LEADER 02788nam 22006254a 450 001 9910830149303321 005 20221206154011.0 010 $a1-280-41147-3 010 $a9786610411474 010 $a0-470-36282-0 010 $a0-471-78954-2 010 $a0-471-78953-4 035 $a(CKB)1000000000354587 035 $a(EBL)257072 035 $a(OCoLC)71295472 035 $a(SSID)ssj0000132646 035 $a(PQKBManifestationID)11129734 035 $a(PQKBTitleCode)TC0000132646 035 $a(PQKBWorkID)10040317 035 $a(PQKB)10799442 035 $a(MiAaPQ)EBC257072 035 $a(EXLCZ)991000000000354587 100 $a20050914d2006 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aCritical infrastructure protection in homeland security$b[electronic resource] $edefending a networked nation /$fTed G. Lewis 210 $aHoboken, N.J. $cWiley-Interscience$dc2006 215 $a1 online resource (488 p.) 300 $a"Published simultaneously in Canada"--T.p. verso. 311 $a0-471-78628-4 320 $aIncludes bibliographical references and index. 327 $aStrategy -- Origins -- Challenges -- Networks -- Vulnerability analysis -- Risk analysis -- Water -- SCADA -- Power -- Energy -- Telecommunications -- Internet -- Cyber-threats -- Cyber-security. 330 $aA scientific approach to the new field of critical infrastructure protectionThis book offers a unique scientific approach to the new field of critical infrastructure protection: it uses network theory, optimization theory, and simulation software to analyze and understand how infrastructure sectors evolve, where they are vulnerable, and how they can best be protected. The author demonstrates that infrastructure sectors as diverse as water, power, energy, telecommunications, and the Internet have remarkably similar structures. This observation leads to a rigorous approach to vulnera 606 $aComputer networks$xSecurity measures$zUnited States 606 $aComputer security$zUnited States$xPlanning 606 $aTerrorism$zUnited States$xPrevention 606 $aTerrorism$xGovernment policy$zUnited States 606 $aCivil defense$zUnited States 615 0$aComputer networks$xSecurity measures 615 0$aComputer security$xPlanning. 615 0$aTerrorism$xPrevention. 615 0$aTerrorism$xGovernment policy 615 0$aCivil defense 676 $a005.8 700 $aLewis$b T. G$g(Theodore Gyle),$f1941-$0857489 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830149303321 996 $aCritical infrastructure protection in homeland security$94079451 997 $aUNINA LEADER 04404nam 22005295 450 001 9910254528903321 005 20200630231945.0 010 $a3-319-30590-5 024 7 $a10.1007/978-3-319-30590-5 035 $a(CKB)3710000000829590 035 $a(DE-He213)978-3-319-30590-5 035 $a(MiAaPQ)EBC4643688 035 $a(PPN)194806138 035 $a(EXLCZ)993710000000829590 100 $a20160811d2016 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aApplied Immunohistochemistry in the Evaluation of Skin Neoplasms /$fedited by Jose A. Plaza, Victor G. Prieto 205 $a1st ed. 2016. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2016. 215 $a1 online resource (IX, 385 p. 264 illus., 159 illus. in color.) 311 $a3-319-30588-3 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aImmunohistology and Molecular Studies of Epithelial Tumors -- Immunohistology and Molecular Studies of Sweat Gland Tumors -- Immunohistology and Molecular Studies of Follicular Tumors -- Use of Immunohistochemical and Molecular Studies in the Evaluation of the Sebaceous Neoplasms -- Cutaneous Metastasis -- Immunohistology and Molecular Studies of Fibrohistiocytic and Myofibroblastic Cutaneous Tumors -- Immunohistology and Molecular Studies of Smooth Muscle and Neural Cutaneous Tumors -- New Insights in Vascular Lesions Development and Identification with Immunohistochemical Markers -- Immunohistology and Molecular Studies of Cutaneous B-cell Lymphomas -- Immunohistology and Molecular Studies of Cutaneous T-cell Lymphomas and Mimics -- Immunohistology of Leukemia Cutis and Histiocytic Tumors -- Immunohistology of Melanocytic Lesions -- Molecular Studies of Melanocytic Lesions -- Sentinel Lymph Node in Melanoma. 330 $aThis book provides a comprehensive, state-of-the-art account of the role of immunohistochemistry in the diagnosis of skin tumors, which is crucial given that overlapping histologic features and unusual morphologic changes can lead to considerable diagnostic uncertainty. The book reviews in detail the sensitivity and specificity of commonly available antibodies and their pattern of immunostaining. Readers will learn when to order antibodies and how to interpret findings. In addition, prognostic markers are evaluated and emphasis placed on the pitfalls commonly encountered when evaluating these neoplasms. The informative text is complemented by a wealth of superb images. Helpful histograms and algorithms are included, and clear guidance is provided on the application and interpretation of less commonly used antibodies and immunostains. With the emergence of many immunomarkers, immunohistochemistry has become a vital ancillary diagnostic tool in dermatopathology and an essential adjunct for the correct identification of skin neoplasms. Indeed, immunohistochemistry has replaced simple morphologic evaluation as the definitive diagnostic method for various tumor types. The complexity of some skin neoplasms makes it imperative that the role of immunohistochemistry in subtyping these conditions is clearly understood. Against this background, Applied Immunohistochemistry in the Evaluation of Skin Neoplasms will serve as an extremely valuable resource for practicing dermatopathologists and pathologists. 606 $aPathology 606 $aDermatology 606 $aDiagnosis, Laboratory 606 $aPathology$3https://scigraph.springernature.com/ontologies/product-market-codes/H4800X 606 $aDermatology$3https://scigraph.springernature.com/ontologies/product-market-codes/H1900X 606 $aLaboratory Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/B15007 615 0$aPathology. 615 0$aDermatology. 615 0$aDiagnosis, Laboratory. 615 14$aPathology. 615 24$aDermatology. 615 24$aLaboratory Medicine. 676 $a616.07 702 $aPlaza$b Jose A$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aPrieto$b Victor G$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910254528903321 996 $aApplied Immunohistochemistry in the Evaluation of Skin Neoplasms$92523143 997 $aUNINA