LEADER 02917oam 2200649zu 450 001 9910830150003321 005 20210721054331.0 010 $a1-280-55847-4 010 $a9786610558476 010 $a3-527-60080-9 035 $a(CKB)1000000000019402 035 $a(SSID)ssj0000309544 035 $a(PQKBManifestationID)11207103 035 $a(PQKBTitleCode)TC0000309544 035 $a(PQKBWorkID)10267754 035 $a(PQKB)11220338 035 $a(MiAaPQ)EBC4957977 035 $a(Au-PeEL)EBL4957977 035 $a(CaONFJC)MIL55847 035 $a(OCoLC)85820117 035 $a(PPN)243015658 035 $a(EXLCZ)991000000000019402 100 $a20160829d2002 uy 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aSingle molecule detection in solution : methods and applications 210 31$a[Place of publication not identified]$cWiley VCH$d2002 215 $a1 online resource (377 pages) 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a3-527-40310-8 330 $aThe detection of single molecules opens up new horizons in analytical chemistry, biology and medicine. This discipline, which belongs to the expanding field of nanoscience, has been rapidly emerging over the last ten years. This handbook provides a thorough overview of the field. It begins with basics of single molecule detection in solution, describes methods and devices (fluorescense correlation spectroscopy, surface enhanced Raman scattering, sensors, especially dyes, screening techniques, especially confocal laser scanning microscopy). In the second part, various applications in life sciences and medicine provide the latest research results. This modern handbook is a highly accessible reference for a broad community from advanced researchers, specialists and company professionals in physics, spectroscopy, biotechnology, analytical chemistry, and medicine. Written by leading authorities in the field, it is timely and fills a gap - up to now there exists no handbook concerning this theme. 606 $aFluorescence spectroscopy 606 $aRaman spectroscopy 606 $aMolecules 606 $aSolution (Chemistry) 606 $aAnalytical Chemistry$2HILCC 606 $aChemistry$2HILCC 606 $aPhysical Sciences & Mathematics$2HILCC 615 0$aFluorescence spectroscopy 615 0$aRaman spectroscopy 615 0$aMolecules 615 0$aSolution (Chemistry) 615 7$aAnalytical Chemistry 615 7$aChemistry 615 7$aPhysical Sciences & Mathematics 676 $a543/.56 702 $aEnderlein$b J 702 $aKeller$b Richard A 702 $aZander$b Ch 801 0$bPQKB 906 $aBOOK 912 $a9910830150003321 996 $aSingle molecule detection in solution : methods and applications$94079457 997 $aUNINA