LEADER 05038nam  2200637Ia 450 
001 9910829040903321
005 20200520144314.0
035   $a(CKB)1000000000450801
035   $a(EBL)3377315
035   $a(SSID)ssj0000249201
035   $a(PQKBManifestationID)11216392
035   $a(PQKBTitleCode)TC0000249201
035   $a(PQKBWorkID)10205604
035   $a(PQKB)10576706
035   $a(OCoLC)58594839
035   $a(MiAaPQ)EBC3377315
035   $a(EXLCZ)991000000000450801
100   $a19941122d1994      uy         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aSpacecraft maximum allowable concentrations for selected airborne contaminants$hVolume 1 /$fSubcommittee on Spacecraft Maximum Allowable Concentrations, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council
205   $a1st ed.
210   $aWashington, D.C. $cNational Academy Press$d1994
215   $a1 online resource (235 p.)
300   $a"The project was supported by the National Aeronautics and Space Administration grant no. NAGW-2239."
311   $a0-309-57222-3 
320   $aIncludes bibliographical references.
327   $a""Spacecraft Maximum Allowable Concentrations for Selected Airborne Contaminants""; ""Copyright""; ""Preface""; ""Contents""; ""Spacecraft Maximum Allowable Concentrations for Selected Airborne Contaminants""; ""INTRODUCTION""; ""SUMMARY OF REPORT ON GUIDELINES FOR DEVELOPING SMACS""; ""REVIEW OF SMAC REPORTS""; ""REFERENCES""; ""Appendix A Executive Summary of Guidelines for Developing Spacecraft Maximum Allowable Concentration for Space Stationa???""; ""EXECUTIVE SUMMARY: SPACECRAFT MAXIMUM ALLOWABLE CONCENTRATIONS FOR SPACE STATION CONTAMINANTS""
327   $a""ENVIRONMENTAL CONTROL AND LIFE-SUPPORT SYSTEM""""MODIFICATION OF CONTAMINANT TOXICITY BY ENVIRONMENTAL FACTORS""; ""SOURCES AND TYPES OF DATA FOR ESTABLISHMENT OF SMACS""; ""Chemical-Physical Characteristics of Toxicants""; ""In Vitro Toxicity Studies""; ""Animal Toxicity Studies""; ""Clinical and Epidemiological Observations""; ""Pharmacokinetics and Metabolism""; ""Biological Markers""; ""RISK ASSESSMENT (DEVELOPMENT OF EXPOSURE CRITERIA)""; ""ISSUES IN MAKING RECOMMENDATIONS FOR THE ESTABLISHMENT OF SMACS""
327   $a""Appendix B Reports on Spacecraft Maximum Allowable Concentrations (SMACs) for Selected Airborne Contaminants""""B1 ACETALDEHYDE""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""OCCURRENCE AND USE""; ""PHARMACOKINETICS AND METABOLISM""; ""TOXICITY SUMMARY""; ""Acute Toxicity""; ""Mucosal Irritation""; ""Miscellaneous Mucosal Effects""; ""Lethality""; ""Subchronic and Chronic Toxicity""; ""Nasal Toxicity""; ""Pulmonary and Renal Toxicity""; ""Carcinogenicity""; ""Genotoxicity""; ""Reproductive and Developmental Toxicity""; ""Synergistic Effects""; ""RATIONALE""; ""Carcinogenicity""
327   $a""Mucosal Irritation""""The Establishment of SMACs""; ""REFERENCES""; ""B2 AMMONIA""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""OCCURRENCE AND USE""; ""PHARMACOKINETICS AND METABOLISM""; ""TOXICITY SUMMARY""; ""Mechanisms of Tissue Injuries""; ""Mucosal Irritation in Naive Subjects""; ""Mucosal Irritation in Adapted Subjects""; ""Mucosal Irritation in Subjects Of Unknown Adaptation Status""; ""Toxic Effects of Massive Exposures""; ""Animal Models of Ammonia's Respiratory Damage""; ""Metabolic Acidosis""; ""RATIONALE""; ""1-h SMAC and 24-h SMAC""; ""7-d SMAC""; ""30-d SMAC and 180-d SMAC""
327   $a""REFERENCES""""B3 CARBON MONOXIDE""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""OCCURRENCE AND USE""; ""PHARMACOKINETICS""; ""TOXICITY SUMMARY""; ""Acute Toxicity""; ""Adaptation""; ""Subchronic and Chronic Toxicity""; ""Synergistic Effects""; ""RATIONALE""; ""1-h SMAC""; ""24-h SMAC""; ""7-d SMAC""; ""30-d SMAC and 180-d SMAC""; ""1-h and 24-h SMACs Immediately Following CO Exposure""; ""REFERENCES""; ""B4 FORMALDEHYDE""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""OCCURRENCE AND USE""; ""PHARMACOKINETICS AND METABOLISM""; ""TOXICITY SUMMARY""; ""Acute Toxicity""
327   $a""Subchronic and Chronic Toxicity""
606   $aSpace cabin atmospheres
606   $aSpace vehicles$xAir pollution
606   $aSpace vehicles$xAir quality$xStandards
606   $aSpace vehicles$xContamination
606   $aSpace vehicles$xEnvironmental aspects
606   $aToxicology$xResearch$zUnited States
615  0$aSpace cabin atmospheres.
615  0$aSpace vehicles$xAir pollution.
615  0$aSpace vehicles$xAir quality$xStandards.
615  0$aSpace vehicles$xContamination.
615  0$aSpace vehicles$xEnvironmental aspects.
615  0$aToxicology$xResearch
676   $a629.477
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910829040903321
996   $aSpacecraft maximum allowable concentrations for selected airborne contaminants$93935404
997   $aUNINA