LEADER 03431nam 2200661 450 001 9910829987403321 005 20230421044529.0 010 $a1-282-34808-6 010 $a9786612348082 010 $a0-470-51550-3 010 $a0-470-51551-1 035 $a(CKB)1000000000377141 035 $a(EBL)470791 035 $a(OCoLC)609849844 035 $a(SSID)ssj0000295440 035 $a(PQKBManifestationID)11221173 035 $a(PQKBTitleCode)TC0000295440 035 $a(PQKBWorkID)10314652 035 $a(PQKB)10506354 035 $a(MiAaPQ)EBC470791 035 $a(EXLCZ)991000000000377141 100 $a20160816h19981998 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aEpigenetics 210 1$aChichester, [England] :$cJohn Wiley & Sons,$d1998. 210 4$dİ1998 215 $a1 online resource (320 p.) 225 1 $aNovartis Foundation Symposium ;$v214 300 $aDescription based upon print version of record. 311 $a0-471-97771-3 320 $aIncludes bibliographical references and indexes. 327 $aEPIGENETICS; Participants; Contents; Introduction; Gene silencing by methyl-CpG- binding proteins; DNAmethylation, nucleosornes and the inheritance okhromatin structure and function; General discussion I; Heritable chromatin states induced by the Polycomb and trithorax group genes; The dynamics of globin gene expression and position effects; Multiple epigenetic events regulate mating-type switching of fission yeast; General discussion I1; Nuclear organization and silencing: trafficking of Sir proteins; Epigenetic mechanisms in the regulation of the maize Suppressor-mutator transposon 327 $aTransgene-promoted epigenetic switches of chalcone synthase activity in petunia plantsGeneral discussion I11; Gene silencing in plants: relevance for genome evolution and the acquisition of genomic methylation patterns; The host defence function of genomic methylation patterns; Mammalian X chromosome inactivation; Methylation dynamics, epigenetic fidelity and X chromosome structure; General discussion IV; Imprinting and gene silencing in mice and DrosophiZa; Making sense of imprinting the mouse and human IGF2R loci; Imprinted genes in the Prader-Willi deletion; Final general discussion 327 $aSummaryIndex of contributors; Subject index 330 $aEpigenetics pertains to the development of an organism from an undifferential cell, resulting in the successive formation and development of organs and parts that did not pre-exist in the fertilized egg. An exciting and stimulating volume which used the extensive knowledge of basic transcriptional control as a foundation to explore the more complex and interesting level at which genes can be regulated. 410 0$aNovartis Foundation symposium ;$v214. 606 $aGenetic regulation$vCongresses 606 $aEpigenesis$vCongresses 606 $aDNA$xMethylation$vCongresses 615 0$aGenetic regulation 615 0$aEpigenesis 615 0$aDNA$xMethylation 676 $a572.8 676 $a572.865 701 $aChadwick$b Derek$091632 701 $aCardew$b Gail$0857118 712 12$aSymposium on Epigenetics 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910829987403321 996 $aEpigenetics$94014491 997 $aUNINA