LEADER 03927nam 2200649Ia 450 001 9910829885703321 005 20230828200726.0 010 $a1-280-44892-X 010 $a9786610448920 010 $a0-470-03224-3 010 $a0-470-03223-5 035 $a(CKB)1000000000357296 035 $a(EBL)257695 035 $a(SSID)ssj0000230795 035 $a(PQKBManifestationID)11193952 035 $a(PQKBTitleCode)TC0000230795 035 $a(PQKBWorkID)10179510 035 $a(PQKB)11579249 035 $a(MiAaPQ)EBC257695 035 $a(OCoLC)86221654 035 $a(EXLCZ)991000000000357296 100 $a20060503d2006 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aPurinergic signalling in neuron-glia interactions$b[electronic resource] /$f[editors, Derek J. Chadwick and Jamie Goode.] 210 $aChichester $cJohn Wiley$d2006 215 $a1 online resource (303 p.) 225 1 $aNovartis Foundation symposium ;$v276 300 $a"Symposium on Purinergic signalling in neuron-glia interactions held at the Novartis Foundation, London 7-9 June 2003."--Contents p. 311 $a0-470-01860-7 320 $aIncludes bibliographical references and indexes. 327 $aCover; Contents; Chair's introduction; A brief look at glial cells; The acquisition of myelin: a success story; DISCUSSION; Purinergic signalling-an overview; DISCUSSION; General discussion I; Agonists and antagonists for P2 receptors; DISCUSSION; Regulated release of nucleotides and UDP sugars from astrocytoma cells; DISCUSSION; Pathophysiological roles of P2 receptors in glial cells; DISCUSSION; General discussion II; Ectonucleotidases in the nervous system; DISCUSSION; P2 receptor signalling, proliferation of astrocytes, and expression of molecules involved in cell-cell interactions 327 $aDISCUSSIONNerve impulses regulate myelination through purinergic signalling; DISCUSSION; Cross-talk between growth factor and purinergic signalling regulates Schwann cell proliferation; DISCUSSION; Promoting neurotrophic effects by GPCR ligands; DISCUSSION; A purinergic dialogue between glia and neurons in the retina; DISCUSSION; Bidirectional astrocyte-neuron communication: the many roles of glutamate and ATP; DISCUSSION; Neuron-glia interactions at the neuromuscular synapse; DISCUSSION; General discussion III; Functional neuronal-glial anatomical remodelling in the hypothalamus; DISCUSSION 327 $aPurinergic signalling between axons and microgliaDISCUSSION; ATP receptors of microglia involved in pain; DISCUSSION; Final discussion; Contributor index; Subject index 330 $aATP, the intracellular energy source, is also an extremely important cell-cell signalling molecule for a wide variety of cells across evolutionarily diverse organisms. The extracellular biochemistry of ATP and its derivatives is complex, and the multiple membrane receptors that it activates are linked to many intracellular signalling systems. Purinergic signalling affects a diverse range of cellular phenomena, including ion channel function, cytoskeletal dynamics, gene expression, secretion, cell proliferation, differentiation and cell death. Recently, this class of signalling molecules and 410 0$aNovartis Foundation symposium ;$v276. 606 $aNeurology$vCongresses 606 $aNeuroglia$vCongresses 606 $aPurines$xReceptors$vCongresses 615 0$aNeurology 615 0$aNeuroglia 615 0$aPurines$xReceptors 676 $a573.85 676 $a612.8043 701 $aChadwick$b Derek$091632 701 $aGoode$b Jamie$0283336 712 02$aNovartis Foundation. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910829885703321 996 $aPurinergic signalling in neuron-glia interactions$94106611 997 $aUNINA