LEADER 01954nam 2200361 450 001 9910830004003321 005 20231008024938.0 010 $a1-68367-271-2 035 $a(CKB)4100000010871268 035 $a(NjHacI)994100000010871268 035 $a(EXLCZ)994100000010871268 100 $a20231008d2014 uy 0 101 0 $aeng 135 $aur||||||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aTwo-Component Signal Transduction /$fJames A. Hoch, Thomas J. Silhavy 210 1$aHoboken, New Jersey :$cJohn Wiley & Sons, Inc.,$d2014. 215 $a1 online resource (xvi, 488 pages) $cillustrations 311 $a1-119-73902-0 330 $aSignal transduction across biological membranes is crucial in enabling cells to recognize and respond to their environment. Over the past ten years, investigators working in prokaryotic molecular biology have identified a number of two-component genetic switches which mediate bacterial signal transduction for essential metabolic and developmental functions and numerous other cellular activities, including regulation of virulence factors in pathogenic bacteria. Edited and written by leading scientists, this book is the first comprehensive reference/text to cover the molecular and cellular biology of a wide variety of two-component signal transduction systems in bacteria. It will prove to be essential for microbiologists working in the areas of gene expression, pathogenesis, and bacterial metabolism, as well as for researchers studying antibiotic resistance and rational drug design. 606 $aBacterial cell walls 615 0$aBacterial cell walls. 676 $a589.90875 700 $aHoch$b James A.$01612219 702 $aSilhavy$b Thomas J. 801 0$bNjHacI 801 1$bNjHacl 906 $aBOOK 912 $a9910830004003321 996 $aTwo-Component Signal Transduction$93940897 997 $aUNINA