LEADER 05323nam 2200625Ia 450 001 9910830017103321 005 20230721025904.0 010 $a1-280-93510-3 010 $a9786610935109 010 $a0-470-11420-7 010 $a0-470-11419-3 035 $a(CKB)1000000000355502 035 $a(EBL)312187 035 $a(OCoLC)173621245 035 $a(SSID)ssj0000146714 035 $a(PQKBManifestationID)11137545 035 $a(PQKBTitleCode)TC0000146714 035 $a(PQKBWorkID)10186608 035 $a(PQKB)10456289 035 $a(MiAaPQ)EBC312187 035 $a(EXLCZ)991000000000355502 100 $a20060815d2007 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aEncyclopedia of infectious diseases$b[electronic resource] $emodern methodologies /$fedited by Michel Tibayrenc 210 $aHoboken, N.J. $cWiley-Liss$dc2007 215 $a1 online resource (807 p.) 300 $aDescription based upon print version of record. 311 $a0-471-65732-8 320 $aIncludes bibliographical references and index. 327 $aENCYCLOPEDIA OF INFECTIOUS DISEASES; Contents; Contributors; Biographical; Introduction: Infectious Diseases, the Major Challenge of Twenty-First Century Medicine; 1. Pulmonary Tuberculosis and Mycobacterium Tuberculosis: Modern Molecular Epidemiology and Perspectives; 1.1. Introduction; 1.2. General Points on Mycobacterium Tuberculosis (MTB) and Pulmonary Tuberculosis (PTB); 1.2.1. Classification and Cellular Characteristics; 1.2.2. Transmission and Multiplication of MTB; 1.2.3. Clinical and Subclinical TB; 1.2.4. Diagnosis of MTB Species; 1.2.5. Treatment, Drug Resistance, and Control 327 $a1.3. Genetics of MTB, Molecular Tools, and Population Structure1.3.1. Genome and Genetic Diversity of MTB; 1.3.2. Genetic Tools for Molecular Epidemiology; 1.3.3. How Should the Most Appropriate Molecular Marker be Chosen?; 1.3.4. Population Structure of MTB and Epidemiological Consequences; 1.4. Use of Molecular Epidemiology for Understanding Tuberculosis Transmission and Pathogenesis; 1.4.1. MTB Families and Worldwide Distribution; 1.4.2. MTB in Developing Versus Developed Countries; 1.4.3. Clinical and Epidemiological Relevance of Molecular Epidemiology at the Local Level 327 $a1.4.4. Use of Genotyping to Study the Impact of HIV/AIDS and Drug Resistance on Pathogenesis and Transmission1.5. Urgent Needs for TB Control, Limitations, and New Issues for Molecular Epidemiology; 1.5.1. Urgent Needs for TB Control and Molecular Epidemiology; 1.5.2. Limitations of Modern Molecular Tools; 1.5.3. Promising New Technologies; 1.6. Conclusion and Perspectives; Acknowledgments; Abbreviations; Glossary; References; 2. Diseases that Threaten Livestock; 2.1. Introduction; 2.2. Animal Diseases Under Control; 2.2.1. General Considerations; 2.2.2 Description of the Diseases 327 $a2.3. Diseases that Are an Economic Burden and Hamper International Trade in Animals and Animal Products2.3.1. General Considerations; 2.3.2. Description of the Diseases; 2.4. Animal Diseases that may Threaten Human Health; 2.4.1. Description of the Diseases; 2.5. Surveillance and Control of Transmissible Animal Diseases: Progress Expected from Modern Technologies; 2.6. Conclusion; References; 3. HIV/AIDS Infection in the World with a Special Focus on Africa; 3.1. Introduction; 3.2. Current State of the Epidemic; 3.2.1. Prevalences and Incidences in the World; 3.2.2. Mode of Transmission 327 $a3.2.3. Impact of HIV Infection on Other Endemic Diseases3.2.4. Demographic, Social, and Economic Consequences; 3.3. Molecular Epidemiology; 3.3.1. Classification of HIV; 3.3.2. Distribution of HIV-1 in Africa; 3.3.3. Implications of Recombination; 3.4. Implication of HIV Variability on Pathogenesis, Treatment, Diagnosis, and Vaccine Development in Africa; 3.4.1. Impact of HIV Variability on Diagnosis; 3.4.2. Impact of HIV Variability and Antiretroviral Therapy; 3.4.3. Impact of HIV Variability on Transmissibility and Pathogenesis; 3.4.4. Impact of HIV Variability on Vaccine Development 327 $a3.5. Access to Treatment 330 $aDiscover how the application of novel multidisciplinary, integrative approaches and technologies are dramatically changing our understanding of the pathogenesis of infectious diseases and their treatments. Each article presents the state of the science, with a strong emphasis on new and emerging medical applications. The Encyclopedia of Infectious Diseases is organized into five parts. The first part examines current threats such as AIDS, malaria, SARS, and influenza. The second part addresses the evolution of pathogens and the relationship between human genetic diversity and the spre 606 $aCommunicable diseases$vEncyclopedias 606 $aCommunicable diseases$xResearch$vEncyclopedias 615 0$aCommunicable diseases 615 0$aCommunicable diseases$xResearch 676 $a362.196/9003 676 $a362.1969003 676 $a616.903 701 $aTibayrenc$b Michel$0889901 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910830017103321 996 $aEncyclopedia of infectious diseases$94040266 997 $aUNINA