LEADER 03284nam 2200649 450 001 9910452520803321 005 20200520144314.0 010 $a0-520-95651-6 024 7 $a10.1525/9780520956513 035 $a(CKB)2550000001123646 035 $a(EBL)1429398 035 $a(OCoLC)862030505 035 $a(SSID)ssj0001190078 035 $a(PQKBManifestationID)11813157 035 $a(PQKBTitleCode)TC0001190078 035 $a(PQKBWorkID)11189310 035 $a(PQKB)10192375 035 $a(MiAaPQ)EBC1429398 035 $a(DE-B1597)519579 035 $a(OCoLC)932458726 035 $a(DE-B1597)9780520956513 035 $a(Au-PeEL)EBL1429398 035 $a(CaPaEBR)ebr10773730 035 $a(CaONFJC)MIL525363 035 $a(EXLCZ)992550000001123646 100 $a20131018e20132001 uy| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aAutobiography of Mark Twain$hVolume 2 /$fBenjamin Griffin and Harriet Elinor Smith, editors ; associate editors, Victor Fischer [and three others] 210 1$aBerkeley :$cUniversity of California Press,$d[2013] 210 4$dİ2001 215 $a1 online resource (773 p.) 225 1 $aMark Twain papers 300 $a"A publication of the Mark Twain Project of the Bancroft Library." 311 $a0-520-27278-1 311 $a1-299-94112-5 320 $aIncludes bibliographical references and index. 327 $tFrontmatter -- $tCONTENTS -- $tList of Dictations -- $tAcknowledgments -- $tAUTOBIOGRAPHY OF MARK TWAIN. Part 1 -- $tAUTOBIOGRAPHY OF MARK TWAIN. Part 2 -- $tExplanatory Notes -- $tAppendixes -- $tNote on the Text -- $tWord Division in This Volume -- $tReferences -- $tIndex 330 $aMark Twain's complete, uncensored Autobiography was an instant bestseller when the first volume was published in 2010, on the centennial of the author's death, as he requested. Published to rave reviews, the Autobiography was hailed as the capstone of Twain's career. It captures his authentic and unsuppressed voice, speaking clearly from the grave and brimming with humor, ideas, and opinions. The eagerly-awaited Volume 2 delves deeper into Mark Twain's life, uncovering the many roles he played in his private and public worlds. Filled with his characteristic blend of humor and ire, the narrative ranges effortlessly across the contemporary scene. He shares his views on writing and speaking, his preoccupation with money, and his contempt for the politics and politicians of his day. Affectionate and scathing by turns, his intractable curiosity and candor are everywhere on view. Editors: Benjamin Griffin and Harriet E. Smith Associate Editors: Victor Fischer, Michael B. Frank, Sharon K. Goetz and Leslie Diane Myrick   410 0$aMark Twain Papers 606 $aAuthors, American$y19th century$vBiography 608 $aElectronic books. 615 0$aAuthors, American 676 $a773 701 $aGriffen$b Benjamin$01044180 701 $aSmith$b Harriet Elinor$01030003 701 $aFischer$b Victor$0858971 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910452520803321 996 $aAutobiography of Mark Twain$92469660 997 $aUNINA LEADER 05217nam 22006374a 450 001 9910830101603321 005 20230828225241.0 010 $a1-280-74810-9 010 $a9786610748105 010 $a0-470-76079-6 010 $a0-470-77501-7 010 $a1-4051-7287-8 035 $a(CKB)1000000000341937 035 $a(EBL)284174 035 $a(OCoLC)437176080 035 $a(SSID)ssj0000213063 035 $a(PQKBManifestationID)11184859 035 $a(PQKBTitleCode)TC0000213063 035 $a(PQKBWorkID)10150634 035 $a(PQKB)11125437 035 $a(MiAaPQ)EBC284174 035 $a(EXLCZ)991000000000341937 100 $a20051206d2006 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aNutrition and arthritis$b[electronic resource] /$fMargaret Rayman, Alison Callaghan 210 $aOxford ;$aAmes, Iowa $cBlackwell Pub.$d2006 215 $a1 online resource (282 p.) 300 $aDescription based upon print version of record. 311 $a1-4051-2418-0 320 $aIncludes bibliographical references and index. 