)EBC481584 035 $a(OCoLC)55688272 035 $a(EXLCZ)991000000000019325 100 $a20030612d2003 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aAnalysing gene expression$b[electronic resource] $ea handbook of methods: possibilities and pitfalls /$fedited by Stefan Lorkowski and Paul Cullen 210 $aWeinheim ;$aNew York $cWiley-VCH$dc2003 215 $a1 online resource (984 p.) 300 $aDescription based upon print version of record. 311 $a3-527-30488-6 320 $aIncludes bibliographical references and index. 327 $aAnalysing Gene Expression A Handbook of Methods Possibilities and Pitfalls; Foreword; Preface; Contents; List of Contributors; Volume 1; 1 Basic concepts of gene expression; 1.1 Introduction; 1.2 Basics of transcription and translation in the cell; 1.2.1 Introduction; 1.2.2 Transcription; 1.2.3 Translation; 1.2.4 Summary; 1.3 Regulation of transcription; 1.3.1 Introduction; 1.3.2 mRNA expression profiles - the transcriptome; 1.3.3 Protein expression profiles - the proteome; 1.3.4 Interaction between genes and proteins - the interactome; 1.3.5 The transcription machinery and core promoters 327 $a1.3.6 Regulatory promoters1.3.7 Enhancers; 1.3.8 Locus control regions; 1.3.9 Matrix attachment regions; 1.3.10 Insulators; 1.3.11 RIDGEs - Regions of increased gene expression; 1.3.12 Enhanceosomes; 1.3.13 Chromatin; 1.3.14 Silencer elements; 1.3.15 Transcription factors, repressors and co-repressors; 1.3.16 Epigenetics; 1.3.17 Summary and conclusions; 1.4 Post-transcriptional regulation; 1.4.1 Introduction; 1.4.2 Regulation of RNA stability and degradation; 1.4.3 Regulation of transcription elongation; 1.4.3.1 Introduction; 1.4.3.2 Regulation of transcription elongation in prokaryotes 327 $a1.4.3.3 Regulation of transcription elongation in eukaryotes1.4.3.4 Conclusions; 1.4.4 Differential/alternative pre-mRNA splicing; 1.4.5 Trans-RNA splicing; 1.4.6 Regulation of mRNA transport; 1.4.7 Directed intracellular mRNA localisation; 1.4.8 Regulation of mRNA polyadenylation; 1.4.9 Antisense RNA; 1.4.10 RNA editing; 1.4.11 Summary and conclusions; 1.5 Post-translational modification of proteins; 1.5.1 Introduction; 1.5.2 Proteolytic cleavage of proteins; 1.5.3 Acylation; 1.5.4 Prenylation; 1.5.5 Methylation; 1.5.6 Sulphation; 1.5.7 Phosphorylation; 1.5.8 Ubiquitination 327 $a1.5.9 Glycosylation1.5.10 Conclusions; 1.6 Correlation of mRNA and protein expression; 1.6.1 Introduction; 1.6.2 Levels of mRNA and protein expression: correlations and discrepancies; 1.6.3 Conclusions; 1.7 Housekeeping genes, internal and external standards; 1.7.1 What are housekeeping genes?; 1.7.2 Survey of the most important housekeeping genes; 1.7.2.1 Glyceraldehyde-3-phosphate dehydrogenase; 1.7.2.2 ?-Actin; 1.7.3 Other commonly used housekeeping genes; 1.7.3.1 Ribosomal RNA (rRNA); 1.7.4 New identified 'maintenance genes'; 1.7.5 Methods of quantification 327 $a1.7.5.1 Normalisation (via internal standards)1.7.5.2 Standard curves (via external standards); 1.7.5.3 Alternative methods (via internal standards); 1.7.6 Summary; 1.8 Classification of differential gene expression technologies; 1.8.1 Introduction; 1.8.2 From single genes to transcriptomes; 1.8.3 Methods of classification; 1.8.4 Conclusions; 1.9 Summary; 1.10 References; 2 Sample preparation and supplementary tools; 2.1 Introduction; 2.2 Preparation of cells and tissues; 2.2.1 Immunopurification of cells; 2.2.2 Differential-velocity centrifugation/countercurrent elutriation 327 $a2.2.3 Surface affinity chromatography 330 $aThis book combines the experience of 225 experts on 900 pages. Scientists worldwide are currently overwhelmed by the ever-increasing number and diversity of genome projects. This handbook is your guide through the jungle of new methods and techniques available to analyse gene expression - the first to provide such a broad view of the measurement of mRNA and protein expression in vitro, in situ and even in vivo. Despite this broad approach, detail is sufficient for you to grasp the principles behind each method. In each case, the authors weigh up the advantages and disadvantages, paying parti 606 $aGene expression 615 0$aGene expression. 676 $a572.8/65 676 $a572.865 701 $aLorkowski$b Stefan$0149121 701 $aCullen$b Paul$cDr.$0308473 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830158703321 996 $aAnalysing gene expression$93939410 997 $aUNINA