LEADER 03830nam 2200745 a 450 001 9910829903103321 005 20200520144314.0 010 $a1-282-12236-3 010 $a9786612122361 010 $a0-470-51384-5 010 $a0-470-51385-3 035 $a(CKB)1000000000376480 035 $a(EBL)470477 035 $a(SSID)ssj0000364333 035 $a(PQKBManifestationID)11262318 035 $a(PQKBTitleCode)TC0000364333 035 $a(PQKBWorkID)10394615 035 $a(PQKB)11263345 035 $a(MiAaPQ)EBC470477 035 $a(Au-PeEL)EBL470477 035 $a(CaPaEBR)ebr10297888 035 $a(CaONFJC)MIL212236 035 $a(OCoLC)181171735 035 $a(NjHacI)991000000000376480 035 $a(BIP)001228649 035 $a(EXLCZ)991000000000376480 100 $a19890710d1989 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aPhotosensitizing compounds$b[electronic resource] $etheir chemistry, biology and clinical use 210 $aChichester ;$aNew York $cWiley$d1989 210 1$aChichester :$cWiley,$d1989. 215 $a1 online resource (252 p.) 225 1 $aCiba Foundation symposium ;$v146 300 $a"A Wiley-Interscience publication." 311 $a0-471-92308-7 320 $aIncludes bibliographical references and indexes. 327 $aPHOTOSENSITIZING COMPOUNDS: THEIR CHEMISTRY, BIOLOGY AND CLINICAL USE; Contents; Introduction; What are the ideal photoproperties for a sensitizer?; The chemistry, photophysics and photosensitizing properties of phthalocyanines; General discussion : Comparison of haematoporphyrin derivative and new photosensitizers; Porphyrins as photosensitizers; Photodynamic therapy: light delivery and dosage for second-generation photosensitizers; In vivo transport and pharmacokinetic behaviour of tumour photosensitizers; Intracellular localization of photosensitizers 327 $aTissue localization of photosensitizers and the mechanism of photodynamic tissue destructionImmunosuppression in phototherapy; Effects of porphyrins on skin; Photosensitizing compounds in the treatment of psoriasis; Extracorporeal photochemotherapy in the treatment of cutaneous T cell lymphoma and autoimmune disorders affecting the skin; Photodynamic therapy of early-stage lung cancer; Long-term experience with integral photodynamic therapy of TIS bladder carcinoma; Photoradiation therapy of brain tumours; Final general discussion : Drug and light doses for photodynamic therapy 327 $aChairman's summing-upIndex of contributors; Subject index 330 $aCertain organic compounds can become toxic to biological tissue when activated by light. Many medical applications of this effect have been studied over the past twenty years, and This symposium brings together chemists, biologists, and clinicians to discuss the basic chemistry of the sensitizing compounds, their biological effects, and clinical applications in treatments of various cancers and skin disorders. 410 0$aCiba Foundation symposium ;$v146. 606 $aPhotosensitizing compounds$xTherapeutic use$xTesting$vCongresses 606 $aPhotosensitizing compounds$vCongresses 606 $aCancer$xPhotochemotherapy$vCongresses 610 $aPhotosynthesis 610 $aCancer 610 $aScience 610 $aMedical 615 0$aPhotosensitizing compounds$xTherapeutic use$xTesting 615 0$aPhotosensitizing compounds 615 0$aCancer$xPhotochemotherapy 676 $a615.8/31 700 $aBock$b Gregory$0322650 702 $aHarnett$b Sara 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910829903103321 996 $aPhotosensitizing compounds$94094898 997 $aUNINA