LEADER 03413nam 2200493 450 001 9910828363003321 005 20200520144314.0 010 $a1-58528-592-7 035 $a(CKB)5120000000108534 035 $a(MiAaPQ)EBC5557539 035 $a(Au-PeEL)EBL5557539 035 $a(OCoLC)1059419432 035 $a(NjHacI)995120000000108534 035 $a(EXLCZ)995120000000108534 100 $a20181117d2018 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aConcepts in clinical pharmacokietics /$fRobin Southwood, Virginia H. Fleming, Gary Huckaby 205 $aSeventh edition. 210 1$aBethesda, MD :$cASHP publication,$d[2018] 210 4$d2018 215 $a1 online resource (x, 284 pages) 311 $a1-58528-591-9 327 $aIntroduction to pharmacokinetics and pharmacodynamics -- Basic pharmacokinetics -- Half-life, elimination rate, and AUC -- Intravenous bolus administration, multiple drug administration, and steady-state average concentrations -- Relationships of pharmacokinetic parameters and intravenous intermittent and continuous infusions -- Two-compartment models -- Biopharmaceutics : absorption -- Drug distribution and protein binding -- Drug elimination processes -- Nonlinear processes -- Pharmacokinetic variation and model-independent relationships -- Aminoglycosides -- Vancomycin -- Theophylline -- Phenytoin and digoxin. 330 $aUnderstanding the science of pharmacokinetics is a challenge for many pharmacy students and practitioners. Concepts in Clinical Pharmacokinetics, now in its 7th edition, has helped thousands by simplifying this essential, but complex, subject to reflect current practice. The 7th edition has been revised by Robin Southwood, PharmD, BC-ADM, CDE; Virginia H. Fleming, PharmD, BCPS; and Gary Huckaby, PharmD; all experts in clinical pharmacy education. Together, they have updated and expanded the text to include the latest information and insights on concepts through extensive use of correlates, figures, and review questions. Inside you will find: * 15 easy-to-follow lessons, perfect for a semester * Practice quizzes to help chart progress * Enhanced discussion of hemodialysis * A phenytoin "cheat sheet" to help you through the calculations maze * New vancomycin cases based on higher desired vancomycin levels and trough-only dose estimations * Expanded information on modified diet in renal disease formula versus Cockcroft-Gault formula methods * Factors to consider when choosing a dosing/body weight for various equations * Updated clinical correlates, discussion points, references, and questions/answers Concepts in Clinical Pharmacokinetics is the fundamental reference for learning the basic, foundational pharmacokinetics concepts and how to apply them in clinical practice. 606 $aDrugs$xDosage 606 $aPharmacokinetics 615 0$aDrugs$xDosage. 615 0$aPharmacokinetics. 676 $a615.7 700 $aSouthwood$b Robin L.$01605147 702 $aFleming$b Virginia H. 702 $aHuckaby$b Gary 712 02$aAmerican Society of Health-System Pharmacists, 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910828363003321 996 $aConcepts in clinical pharmacokietics$93930241 997 $aUNINA