327 $aContents; 8.6.2 Iron status in OA and RA patients; Acknowledgements; Abbreviations; 1 Introduction; 1.1 The range of rheumatic diseases; 1.2 Rheumatoid arthritis (RA):description; 1.3 Osteoarthritis (OA):description; 1.4 Incidence and prevalence; 1.5 Mortality; 1.6 Morbidity; 1.7 Economic cost of arthritis; 1.8 The aim of this book; 2 Classification,pathology and measures of disease assessment; 2.1 Classification of OA; 2.2 Classification of RA; 2.3 Pathology of OA; 2.3.1 General features of OA; 2.3.2 Structure of cartilage; 2.3.3 Pathogenesis of OA; 2.3.3.1 Cartilage degradation 327 $a2.3.3.2 Nitric oxide synthesis damages chondrocytes2.3.3.3 Sulphation pattern of GAGs in articular cartilage; 2.3.3.4 Bone changes; 2.3.3.5 Inflammation; 2.3.3.6 Angiogenesis; 2.3.3.7 Oxidative stress; 2.4 Pathology of RA; 2.4.1 General features of RA; 2.4.2 Immunopathogenesis and production of inflammatory mediators; 2.4.3 Autoantibodies:rheumatoid factor; 2.4.4 Glycosylation patterns of immunoglobulins and complement activation; 2.4.5 Dietary lectins,gut translocation and the shared epitope; 2.4.6 Abnormal gut microflora 327 $a2.4.7 Reactive oxygen and nitrogen species involved in damage to the rheumatoid joint2.4.7.1 Phagocytosis; 2.4.7.2 Hypoxia reperfusion injury and joint pH; 2.4.7.3 Involvement of nitric oxide and peroxynitrite; 2.4.7.4 Consequences of the production of reactive oxygen and nitrogen species in the RA joint; 2.4.8 Lipid abnormalities and cardiovascular risk in RA; 2.4.8.1 C-Reactive Protein (CRP); 2.4.8.2 Dyslipidaemia; 2.4.8.3 Endothelial dysfunction; 2.4.8.4 Oxidised LDL in the joint and the formation of fatty streaks; 2.4.8.5 Adhesion molecules; 2.4.8.6 Haemostatic changes 327 $a2.4.8.7 Elevated homocysteine and low vitamin B6 status2.4.8.8 Elevated homocysteine and impaired sulphur metabolism; 2.4.8.9 Insulin resistance; 2.4.9 Angiogenesis; 2.4.10 Osteoporosis; 2.5 Assessment of severity of RA and OA; 2.5.1 Outcome measures for RA; 2.5.1.1 Patient 's global assessment; 2.5.1.2 Pain; 2.5.1.3 Disability; 2.5.1.4 Swollen and tender joint counts; 2.5.1.5 Acute phase reactants; 2.5.1.6 RA quality of life index; 2.5.1.7 Radiological assessment; 2.5.2 Some outcome measures for OA; 2.5.2.1 Patient global assessment; 2.5.2.2 Pain score; 2.5.2.3 New joint score 327 $a2.5.2.4 Severity score2.5.2.5 Disability; 2.5.2.6 Radiological assessment; 3 Aetiology and risk factors for osteoarthritis and rheumatoid arthritis; 3.1 Introduction; 3.2 Genetic risk factors; 3.3 Age; 3.4 Gender; 3.5 Biomechanical factors as risk factors for OA; 3.5.1 Occupation,sport and physical activity; 3.5.2 Joint trauma and surgery; 3.5.3 Load distribution and malalignment; 3.5.4 Muscle weakness; 3.6 Obesity; 3.7 Smoking; 3.8 Dietary factors; 3.8.1 Olive oil; 3.8.2 Fish and n-3 polyunsaturated fatty acid (PUFA); 3.8.3 Meat; 3.8.4 Fruit and vegetables; 3.8.5 Antioxidants 327 $a3.8.6 Vitamin C 330 $aArthritis affects millions of people throughout the world and while its treatment is usually medical or surgical, there exists an increasingly large body of evidence concerning the positive effects of nutrition on the condition. There are over two hundred forms of rheumatoid disease, with conditions varying in prevalence. In this important title the authors have focussed on osteoarthritis (OA) and rheumatoid arthritis (RA), the most common arthritic diseases with the largest body of dietary data. Including coverage of disease incidence and prevalence, pathology, aetiology and meas 606 $aArthritis$xNutritional aspects 606 $aArthritis$xDiet therapy 615 0$aArthritis$xNutritional aspects. 615 0$aArthritis$xDiet therapy. 676 $a616.7/220654 676 $a616.7220654 700 $aRayman$b Margaret$0965284 701 $aCallaghan$b Alison$0965285 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830101603321 996 $aNutrition and arthritis$92190168 997 $aUNINA