LEADER 03750oam 2200625zu 450 001 9910830064503321 005 20230607214043.0 010 $a9786610556106 010 $a0-470-86869-4 010 $a1-280-55610-2 035 $a(CKB)111087027104884 035 $a(SSID)ssj0000100257 035 $a(PQKBManifestationID)11131563 035 $a(PQKBTitleCode)TC0000100257 035 $a(PQKBWorkID)10020948 035 $a(PQKB)11185319 035 $a(MiAaPQ)EBC4957431 035 $a(Au-PeEL)EBL4957431 035 $a(CaONFJC)MIL55610 035 $a(OCoLC)85819857 035 $a(EXLCZ)99111087027104884 100 $a20160829d2001 uy 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt 182 $cc 183 $acr 200 00$aAgeing vulnerability : causes and interventions 210 31$a[Place of publication not identified]$cWiley$d2001 215 $a1 online resource (291 pages) 225 1 $aNovartis Foundation Symposia ;$vv.204 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a0-471-49438-0 311 $a0-470-86868-6 330 $aAgeing at individual and population levels presents one of the greatest challenges to humankind as we enter this new century. Throughout the world today older adults are the fastest growing population groups. Mortality rates have declined in virtually all countries, raising the average life expectancy in the developing countries to the high 60s, and the high 70s in the developed world. Ageing is associated with an increased risk for development of chronic diseases that contribute to morbidity and mortality. It is estimated that by 2020 over two-thirds of deaths in the developing world will be caused by non-communicable diseases. This fact, along with the high levels of chronic morbidity associated with ageing in developed countries, represents a potentially overwhelming stress to health and social care systems globally. The frontiers of knowledge in relation to human ageing have been pushed back in recent years and it is to be expected that continuous progress will be made towards understanding the basic ageing processes.; Further research is now urgently needed to improve our understanding of the relationship between ageing and the pathogenesis of age-related diseases in order to identify more effective means of prevention, amelioration and management of such diseases, and reduce the social and economic impacts of population ageing and the related burden of age-associated morbidity. Age-related morbidity and mortality differ dramatically in different individuals. The focus of this book is on individual differences in susceptibility to age-related disorders. Specific chapters in the book deal with age-related pathology in the brain, age-related processes in stem cells, and age-related effects on the immune system and in bone, muscle and cardiovascular tissue. Bringing together the leading researchers in the ageing field to discuss their work, 330 8 $athis book is compulsory reading for all those interested in the biology of ageing. 410 0$aNovartis Foundation Symposia 606 $aAging 606 $aGrowth and Development 606 $aPhysiological Processes 606 $aPhysiological Phenomena 606 $aPhenomena and Processes 615 2$aAging 615 2$aGrowth and Development 615 2$aPhysiological Processes 615 2$aPhysiological Phenomena 615 2$aPhenomena and Processes 676 $a612.67 702 $aBock$b Gregory 702 $aGoode$b Jamie 801 0$bPQKB 906 $aBOOK 912 $a9910830064503321 996 $aAgeing vulnerability : causes and interventions$94117012 997 $aUNINA