LEADER 03345nam 2200649 a 450 001 9910829866403321 005 20230421044507.0 010 $a1-282-12245-2 010 $a9786612122453 010 $a0-470-51471-X 010 $a0-470-51472-8 035 $a(CKB)1000000000376019 035 $a(EBL)470580 035 $a(SSID)ssj0000357652 035 $a(PQKBManifestationID)11263413 035 $a(PQKBTitleCode)TC0000357652 035 $a(PQKBWorkID)10354083 035 $a(PQKB)11299418 035 $a(MiAaPQ)EBC470580 035 $a(OCoLC)181178218 035 $a(EXLCZ)991000000000376019 100 $a19940927d1995 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aCell adhesion and human disease$b[electronic resource] /$f[editors, Joan Marsh and Jamie A. Goode] 210 $aChichester ;$aNew York $cWiley$d1995 215 $a1 online resource (256 p.) 225 1 $aCiba Foundation symposium ;$v189 300 $a"Ciba Foundation"--Cover. 300 $a"Symposium on Cell adhesion and human disease, held at the Ciba Foundation, London 17-19 May 1994"--P. v. 311 $a0-471-95279-6 320 $aIncludes bibliographical references and indexes. 327 $aCELL ADHESION AND HUMAN DISEASE; Contents; Participants; Chairman's introduction; P-selectin knockout: a mouse model for various human diseases; Creation and characterization of E-selectin- and VCAM-1 -deficient mice; Von Willebrand's disease and the mechanisms of platelet function; Leukocyte adhesion deficiency (LAD) II; Leukocyte and endothelial adhesion molecules in ischaemialreperfusion injuries; General discussion I; The integrin (VLA-4) as a therapeutic target; Adhesion molecules in cutaneous inflammation; Defective cell-cell adhesion in the epidermis 327 $aE-cadherin as an invasion suppressorThe role of CD44 splice variants in human metastatic cancer; Early metastasis of human solid tumours: expression of cell adhesion molecules; General discussion I I; Mechanisms fibronectin b i m p I icat ions of VCAM-1 and nding to or integr rational drug design integrin CY& : n function and; General d iscussio n II; Treatment of inflammatory diseases with a monoclonal antibody to intercellular adhesion molecule 1; Identification of endogenous protein-associated carbohydrate ligands for E-selectin; Final discussion; Index of contributors; Subject index 330 $aExperts in their respective fields present papers concerned with the range of human diseases caused by defective or abnormal functioning of cell adhesion molecules. Discusses new therapeutic approaches to these maladies. 410 0$aCiba Foundation symposium ;$v189. 606 $aCell adhesion$vCongresses 606 $aCell adhesion molecules$vCongresses 606 $aPhysiology, Pathological$vCongresses 615 0$aCell adhesion 615 0$aCell adhesion molecules 615 0$aPhysiology, Pathological 676 $a611.01815 676 $a616.07 701 $aMarsh$b Joan$091633 701 $aGoode$b Jamie$0283336 712 02$aCiba Foundation. 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910829866403321 996 $aCell adhesion and human disease$93928230 997 $aUNINA