LEADER 05279nam 2200625Ia 450 001 9910830080403321 005 20230721005135.0 010 $a1-282-12366-1 010 $a9786612123665 010 $a0-470-74546-0 010 $a0-470-74545-2 035 $a(CKB)1000000000719711 035 $a(EBL)427958 035 $a(SSID)ssj0000354420 035 $a(PQKBManifestationID)11273861 035 $a(PQKBTitleCode)TC0000354420 035 $a(PQKBWorkID)10322574 035 $a(PQKB)11567099 035 $a(MiAaPQ)EBC427958 035 $a(OCoLC)352789951 035 $a(EXLCZ)991000000000719711 100 $a20090116d2009 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 10$aManagement of acute coronary syndromes$b[electronic resource] /$fEli V. Gelfand and Christopher P. Cannon 210 $aChichester, West Sussex ;$aHoboken, NJ $cJohn Wiley & Sons$d2009 215 $a1 online resource (242 p.) 300 $aDescription based upon print version of record. 311 $a0-470-72557-5 320 $aIncludes bibliographical references and index. 327 $aManagement of Acute Coronary Syndromes; Contents; List of contributors; Foreword; Chapter 1 Pathophysiology of acute coronary syndromes; Introduction; Formation of atherosclerotic plaque; Plaque instability and the development of ACS; Myocardial ischemia; Thrombus formation; Platelets; Secondary hemostasis; Dynamic obstruction; Progressive mechanical obstruction; Inflammation; Secondary unstable angina; References; Chapter 2 Diagnosis of acute coronary syndrome; Introduction; Definition of myocardial infarction; History; Risk factors; Physical examination; Electrocardiography 327 $aThe pathophysiologic basis of ST segment changes during ischemiaElectrocardiography in ST-elevation MI and identification of the infarct-related artery; Electrocardiography in unstable angina and NSTEMI; Cardiac biomarkers; Noninvasive imaging; Echocardiography; Myocardial perfusion imaging; Coronary computed tomography; Cardiovascular magnetic resonance imaging; Stress testing for diagnosis of ACS; Overall diagnostic pathway for ACS; References; Chapter 3 Unstable angina and non-ST-elevation myocardial infarction; Introduction; Causes of UA/NSTEMI; Presentation of UA/NSTEMI 327 $aGeneral strategies in management of UA/NSTEMIRisk stratification of patients with UA/NSTEMI; Initial management of UA/NSTEMI in the emergency department; Pharmacologic treatment of ischemia in UA/NSTEMI; Beta-blockers; Nitrates; Calcium channel blockers; Angiotensin-converting enzyme inhibitors; Morphine; Oxygen; Invasive versus conservative strategy; Antiplatelet therapy in UA/NSTEMI; Aspirin; Clopidogrel; Prasugrel; Glycoprotein IIb/IIIa inhibitors; Anticoagulant therapy in UA/NSTEMI; Unfractionated heparin; Enoxaparin; Direct thrombin inhibitors; Fondaparinux 327 $aOral anticoagulation in UA/NSTEMIFibrinolysis in UA/NSTEMI; Early lipid-lowering therapy in patients with UA/NSTEMI; Predischarge noninvasive risk stratification after UA/NSTEMI; Overall management of UA/NSTEMI; References; Chapter 4 ST-segment-elevation myocardial infarction; Introduction; Global treatment goals in STEMI; Prehospital management and triage; Transport decisions; Management prior to reperfusion; Primary reperfusion therapy for STEMI; Fibrinolysis; Combination fibrinolysis; Markers of fibrinolysis effectiveness; Complications of fibrinolysis 327 $aPrimary percutaneous coronary interventionComparison of PCI with fibrinolysis; Timing of primary PCI; PCI following fibrinolytic therapy; Rescue PCI; Facilitated PCI; Routine PCI after successful fibrinolysis; Overall reperfusion strategy; Coronary artery bypass grafting for treatment of STEMI; Adjunctive pharmacologic treatment of STEMI; Antiplatelet agents; Anticoagulation therapy; Other adjunctive therapy; Hospital care following successful reperfusion; References; Chapter 5 Special considerations in acute coronary syndromes; Secondary unstable angina 327 $aAcute coronary syndrome in patients with diabetes mellitus 330 $aAcute Coronary Syndrome covers the spectrum of clinical conditions ranging from unstable angina to non-ST elevation myocardial infarction and ST elevation myocardial infarction. These life-threatening disorders are a major cause of emergency medical care, hospitalization and mortality. Management of Acute Coronary Syndromes is designed to provide busy clinicians with a comprehensive guide to the investigation, diagnosis and treatment of these syndromes. It encompasses the latest technologies, including the use of biomarkers and non-invasive imaging procedures. For each condition, t 606 $aCoronary heart disease 606 $aMyocardial infarction 615 0$aCoronary heart disease. 615 0$aMyocardial infarction. 676 $a616.123 676 $a616.12306 700 $aGelfand$b Eli V$01672752 701 $aCannon$b Christopher P$0893564 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830080403321 996 $aManagement of acute coronary syndromes$94036305 997 $aUNINA