LEADER 03733nam 2200721 a 450 001 9910827879303321 005 20240516065057.0 010 $a9786613694447 010 $a9781280784057 010 $a1280784059 010 $a9780470720752 010 $a0470720751 010 $a9780470718445 010 $a0470718447 035 $a(CKB)1000000000688147 035 $a(EBL)703914 035 $a(OCoLC)797918497 035 $a(SSID)ssj0000715492 035 $a(PQKBManifestationID)11404031 035 $a(PQKBTitleCode)TC0000715492 035 $a(PQKBWorkID)10705474 035 $a(PQKB)11482713 035 $a(MiAaPQ)EBC703914 035 $a(Au-PeEL)EBL703914 035 $a(CaPaEBR)ebr10575499 035 $a(CaONFJC)MIL369444 035 $a(Perlego)2764229 035 $a(EXLCZ)991000000000688147 100 $a19830801d1983 uy 0 101 0 $aeng 135 $aurcn||||||||| 181 $ctxt 182 $cc 183 $acr 200 10$aMobility and function in proteins and nucleic acids 205 $a1st ed. 210 $aLondon $cPitman$d1983 215 $a1 online resource (369 p.) 225 1 $aCiba Foundation symposium ;$v93 300 $aDescription based upon print version of record. 311 08$a9780470664124 311 08$a0470664126 311 08$a9780272796573 311 08$a0272796573 320 $aIncludes bibliographical references and indexes. 327 $aMobility and J function in proteins and nucleic acids; Contents; Introduction; The role of mobility in the substrate binding and catalytic machinery of enzymes; Discussion; Ligand- induced conformational changes in proteins; Discussion; Mobility and active-site coupling in 2-0x0 acid dehydrogenase complexes; Discussion; The mobility of calcium- trigger proteins and its function; Discussion; Mobility and function in elastin and collagen; Discussion; Flexibility in tobacco mosaic virus; Discussion; The molecular basis of muscle contraction; Discussion 327 $aActin-induced changes in the dynamics of myosin subfragment-1 detected by nuclear magnetic resonance Discussion; Rotational dynamics of spin-labelled muscle proteins; Discussion; Cross-bridge movement in muscle and the conformation of the myosin hinge; Discussion; Nuclear magnetic resonance studies on structure and breathing dynamics of transfer RNA; Discussion; Triplet anisotropy decay measurements of DNA internal motion; Discussion; Conformations and flexibilities of histones and high mobility group (HMG) proteins in chromatin structure and function; Discussion 327 $aLocal and collective motions in protein dynamics Discussion; Soliton theory of protein dynamics; Discussion; Nuclear magnetic resonance studies of mobility in proteins; Discussion; Summary and outlook; FINAL GENERAL DISCUSSION; Closing remarks; Index of contributors; Subject index 330 8 $aThe Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world. 410 0$aCiba Foundation symposium ;$v93. 606 $aNucleic acids$vCongresses 606 $aProteins$vCongresses 615 0$aNucleic acids 615 0$aProteins 676 $a574.87/328 676 $a574.87328 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910827879303321 996 $aMobility and function in proteins and nucleic acids$91938555 997 $aUNINA