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010   $a9786613283245
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100   $a20111111d2011      uy             0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aProtein kinases as drug targets$b[electronic resource] /$fedited by Bert Klebl, Gerhard Mu?ller, and Michael Hamacher
205   $a2nd ed.
210   $aWeinheim, Germany $cWiley-VCH$d2011
215   $a1 online resource (398 p.)
225 1 $aMethods and principles in medicinal chemistry ;$vv. 49
300   $aDescription based upon print version of record.
311   $a3-527-31790-2 
320   $aIncludes bibliographical references and index.
327   $apt. 1. Hit finding and profiling for protein kinases : assay development and screening, libraries -- pt. 2. Medicinal chemistry -- pt. 3. Application of kinase inhibitors to therapeutic indication areas.
330   $aThis timely guide to kinase inhibitor drug development is the first to cover the entire drug pipeline, from target identification to compound development and clinical application. Edited by the pioneers in the field, on the drug development side this ready reference discusses classical medicinal chemistry approaches as well as current chemical genomics strategies. On the clinical side, both current and future therapeutic application areas for kinase inhibitor drugs are addressed, with a strong focus on oncology drugs.Backed by recent clinical experience with first-generation drugs in the b
410  0$aMethods and principles in medicinal chemistry ;$vv. 49.
606   $aProtein kinases
606   $aDrugs$xDesign
615  0$aProtein kinases.
615  0$aDrugs$xDesign.
676   $a615.19
701   $aMu?ller$b Gerhard$027342
701   $aKlebl$b Bert$01635524
701   $aHamacher$b Michael$01635525
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910829935103321
996   $aProtein kinases as drug targets$93976364
997   $aUNINA