LEADER 03576nam 2200601 a 450 001 9910829877703321 005 20230421044627.0 010 $a1-282-45500-1 010 $a9786612455001 010 $a0-470-51535-X 010 $a0-470-51536-8 035 $a(CKB)1000000000377330 035 $a(EBL)470617 035 $a(SSID)ssj0000388269 035 $a(PQKBManifestationID)11287663 035 $a(PQKBTitleCode)TC0000388269 035 $a(PQKBWorkID)10411492 035 $a(PQKB)11789472 035 $a(MiAaPQ)EBC470617 035 $a(OCoLC)181183420 035 $a(EXLCZ)991000000000377330 100 $a19961203d1997 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aAntibiotic resistance$b[electronic resource] $eorigins, evolution, selection, and spread 210 $aChichester ;$aNew York $cWiley$d1997 215 $a1 online resource (262 p.) 225 1 $aCiba Foundation symposium ;$v207 300 $a"Editors: Derek J. Chadwick (organizer) and Jamie Goode"--P. v. 311 $a0-471-97105-7 320 $aIncludes bibliographical references and index. 327 $aANTIBIOTIC RESISTANCE: ORIGINS, EVOLUTION, SELECTION AND SPREAD; Contents; Participants; Antibiotic resistance: an ecological imbalance; Origins, acquisition and dissemination of antibiotic resistance determinants; The relationship between erythromycin consumption and resistance in Finland; The contribution of antibiotic use on the frequency of antibiotic resistance in hospitals; Impact of antibiotic use in animal feeding on resistance of bacterial pathogens in humans; The effect of monitoring of antibiotic use on decreasing antibiotic resistance in the hospital 327 $aThe antibiotic selective process: concentration-specific amplification of low-level resistant populationsThe within-host population dynamics of antibacterial chemotherapy: conditions for the evolution of resistance; The cost of antibiotic resistance-from the perspective of a bacterium; The evolution of b-lactamases; Molecular evolution of multiply= antibiotic-resistant staphylococci; Mobile gene cassettes and integrons: moving antibiotic resistance genes in Gram-negative bacteria; Genetic mobility and distribution of tetracycline resistance determinants 327 $aEpidemiological factors influencing the emergence of antimicrobial resistanceSummarv; Index of contributors; Subject index 330 $aAntibiotic Resistance: Origins, Evolution, Selection and Spread Chairman: Stuart B. Levy 1997 Over the last 50 years, the rapid increase in the use of antibiotics, not only in people, but also in animal husbandry and agriculture, has delivered a selection unprecedented in the history of evolution. Consequently, society is facing one of its gravest public health problems-the emergence of infectious bacteria with resistance to many, and in some cases all, available antibiotics. This book brings together a multidisciplinary group of experts to discuss this problem. It begins by examining the orig 410 0$aCiba Foundation symposium ;$v207. 606 $aDrug resistance in microorganisms$vCongresses 615 0$aDrug resistance in microorganisms 676 $a616.01 676 $a616.014 676 $a616/.01 701 $aChadwick$b Derek$091632 701 $aGoode$b Jamie$0283336 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910829877703321 996 $aAntibiotic resistance$94106556 997 $aUNINA